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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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1 Numbers reported are subjects by age
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

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SelectExperiment IdExperiment NameExperiment Type
  • Select One
  • EEG
  • EGG
  • Eye Tracking
  • Omics
  • fMRI
Created On
886RestfMRI02/14/2018
885SARTfMRI02/14/2018
884Plasma metabolic profileOmics02/05/2018
878Social Challenge AssessmentEye Tracking01/26/2018
877PRV-005-EEGEEG01/22/2018
876Mixed Anti and Pro (vgs) saccade mixed blocked eye trackingEye Tracking01/22/2018
875Attention modulation taskEye Tracking01/17/2018
874ruthldopa resting 17 and 18fMRI01/16/2018
873ruthldopa resting 15 and 16fMRI01/16/2018
872ruthldopa resting 13 and 14fMRI01/16/2018
871ruthldopa resting 11 and 12fMRI01/16/2018
870Resting State fMRIfMRI01/12/2018
869cyberballfMRI01/12/2018
868MDD_PilotfMRI01/12/2018
867Velten Mood Induction State-ItemfMRI01/12/2018
866Emotional Hemifield Task (EHT)EEG01/12/2018
865Genome EditingOmics01/12/2018
864parvizi_eeg_118EEG01/12/2018
863parvizi_eeg_117EEG01/12/2018
862parvizi_eeg_116EEG01/12/2018
861parvizi_eeg_115EEG01/12/2018
860parvizi_eeg_114EEG01/12/2018
859parvizi_eeg_113EEG01/12/2018
858PRV-003-EEGEEG01/12/2018
857PRV-004-EEGEEG01/12/2018
856PRV-007-EEGEEG01/12/2018
855Regulating Emotional Responses to Visual Images Across the Affective Instability SpectrumfMRI01/12/2018
854PRV-002-EEGEEG01/12/2018
853R61 Ezogabine Resting State FMRIfMRI01/11/2018
852Paired AssociatesfMRI01/11/2018
851PRV-001-EEGEEG01/11/2018
850Reward ProcessingfMRI01/11/2018
849Resting EEG (1024 samples/s)EEG01/11/2018
845Fast face -1 runfMRI01/10/2018
844MIST_MAST_fMRIfMRI01/10/2018
843RTT AHA-1Omics01/09/2018
84230 words (simultaneous fMRI and EEG acquisition)EEG01/08/2018
841Neural Correlates of Episodic Retrieval fMRI01/08/2018
84030 words (simultaneous fMRI and EEG acquisition)fMRI01/08/2018
838Memory Guided Saccade Encode and Maintenance v3fMRI01/05/2018
837Memory Guided Saccade Encode and Maintenance v2fMRI01/05/2018
836Food ExposurefMRI01/03/2018
835Model ExposurefMRI01/02/2018
834BlankingEye Tracking12/28/2017
833DoubleStepEye Tracking12/26/2017
832Memory Guided Saccade Encode and Maintenance v1 fMRI12/21/2017
831Mixed Anti and Pro (vgs) saccade mixed blocked taskfMRI12/21/2017
830T1 AlternativefMRI12/19/2017
829fMRI Movie Trailer Video 2fMRI12/18/2017
828fMRI Movie Trailer Video 1fMRI12/18/2017
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Shared

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

General

Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

Funding Source

The ability to associate the funding source for the project is provided. For NIH funded grants, linkage to Project Reporter information (e.g. R01MH123456) is supported. Projects funded by others, including the URL of the project, are listed. Non NIH funded projects will become available here to link that data with the appropriate funding agency.

