Data Definition
NDAR supports phenotypic, imaging, and genetic human subjects data.
Clinical Assessments
NDAR supports clinical data submissions in XML or Microsoft Excel tabular comma separated value (CSV) formats.
The NDAR Clinical Assessments and Imaging Data Dictionary [Last updated: May 19, 2009]
contains the field names, description, field type and range values for the following assessments:
- Autism Diagnostic Observation Schedule – Modules 1 – 4 (2001) -- (1)
- Autism Diagnostic Interview – Revised (2003) -- (1)
- CHARGE Family Characteristics Questionnaire -- (1)
- CHARGE Physical Exam -- (1)
- Karyotype -- (1)
- Modified CHARGE Family Medical History -- (1)
- CHARGE Medical History -- (2)
- NIMH Medical History Questionnaire -- (2)
- Vineland II - Survey (2005) -- (3)
- Vineland II - Parent and Caregiver Rating (2005) -- (3)
- Aberrant Behavior Checklist - Community
- PDD Behavior Inventory – Parent Rating
- Social Communication Questionnaire – Lifetime
- Social Communication Questionnaire – Current
- Social Responsiveness Scale - Current (2005)
- Modified Checklist for Autism in Toddlers (1999)
- MULLEN Scales of Early Learning - AGS Edition (1995)
- Peabody Picture Vocabulary Test – Form A (Third and Fourth Edition)
- Peabody Picture Vocabulary Test – Form B (Third and Fourth Edition)
- Differential Ability Scales – Preschool
- Differential Ability Scales – School Age
- Wechsler Intelligence Scale for Children - IV (2005)
- Wechsler Abbreviated Scale of Intelligence (1999)
- Wechsler Adult Intelligence Scale – IV
Note: Autism Centers of Excellence (ACE) Common Measures include the assessments designated with a (1) above,
either the Charge Medical History or the NIMH Medical History Questionnaire (designated by (2) above), either of the the Vineland II assessements
(designed by (3) above), and an IQ assessment.
The above list will continue to grow. In 2009, NDAR will enable the research field to help modify and expand the
NDAR Data Dictionary. Until then, investigators are requested to locally maintain data not yet supported. See Data Dictionary for more information.
Imaging
NDAR has adopted the MIPAV XML format for gathering metadata on images to be submitted to NDAR.
The
MIPAV (Medical Image Processing, Analysis, and Visualization) application enables quantitative analysis and
visualization of medical images for numerous modalities such as PET, MRI, CT, or microscopy. MIPAV contains a module that will process images and generate the MIPAV XML required for imaging data submission to NDAR.
NDAR supports the receipt of raw brain images in DICOM format. NDAR also supports processed images in a variety of formats including DICOM, MINC 1.0 and 2.0, Analyze, NIfTI-1, AFNI and SPM. If you are using a different file format, please contact ndar@mail.nih.gov to let us to add to our list of supported standards.
The NDAR Clinical Assessments and Imaging Data Dictionary [Last updated: Dec 19, 2008] contains the metadata definition for imaging and defines the field names, description, field type and range values for image metadata to which the MIPAV XML data file(s) must adhere. A sample imaging MIPAV XML file is available for reference.
Genomics
For Genomics data, NDAR has adopted the use of a set of templates for accepting various types of genomics data.
The NDAR Genomics Data Dictionary [Last updated: June 12, 2009] defines the field names and acceptable values for the fields in the template files.
The following ngTemplates have been adopted to define a genomics data submission.
