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Hamilton Rating Scale for Depression



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Element NameData TypeSizeRequiredDescriptionValue RangeNotesAliases
subjectkeyGUIDRequiredThe NDAR Global Unique Identifier (GUID) for research subjectNDAR*nimhid
src_subject_idString20RequiredSubject ID how it's defined in lab/projectid, ptid, subject_id, subjectid, subjid
interview_dateDateRequiredDate on which the interview/genetic test/sampling/imaging was completed. MM/DD/YYYYRequired fieldhamddt, testdate, v1_hamd_date, v2_hamd_date, visit_date
interview_ageIntegerRequiredAge in months at the time of the interview/test/sampling/imaging.0 :: 1260Age is rounded to chronological month. If the research participant is 15-days-old at time of interview, the appropriate value would be 0 months. If the participant is 16-days-old, the value would be 1 month.age, v1_hamd_age, v2_hamd_age
genderString20RequiredSex of the subjectM;FM = Male; F = Female
crcidString40RecommendedCRC ID/ROA ID
dateDateRecommendedOpen Label Baseline dateComplete only if starting Open Label Phase. OL Baseline contact is visit where participant is given active drug - included in random data set.
updateIntegerRecommendedUpdated form0;11=Updated
lang_visitIntegerRecommendedLanguage during visit0;11=Spanish; 0=Englishspanish
hsoinIntegerRecommendedHRS Initial insomnia0::20=Absent: No difficulty falling asleep; 1=Mild:Complains of occasional difficulty falling asleep — i.e., more than 1/2 hour; 2=Severe: Complains of nightly difficulty falling asleepham4, hamd4, hamd_06, hamilton4, hrsd4, insom_er, insom_hrsd, insomnia, insomniaearly, v1_hamd_6_insomnia_early, v2_hamd_6_insomnia_early
hmninIntegerRecommendedHRS Middle insomnia0::20=Absent: No difficulty; 1=Mild: Patient complains of being restless and disturbed during the night; 2=Severe: Waking during the night—any getting out of bed rates 2 (except for purposes of voiding)ham5, hamd5, hamd_07, hamilton5, hrsd5, insom_md, insomniamiddle, middle, midinsom_hrsd, v1_hamd_7_insomnia_middle, v2_hamd_7_insomnia_middle
heminIntegerRecommendedHRS Late insomnia0::20=Absent: No difficulty; 1=Mild: Waking in early hours of the morning but goes back to sleep; 2=Severe: Unable to fall asleep again if he gets out of beddelayed, delayinsom_hrsd, ham6, hamd6, hamd_08, hamilton6, hrsd6, insom_lt, insomnialate, v1_hamd_8_insomnia_late, v2_hamd_8_insomnia_late
hmdsdIntegerRecommendedHRS Depressed mood0::40=Absent; 1= Doubtful or trivial:These feeling states indicated only on questioning; 2=Mild:These feeling states spontaneously reported verbally; 3=Moderate:Communicates feeling states non-verbally—i.e., through facial expression, posture, voice, and tendency to weep; 4=Severe: Patient reports VIRTUALLY ONLY these feeling states in his spontaneous verbal and non-verbal communicationdepmood, depress, depress_hrsd, depressed, ham1, hamd1, hamd6_1, hamd_01, hamilton1, hrsd1, v1_hamd_1_depressedmood, v2_hamd_1_depressedmood
hpanxIntegerRecommendedHRS Psychic anxiety0::40=Absent: No difficulty; 1=Doubtful or trivial: Subjective tension and irritability; 2=Mild: Worrying about minor matters; 3=Moderate: Apprehensive attitude apparent in face or speech; 4=Severe: Fears expressed without questioninganxietypsychic, ham10, hamd10, hamd6_5, hamd_24, hamilton10, hrsd10, psychic, psychicanx_hrsd, v1_hamd_12_anxiety_psychic, v2_hamd_12_anxiety_psychic
