|
subjectkey |
GUID |
|
Required |
The NDAR Global Unique Identifier (GUID) for research subject |
NDAR*
|
|
|
|
src_subject_id |
String |
20
|
Required |
Subject ID how it's defined in lab/project |
|
|
catieid |
|
interview_date |
Date |
|
Required |
Date on which the interview/genetic test/sampling/imaging/biospecimen was completed. MM/DD/YYYY |
|
|
|
|
interview_age |
Integer |
|
Required |
Age in months at the time of the interview/test/sampling/imaging. |
0::1440
|
Age is rounded to chronological month. If the research participant is 15-days-old at time of interview, the appropriate value would be 0 months. If the participant is 16-days-old, the value would be 1 month.
|
|
|
sex |
String |
20
|
Required |
Sex of subject at birth |
M;F; O; NR
|
M = Male; F = Female; O=Other; NR = Not reported
|
gender |
Query
|
adas01a |
Integer |
|
Recommended |
World Recall Trial 1 |
0::10
|
number of errors
|
|
Query
|
adas01b |
Integer |
|
Recommended |
World Recall Trial 2 |
0::10
|
number of errors
|
|
Query
|
adas01c |
Integer |
|
Recommended |
World Recall Trial 3 |
0::10
|
number of errors
|
|
Query
|
adas02 |
Integer |
|
Recommended |
Naming Objects |
0::5
|
0 = 0-2 items, 1 = 3-5 items, 2 = 6-8 items, 3 = 9-11 items, 4 = 12-14 items, 5 = 15-17 items
|
|
Query
|
adas03 |
Integer |
|
Recommended |
Commands Score |
0::5
|
1 = 1 command incorrect / 4 commands correct
2 = 2 commands incorrect / 3 commands correct
3 = 3 commands incorrect / 2 commands correct
4 = 4 commands incorrect / 1 command correct
5 = all 5 commands incorrect
|
|
Query
|
adas04 |
Integer |
|
Recommended |
Constructional Praxis Score |
0::5
|
0 = all 4 drawn correctly
1 = 1 form drawn incorrectly
2 = 2 forms drawn incorrectly
3 = 3 forms drawn incorrectly
4 = 4 forms drawn incorrectly
5 = no figures, scribbles; parts of forms; words
|
|
Query
|
adas05 |
Integer |
|
Recommended |
Ideational Praxis Score |
0::5
|
0 = all components performed correctly
1 = failure to perform 1 component
2 = failure to perform 2 components
3 = failure to perform 3 components
4 = failure to perform 4 components
5 = failure to perform 5 components
|
|
Query
|
adas06 |
Integer |
|
Recommended |
Orientation Score |
0::8
|
Number of incorrect responses
|
|
Query
|
adas07a |
Integer |
|
Recommended |
World Recognition Trial 1 |
0::12
|
number of errors
|
|
Query
|
adas07b |
Integer |
|
Recommended |
World Recognition Trial 2 |
0::12
|
number of errors
|
|
Query
|
adas07c |
Integer |
|
Recommended |
World Recognition Trial 3 |
0::12
|
number of errors
|
|
Query
|
adas08 |
Integer |
|
Recommended |
Remembering Test Instructions |
0::5
|
0 = patient never needs reminders of instructions
1 = very mild � forgets once
2 = mild � must be reminded 2 times
3 = moderate � must be reminded 3 or 4 times
4 = moderately severe � must be reminded 5 or 6 times
5 = severe � must be reminded 7 or more times
|
|
Query
|
adas09 |
Integer |
|
Recommended |
Spoken Language Ability |
0::5
|
0 = no instances where it is difficult to understand patient
1 = very mild � one instance of lack of understandability
2 = mild � patient has difficulty less than 25% of the time
3 = moderate � patient has difficulty less than 25-50% of the time
4 = moderately severe � patient has difficulty less than 50% of the time
5 = severe � one or two word utterance; fluent, but empty speech; mute
|
|
Query
|
adas10 |
Integer |
|
Recommended |
Word-Finding Difficulty in Spontaneo |
0::5
|
0 = no evidence of word finding difficulty in spontaneous speech
1 = very mild � 1 or 2 instances, not clinically significant
2 = mild � noticeable circumlocution or synonym substitution
3 = moderate � loss of words without compensation on occasion