Supporting Documentation

Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Distance to Freeway and Major Road Data
Rob McConnell 
This collection contains birth address based measures on distance to interstate highway, state highway, major road, and local road for study subjects enrolled in the CHARGE study. **** NOTICE **** Please note that the subjects for this project were pregnant mothers. The phenotype of the child are associated with the mother's data for some of the mothers. The children's clinical data are not available. Contact the PI of this project should you need that information. **** END OF NOTICE ****
NDAR
Funding Completed
Shared
$577,195.00
1,049
0
0
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NIH - Extramural None


R21ES019002-01 Investigating Gene-Environment Interaction in Autism: Air Pollution x 09/28/2009 07/31/2011 Not Reported Not Reported UNIVERSITY OF SOUTHERN CALIFORNIA $577,195.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
78MET Genotypes03/18/2013ApprovedOmics
79Tag SNPs for Inflammatory and Oxidative Stress Genes and Ancestry Markers03/18/2013ApprovedOmics

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

CALINE Traffic Related Pollution Estimates Clinical Assessments 1039
Distance to Roadways Clinical Assessments 1049
Genomics Sample Genomics 611
Genomics Subject Genomics 611
Nitrogen Dioxide (NO2) Exposure Clinical Assessments 1049
Ozone Exposures Clinical Assessments 1049
Particulate Matter 10 (PM10) Exposures Clinical Assessments 1049
Particulate Matter 2.5 (PM2.5) Exposures Clinical Assessments 1049
Traffic Related Pollution (TRP) Estimates Clinical Assessments 1039

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
29120534Create StudyJoint effects of prenatal air pollutant exposure and maternal folic acid supplementation on risk of autism spectrum disorder.Autism research : official journal of the International Society for Autism ResearchGoodrich AJ, Volk HE, Tancredi DJ, Mcconnell R, Lurmann FW, Hansen RL, Schmidt RJJanuary 2018Not Determined
28934093Create StudyCombined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder.Environmental health perspectivesSchmidt RJ, Kogan V, Shelton JF, Delwiche L, Hansen RL, Ozonoff S, Ma CC, Mccanlies EC, Bennett DH, Hertz-Picciotto I, Tancredi DJ, Volk HESeptember 2017Not Determined
28921105Create StudyAssociation Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder.Journal of autism and developmental disordersKerin T, Volk H, Li W, Lurmann F, Eckel S, Mcconnell R, Hertz-Picciotto IJanuary 2018Not Determined
24240654Study (340)Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene.Epidemiology (Cambridge, Mass.)Volk HE, Kerin T, Lurmann F, Hertz-Picciotto I, McConnell R, Campbell DBJanuary 2014Relevant
23404082Create StudyTraffic-related air pollution, particulate matter, and autism.JAMA psychiatryVolk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell RJanuary 2013Not Determined
21156395Create StudyResidential proximity to freeways and autism in the CHARGE study.Environmental health perspectivesVolk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell RJune 2011Not Determined
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Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
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Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Distance to Roadways info iconApproved
Enviromental Evaluation info iconApproved
Nitrogen Dioxide (NO2) Exposure info iconApproved
Particulate Matter 2.5 (PM 2.5) Exposures info iconApproved
Ozone Exposures info iconApproved
Particulate Matter 10 (PM10) Exposures info iconApproved
Traffic Related Pollutant Information info iconApproved
genomics/omics info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study Name Description Number of Subjects
Collection / Total
Data Use State
Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene. Background: Independent studies report association of autism spectrum disorder with air pollution exposure and a functional promoter variant (rs1858830) in the MET receptor tyrosine kinase (MET) gene. Toxicologic data find altered brain Met expression in mice after prenatal exposure to a model air pollutant. Our objective was to investigate whether air pollution exposure and MET rs1858830 genotype interact to alter ASD risk. Methods: We studied 252 cases of autism spectrum disorder and 156 typically developing controls the Childhood Autism Risk from Genetics and the Environment Study. Air pollution exposure was assigned for local traffic-related sources and regional sources (particulate matter, nitrogen dioxide and ozone). MET genotype was determined by direct re-sequencing. Results: Subjects with both MET rs1858830 CC genotype and high air pollutant exposures were at increased risk of autism spectrum disorder compared with subjects who had both the CG/GG genotypes and lower pollutant exposures. A statistical test of multiplicative interaction identified a statistically significant effect between NO2 and MET CC genotype (p=0.03) Conclusions: MET rs1858830 CC genotype and air pollutant exposure may interact to increase autism spectrum disorder risk. 209 / 209 Primary Analysis Shared
* Data not on individual level
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