hinsgIntegerRecommendedHRS Loss of insight0::20=Acknowledges being depressed and ill; 1=Acknowledges illness but attributes cause to bad food, climate, over work, virus, need for rest, etc.; 2=Denies being ill at allham17, hamd16, hamd_28, hamilton17, hrsd17, insight, lossinsight_hrsd, v1_hamd_15_insight, v2_hamd_15_insight
happtIntegerRecommendedHRS Appetite0::20=Normal appetite; 1=Mild reduction; 2=Moderate to severe reductionappetite_hrsd, ham12, v1_hamd_4_somaticgastro, v2_hamd_4_somaticgastro
hwlIntegerRecommendedHRS Weight loss0::20=No weight loss; 1=Probably weight loss associated with present illness; 2=Definite (according to patient) weight lossham16, hamd_14, hamilton16b, hrsd16a, weight, wghtloss, wghtlss_hrsd, wtloss
hsanxIntegerRecommendedHRS Somatic anxiety0::40 = Absent: No somatic anxiety; 1 =Doubtful or trivial: Minor symptoms elicited only by direct questioning; 2= Mild: Spontaneously describes symptoms, which are not marked or incapacitating; 3=Moderate: Greater number and frequency of symptoms; accompanied by subjective distress and serve to impair normal functioning; 4 = Severe: Symptoms are numerous, persistent and incapacitating much of the timeanxietysomatic, ham11, hamd11, hamd_26, hamilton11, hrsd11, somatic, somaticanx_hrsd, v1_hamd_13_anxiety_somatic, v2_hamd_13_anxiety_somatic
hhypcIntegerRecommendedHRS Hypochondriasis0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeham15, hamd15, hamd_27, hamilton15, hrsd15, hypochon_hrsd, hypochondriasis, hypocodr, v1_hamd_14_hypochond, v2_hamd_14_hypochond
hvwsfIntegerRecommendedHRS Guilt feelings and delusions0::40=Absent; 1=Doubtful or trivial: Self reproach, feels he has let people down; 2=Mild:Ideas of guilt or rumination over past errors or sinful deeds; 3=Moderate: Present illness is a punishment. Delusions of guilt; 4=Severe: Hears accusatory or denunciatory voices and/or experiences threatening visual hallucinationsguilt, guilt_hrsd, ham2, hamd2, hamd6_2, hamd_21, hamilton2, hrsd2, v1_hamd_10_guilt, v2_hamd_10_guilt
hsuicIntegerRecommendedHRS Suicide0::40=Absent; 1=Feels life is empty; 2=Wishes for death; 3=Active suicidal thoughts; 4=Serious suicide attemptham3, hamd3, hamd_23, hamilton3, hrsd3, suicide, suicide_hrsd, v1_hamd_11_suicide, v2_hamd_11_suicide
hintrIntegerRecommendedHRS Work and interests0::40=Absent: No difficulty; 1=Doubtful or trivial: Thoughts and feelings of incapacity , fatigue or weakness related to activities; work or hobbies; 2=Mild: Loss of interest in activity; hobbies or work—either directly reported by patient, or indirect in listlessness, indecision and vacillation (feels he has to push self to work or activities); 3=Moderate: Decrease in actual time spent in activities or decrease in productivity; 4=Severe: Stopped working because of present illnessactivities, apathy_hrsd, ham7, hamd6_3, hamd7, hamd_03, hamilton7, hrsd7, v1_hamd_2_workandactivities, v2_hamd_2_workandactivities, work1, workact
hengyIntegerRecommendedHRS Somatic energy0::20 = Absent: No change in energy; 1 = Mild: Infrequent, feelings noted but not marked; 2 =Obvious and severe: Tires very quickly, exhausted much of the time, spontaneously mentions symptomsham13, somaenergy_hrsd
