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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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General

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For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Novel computational methods for higher order diffusion MRI in autism
Ragini Verma 
We aim at developing computational methods for processing and analysis of high angular resolution diffusion imaging data that has been fitted with higher order diffusion models (HOMs). Compared to the tensor model in diffusion tensor imaging (DTI), HOMs provide a much richer understanding of pathology-based connectivity changes in complex WM regions, as well as a quantification of the degree of abnormality of WM. These imaging measures when correlated with clinical measures of symptom severity will provide additional insight into the pathology and its progression, thus making this project very clinically significant.
NDAR
Closed
Shared
$3,323,309.00
9
20
239

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NIH - Extramural None


R01MH092862-01 Novel computational methods for higher order diffusion MRI in autism 09/28/2010 07/31/2015 20 239 UNIVERSITY OF PENNSYLVANIA $3,323,309.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Image Imaging 9

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
26833832Create StudyEstablishing a link between sex-related differences in the structural connectome and behaviour.Philosophical transactions of the Royal Society of London. Series B, Biological sciencesTunç B, Solmaz B, Parker D, Satterthwaite TD, Elliott MA, Calkins ME, Ruparel K, Gur RE, Gur RC, Verma RFebruary 19, 2016Not Determined
26754839Create StudyThe white matter query language: a novel approach for describing human white matter anatomy.Brain structure & functionWassermann D, Makris N, Rathi Y, Shenton M, Kikinis R, Kubicki M, Westin CFJanuary 11, 2016Not Relevant
26678299Create StudyIndividualized Map of White Matter Pathways: Connectivity-Based Paradigm for Neurosurgical Planning.NeurosurgeryTunç B, Ingalhalikar M, Parker D, Lecoeur J, Singh N, Wolf RL, Macyszyn L, Brem S, Verma RDecember 16, 2015Not Determined
26674972Create StudyOn characterizing population commonalities and subject variations in brain networks.Medical image analysisGhanbari Y, Bloy L, Tunc B, Shankar V, Roberts TP, Edgar JC, Schultz RT, Verma RDecember 1, 2015Not Determined
26569619Create StudyUnifying Inference of Meso-Scale Structures in Networks.PloS oneTunç B, Verma R2015Not Determined
26428956Create StudySparse deconvolution of higher order tensor for fiber orientation distribution estimation.Artificial intelligence in medicineFeng Y, Wu Y, Rathi Y, Westin CFNovember 2015Not Determined
26082890Create StudyReconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography.NeuroImage. ClinicalChen Z, Tie Y, Olubiyi O, Rigolo L, Mehrtash A, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ2015Not Determined
25604464Create StudyPlasticity of left perisylvian white-matter tracts is associated with individual differences in math learning.Brain structure & functionJolles D, Wassermann D, Chokhani R, Richardson J, Tenison C, Bammer R, Fuchs L, Supekar K, Menon VApril 2016Not Determined
25465846Create StudyOn facilitating the use of HARDI in population studies by creating rotation-invariant markers.Medical image analysisCaruyer E, Verma RFebruary 2015Not Determined
25364303Create StudyA comparative study of 16 tractography algorithms for the corticospinal tract: reproducibility and subject-specificity.Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and ExhibitionCaruyer E, Bloy L, Tunç B, Lecoeur J, Shankar V, Verma R2014Not Determined
25320801Create StudyMeasurement tensors in diffusion MRI: generalizing the concept of diffusion encoding.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionWestin CF, Szczepankiewicz F, Pasternak O, Ozarslan E, Topgaard D, Knutsson H, Nilsson M2014Not Determined
25287217Create StudyDisrupted structural connectome is associated with both psychometric and real-world neuropsychological impairment in diffuse traumatic brain injury.Journal of the International Neuropsychological Society : JINSKim J, Parker D, Whyte J, Hart T, Pluta J, Ingalhalikar M, Coslett HB, Verma ROctober 2014Not Determined
25134977Create StudyAutomated tract extraction via atlas based Adaptive Clustering.NeuroImageTunç B, Parker WA, Ingalhalikar M, Verma RNovember 15, 2014Not Determined
25126717Create StudyThe extent of diffusion MRI markers of neuroinflammation and white matter deterioration in chronic schizophrenia.Schizophrenia researchPasternak O, Westin CF, Dahlben B, Bouix S, Kubicki MJanuary 2015Not Determined
25066750Create StudyFusion of white and gray matter geometry: a framework for investigating brain development.Medical image analysisSavadjiev P, Rathi Y, Bouix S, Smith AR, Schultz RT, Verma R, Westin CFDecember 2014Not Determined
25047866Create StudyMulti-shell diffusion signal recovery from sparse measurements.Medical image analysisRathi Y, Michailovich O, Laun F, Setsompop K, Grant PE, Westin CFOctober 2014Not Determined
25037933Create StudyIdentifying group discriminative and age regressive sub-networks from DTI-based connectivity via a unified framework of non-negative matrix factorization and graph embedding.Medical image analysisGhanbari Y, Smith AR, Schultz RT, Verma RDecember 2014Not Determined
24983132Create StudyCreating multimodal predictors using missing data: classifying and subtyping autism spectrum disorder.Journal of neuroscience methodsIngalhalikar M, Parker WA, Bloy L, Roberts TP, Verma RSeptember 30, 2014Not Determined
24799135Create StudyPUNCH: Population Characterization of Heterogeneity.NeuroImageTunc B, Ghanbari Y, Smith AR, Pandey J, Browne A, Schultz RT, Verma RSeptember 2014Not Determined