4 = moderately severe � frequent loss of words without compensation
5 = severe � nearly total loss of content of words; speech sounds empty; 1-2 word utterances
|
|
Query
|
adas11 |
Integer |
|
Recommended |
Comprehension of Spoken Language |
0::5
|
0 = no evidence of poor comprehension
1 = very mild � 1 or 2 instances of misunderstanding
2 = mild � 3-5 instances of misunderstanding
3 = moderate � requires several repetitions and rephrasing
4 = moderately severe � patient only occasionally responds correctly; i.e., yes/no
5 = severe � patient rarely responds to questions appropriately, not due to poverty of speech
|
|
Query
|
adas12 |
Integer |
|
Recommended |
Concentration/ Distractibility |
0::10
|
0 = none, no evidence of poor concentration or distractibility 1 = very mild, one instance of poor concentration 2 = mild, 2-3 instances of poor concentration/distractibility; signs of restlessness and inattentiveness 3 = moderate, 4-5 instances during interview 4 = moderately severe, poor concentration/distractibility throughout much of interview 5 = severe, extreme difficulty in concentration and extremely distractible, unable to complete tasks; 6 = Is goal-oriented, can maintain interest in tasks; 7 = Slightly distractible, but is goal-oriented and can finish tasks with minimal pressure; 8 = Quite distractible; finishes tasks only with considerable pressure; shows minimal goal-oriented behavior; 9 = Extremely distractible, cannot sustain attention for more than a few seconds, regardless of external pressure; 10 = Never starts or gets involved in anything presented to him and therefore cannot be rated.
|
|
Query
|
adas13 |
Integer |
|
Recommended |
Number Cancellation: |
0::40
|
number of targets hit
|
|
Query
|
adas14 |
Integer |
|
Recommended |
Executive Function(maze) |
0::240
|
in seconds
|
|
Query
|
adas_ts |
Float |
|
Recommended |
ADAS Total Score |
0::5000
|
Created variable with 20% missing data rule applied: First, we created 2 intermediate variables: M_RECALL (mean number of words not recalled in the 3 trials): Average of (10-ADAS01A), (10-ADAS01B), (10- ADAS01C).
M_RECOG (mean number of words not recognized in the 3 trials): Average of ADAS07A, ADAS07B, ADAS07C. Total score is calculated as follows: Sum of M_RECALL, ADAS02, ADAS03, ADAS04, ADAS05, ADAS06, M_RECOG, ADAS08, ADAS09, ADAS10, ADAS11
|
|
Query
|
visitid |
Integer |
|
Recommended |
MetaTrial Visit ID |
|
System variable: unique code for each type of visit -use to merge files
|
|
Query
|
visit |
String |
60
|
Recommended |
Visit name |
|
|
|
Query
|
visnum |
Float |
|
Recommended |
Numeric Visit Number |
|
-1.5 = Pre-Screening; -1 = Screening; 0 = Baseline; ## = Visit ## (from 1 to 10); Whole numbers = standard monthly visits; #.001 - #.009 = Unscheduled; #.1 = End of Phase 1; #.2 = End of Phase 2; #.3 = End of Phase 3; #.4 = End of Open Choice Phase; #.5 = End of Study; #.6 = Genetic Analysis; 1000=all visits
|
|
Query
|
phase_ct |
String |
20
|
Recommended |
Current Phase. Phase patient was in at the time of the assessment Phase 4 refers to the follow-up phase. |
Pre-Rand; Phase 1/1A; Phase 2; Phase 3; Phase 4; Phase 1B; Open-Choice Phase; Screening; Phase 1
|
|
|
Query
|
last1 |
Integer |
|
Recommended |
Flag Last Phase 1/1A Visit |
|
1=Yes for all records meeting this criteria
|
|
Query
|
base1 |
Integer |
|
Recommended |
Flag Baseline Phase 1/1A Visit |
|
1=Yes for all records meeting this criteria
|
|
Query
|
base_ts |
Float |
|
Recommended |
Baseline Total Score |
|
Scare at Phase 1 baselline
|
|
Query
|
c_ts |
Float |
|
Recommended |
Changed from Baseline ADAS Total Score |
|
Change from Phase 1 baseline
|
|