hslowIntegerRecommendedHRS Retardation. Psychomotor (Slowness of thought and speech; impair ed ability to concentrate; decr eased motor activity).0::40=Absent: Normal speech and thought; 1=Mild: Slight retardation at interview; 2=Moderate: Obvious retardation at interview; 3=Severe: Interview difficult; 4=Extreme: Complete stuporham8, hamd6_4, hamd8, hamd_30, hamilton8, hrsd8, psychoretard_hrsd, retard, retardation, v1_hamd_16_retardation, v2_hamd_16_retardation
hagitIntegerRecommendedHRS Agitation0::40=Absent: None; 1=Mild: Fidgetiness; 2=Moderate: Playing with hands, hair, etc.;3=Severe: Moving about, can't sit still; 4=Extreme: Hand wringing, nail biting, hair-pulling, biting of lipsagitate, agitation, agitation_hrsd, ham9, hamd9, hamd_29, hamilton9, hrsd9, v1_hamd_17_agitation, v2_hamd_17_agitation
hsexIntegerRecommendedHRS Libido0::20 =Absent: No loss or inadequate information; 1 = Mild: Loss of libido and/or some impairment of sexual function; 2 =Severe: Complete loss of sexual drivegenital, ham14, hamd14, hamd_20, libido_hrsd, v1_hamd_3_genitalsymptoms, v2_hamd_3_genitalsymptoms
hdtot_rIntegerRecommendedHRS total score (recorded)hrsdscr, score_hrsd, v1_hamd_totalscore, v2_hamd_totalscore
days_baselineIntegerRecommendedDays since baselinedate, vdahrsd
levelString10RecommendedTreatment level
monthIntegerRecommendedMonth in Follow-Up
time_pointIntegerRecommendedAssessment time point5= Screening; 10= Baseline; 21, 22, 23 = Mid-point 1, 2, 3; 30= End-of-treatment; 41, 42, 43= Follow-up1, 2, 3 etc.
hrsd_totalIntegerRecommendedHRS total scorehrsd_r
hamd_02IntegerRecommendedHopelessness0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeham23, hopeless, hopelessness
hamd_04IntegerRecommendedHelplessness0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeham22, helpless, helplessness
hamd_05IntegerRecommendedSocial withdrawal0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severehamilton23
hamd_09IntegerRecommendedHypersomnia0::20 =Absent; 1 =Mild: Less than 60 minutes; 2 = Obvious and definite: goes to bed more than 60 minutes earlier on most nightshamilton28, hypersomnia
hamd_10IntegerRecommendedSomatic symptoms gastrointestinal0::20=Normal; 1=Mild; 2=Moderate to severegastro, hamd12, hamilton12, hrsd12, symptomsgastro
hamd_11IntegerRecommendedAppetite increase0::30=Absent; 1=Mild: Minimal or slight increase in appetite, food cravings; 2=Obvious: Definite and marked increase in food Intake; 3=Severeappetite, apptinc, hamilton24
hamd_12IntegerRecommendedIncreased eating0::30=Absent; 1=Mild; 2=Moderate; 3=Markedhamilton25
hamd_13IntegerRecommendedCarbohydrate craving0::30=Absent; 1=Mild; 2=Moderate; 3=Markedcarbcrav, hamilton26
hamd_15IntegerRecommended14b Loss of weight rated by ward staff0::20=Normal; 1=Mild; 2=Moderate to severehamd17
hamd_16IntegerRecommended15a Weight Gain0::20 = Absent; 1 = Doubtful or minimal: Less than 5 lbs in 2 wks; 2 = Obvious: Greater than or equal to 5 lbs over the past 2 weekshamilton27, wtgain
hamd_17IntegerRecommended15b Gain of weight rated by ward staff0::20=Normal; 1=Mild; 2=Moderate to severe
hamd_18IntegerRecommendedSomatic symptoms general0::20=Normal; 1=Mild; 2=Moderate to severegeneral, hamd13, hamd6_6, hamilton13, hrsd13, som_gen, symptomsgeneral, v1_hamd_9_somaticgeneral, v2_hamd_9_somaticgeneral
hamd_19IntegerRecommendedFatiguability0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeanergia, fatigue, hamilton22
hamd_22IntegerRecommendedWorthlessness0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeham24, worthles, worthlessness
hamd_25IntegerRecommendedConcentration0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severe
hamd_31IntegerRecommended29A. (H18) Diurnal Variation0::30=No variation or not currently depressed; 1=Worse in AM; 2=Worse in PM; 3=Worse in afternoondepint, ham18a
hamd_32IntegerRecommended29B. When present, mark the severity of the variation:0::20=Normal; 1=Mild; 2=Moderate to severeham18
hamd_33IntegerRecommendedDepersonalization/derealization0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severedeperson, depersonalization, dereal, ham19, hamilton19
hamd_34IntegerRecommendedParanoid symptoms0::40=Absent; 1=Mild; 2=Moderate; 3=Moderately severe; 4=Severeham20, hamilton20, paranoia, paranoid
hamd_35IntegerRecommendedObsessive and compulsive symptoms0::20=Normal; 1=Mild; 2=Moderate to severeham21, hamilton21, hocd, obsess, obsession
hamd_36FloatRecommendedHAMD Total 17 Item Scoreham17tot, hamdscor, score17
hamd_score_24FloatRecommendedHAMD Total 24 Item Scoreham24tot, score, score24
subject_descriptionString4,000RecommendedSubject related information (e.g the affection, phenotype, disease information, etc.).
siteString100RecommendedSiteStudy Sitesiteid
session_idString20Recommendedsession ID/screening IDscreeningid
visitString50RecommendedVisit nameCharacter description of each type of visitvisit_name, visitn, visitnum
version_formString100RecommendedForm usedform_name
completedIntegerRecommendedChecks if completed0::20=No; 1=Yes; 2=Yes, losttstst
weekFloatRecommendedWeek in level/study99=week 10-week 14intid
hypersom_1IntegerRecommendedHypersomnia: During the past week, have you been sleeping too much?0::40=No increase in sleep length, 1=At least one hour increase, 2=2+hours increase, 3=3+hours increase, 4=4+hours increase,
hyplenIntegerRecommendedSleep length used to measure Hypersomnia1;21=Euthymic, 2=8-Hour,
ca220IntegerRecommendedCurrent condition - Other depressive symptoms: Diurnal variation1::31=Worse in morning; 2=Worse in evening; 3=No differencedepintim
diurvarIntegerRecommendedDiurnal variation: mood/energy0::30=No variation or not currently present; 1=Mild intensity; 2=Moderate intensity;3=Severe intensitydiurnal, diurnalv
diurtmIntegerRecommendedDiurnal variation mood/energy: time period1;21=Afternoon;2=Eveningdiurnalampm
phaseIntegerRecommendedPhase9 =follow up
vis_typeIntegerRecommendedVisit type0::21=Phone; 0=doctor's office; 2=No, not phone interviewphone
hwl_hxIntegerRecommendedHRS Weight loss by history0::30=No weight loss; 1=Probable weight loss associated with present illness; 2=Definite weight loss; 3= not assessedhamilton16a, v1_hamd_5_weightloss_history, v2_hamd_5_weightloss_history
hwl_wkIntegerRecommendedHRS Weight loss by week0::30=Less than 1lb. during past week; 1=Greater than 1lb. During the past week; 2=Greater than 2lb. during the past week; 3=not assessedhrsd16b, v1_hamd_5_weightloss_weekly, v2_hamd_5_weightloss_weekly
date_updatedDateRecommendedDate record updatededit_date
neurotmhString10RecommendedTime Hourstimeh
neurotmmString10RecommendedTime Minutestimem
study_idIntegerRecommendedStudy ID number46=Acute Phase; 47=Stabilization Phase
mildtimeString2RecommendedDiurnal variation: mild variation timeAM;PMeosdthdt
sevtimeString2RecommendedDiurnal variation: severe variation timeAM;PMeosalvdt
saps_ad10IntegerRecommendedRater number
ksd1durIntegerRecommendedDuration of Depressed Mood (weeks)888=NA; 999=Missingv1_hamd_1_depressedmood_length, v2_hamd_1_depressedmood_length
visnumFloatRecommendedNumeric Visit Number-1.5 = Pre-Screening; -1 = Screening; 0 = Baseline; ## = Visit ## (from 1 to 10); Whole numbers = standard monthly visits; #.001 - #.009 = Unscheduled; #.1 = End of Phase 1; #.2 = End of Phase 2; #.3 = End of Phase 3; #.4 = End of Open Choice Phase; #.5 = End of Study; #.6 = Genetic Analysis; 1000=all visits
hamsc21IntegerRecommendedScore 21 itemssum items 1-21 (including 16A, 16B, and 18B--but not 18A following Rating Instructions)
hamsc28IntegerRecommendedscore 28 itemssum items 1-28 (including 16A, 16B, and 18B--but not 18A following Rating Instructions)
ham18aIntegerRecommendedDiurnal Variation Severity AM0::2GRID D = Symptom Intensity Absent; Mild or Probable; Marked or Definite.
ham18bIntegerRecommendedDiurnal Variation Severity PM0::2GRID D = Symptom Intensity Absent; Mild or Probable; Marked or Definite.
me2IntegerRecommendedStatus0;10 = Past [Inactive]; 1 = Active
hsleepIntegerRecommendedOversleeping0::20 = Absent; 1 = Mild or infrequently: Oversleeps less than 60 minutes; 2 =Obvious or definite: Oversleeps more than 60 minutes most days
hnapIntegerRecommendedNapping0::20 = Absent; 1 = Mild or infrequently: Naps less than 30 minutes; 2 =Obvious or definite: Naps more than 30 minutes most days
hpreIntegerRecommendedPsychic Retardation (Slowness of speech and thought processes. Describes inhibition of will or feeling as if thought processes are paralyzed)0::40 = Absent; 1 = Mild: Slight slowing of speech or thought; 2 = Moderate: Delayed in answering questions, describes volitional inhibition; 3 = Severe: Slowness of speech and thought processes sufficient to markedly prolong interview; 4 =Extreme: Nearly mute, minimally responsive
hmreIntegerRecommendedMotoric Retardation (Slowness in movement and affective expression.)0::40= Absent; 1 = Mild: Slight flattening of affect, fixed expression; 2 = Moderate: Monotonous voice and decrease in spontaneous movement; 3 = Severe: Obvious slowness of movement and gait; blunted affect; 4 =Extreme: Stuporous. Marked motoric retardation in gait and posture
scoreatypIntegerRecommendedsum of items 25, 26, 27, and 28 on the assessment
hrsd_24IntegerRecommendedRejection Sensitivity0::30=Absent; 1=Mild; 2=Moderate; 3=Severerejection
hrsd_26IntegerRecommendedHypersomnia (severity level)0::30=Absent; 1=Mild; 2=Moderate; 3=Severe
Data Structure

This page displays the data structure defined for the measure identified in the title and structure short name. The table below displays a list of data elements in this structure (also called variables) and the following information:

  • Element Name: This is the standard element name
  • Data Type: Which type of data this element is, e.g. String, Float, File location.
  • Size: If applicable, the character limit of this element
  • Required: This column displays whether the element is Required for valid submissions, Recommended for valid submissions, Conditional on other elements, or Optional
  • Description: A basic description
  • Value Range: Which values can appear validly in this element (case sensitive for strings)
  • Notes: Expanded description or notes on coding of values
  • Aliases: A list of currently supported Aliases (alternate element names)
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Distribution for DataStructure: hrsd01 and Element:
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