24684013Create StudyMultinomial probabilistic fiber representation for connectivity driven clustering.Information processing in medical imaging : proceedings of the ... conferenceTunç B, Smith AR, Wasserman D, Pennec X, Wells WM, Verma R, Pohl KM2013Not Determined
24683979Create StudyLocality preserving non-negative basis learning with graph embedding.Information processing in medical imaging : proceedings of the ... conferenceGhanbari Y, Herrington J, Gur RC, Schultz RT, Verma R2013Not Determined
24505722Create StudyOn describing human white matter anatomy: the white matter query language.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionWassermann D, Makris N, Rathi Y, Shenton M, Kikinis R, Kubicki M, Westin CF2013Not Determined
24505653Create StudyConnectivity subnetwork learning for pathology and developmental variations.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionGhanbari Y, Smith AR, Schultz RT, Verma R2013Not Determined
24505648Create StudyCombining surface and fiber geometry: an integrated approach to brain morphology.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionSavadjiev P, Rathi Y, Bouix S, Smith AR, Schultz RT, Verma R, Westin CF2013Not Determined
24419463Create StudyDIFFEOMORPHIC POINT SET REGISTRATION USING NON-STATIONARY MIXTURE MODELS.Proceedings. IEEE International Symposium on Biomedical ImagingWassermann D, Ross J, Washko G, Westin CF, Estépar RSJanuary 2013Not Relevant
24402118Create StudyReproducibility of connectivity based parcellation: primary visual cortex.Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and ExhibitionLecoeur J, Ingalhalikar M, Verma R2013Not Determined
24297904Create StudySex differences in the structural connectome of the human brain.Proceedings of the National Academy of Sciences of the United States of AmericaIngalhalikar M, Smith A, Parker D, Satterthwaite TD, Elliott MA, Ruparel K, Hakonarson H, Gur RE, Gur RC, Verma RJanuary 14, 2014Not Determined
23963593Create StudyJoint analysis of band-specific functional connectivity and signal complexity in autism.Journal of autism and developmental disordersGhanbari Y, Bloy L, Christopher Edgar J, Blaskey L, Verma R, Roberts TPFebruary 2015Not Determined
23631987Create StudyFiber clustering versus the parcellation-based connectome.NeuroImageO'Donnell LJ, Golby AJ, Westin CFOctober 15, 2013Not Determined
23307635Create StudySexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia.Cerebral cortex (New York, N.Y. : 1991)Savadjiev P, Whitford TJ, Hough ME, Clemm von Hohenberg C, Bouix S, Westin CF, Shenton ME, Crow TJ, James AC, Kubicki MMay 2014Not Determined
23286164Create StudyUsing multiparametric data with missing features for learning patterns of pathology.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionIngalhalikar M, Parker WA, Bloy L, Roberts TP, Verma R2012Not Determined
23286135Create StudyDominant component analysis of electrophysiological connectivity networks.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionGhanbari Y, Bloy L, Batmanghelich K, Roberts TP, Verma R2012Not Determined
23286122Create StudyUnbiased groupwise registration of white matter tractography.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionO'Donnell LJ, Wells WM, Golby AJ, Westin CF2012Not Determined
23286111Create StudyMulti-scale characterization of white matter tract geometry.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionSavadjiev P, Rathi Y, Bouix S, Verma R, Westin CF2012Not Determined
23286062Create StudyEstimation of extracellular volume from regularized multi-shell diffusion MRI.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionPasternak O, Shenton ME, Westin CF2012Not Determined
23286056Create StudyIdentifying sub-populations via unsupervised cluster analysis on multi-edge similarity graphs.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionIngalhalikar M, Smith AR, Bloy L, Gur R, Roberts TP, Verma R2012Not Determined
22551948Create StudyDelayed magnetic mismatch negativity field, but not auditory M100 response, in specific language impairment.NeuroreportRoberts TP, Heiken K, Kahn SY, Qasmieh S, Blaskey L, Solot C, Parker WA, Verma R, Edgar JCMay 30, 2012Not Determined
22500705Create StudyAn integrated framework for high angular resolution diffusion imaging-based investigation of structural connectivity.Brain connectivityBloy L, Ingalhalikar M, Batmanghelich NK, Schultz RT, Roberts TP, Verma R2012Not Determined
22438191Create StudyA review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury.Brain imaging and behaviorShenton ME, Hamoda HM, Schneiderman JS, Bouix S, Pasternak O, Rathi Y, Vu MA, Purohit MP, Helmer K, Koerte I, Lin AP, Westin CF, Kikinis R, Kubicki M, Stern RA, Zafonte RJune 2012Not Determined
22305020Create StudyOptimal real-time estimation in diffusion tensor imaging.Magnetic resonance imagingCasaseca-de-la-Higuera P, Tristán-Vega A, Aja-Fernández S, Alberola-López C, Westin CF, San José Estépar RMay 2012Not Determined
22155376Create StudyfMRI-DTI modeling via landmark distance atlases for prediction and detection of fiber tracts.NeuroImageO'Donnell LJ, Rigolo L, Norton I, Wells WM, Westin CF, Golby AJMarch 2012Not Determined
21995034Create StudyHARDI based pattern classifiers for the identification of white matter pathologies.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionBloy L, Ingalhalikar M, Eavani H, Roberts TP, Schultz RT, Verma R2011Not Determined
21995028Create StudyProbabilistic ODF estimation from reduced HARDI data with sparse regularization.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionTristán-Vega A, Westin CF2011Not Determined
21906832Create StudyEfficient and robust nonlocal means denoising of MR data based on salient features matching.Computer methods and programs in biomedicineTristán-Vega A, García-Pérez V, Aja-Fernández S, Westin CFFebruary 2012Not Determined
21893205Create StudyWhite matter atlas generation using HARDI based automated parcellation.NeuroImageBloy L, Ingalhalikar M, Eavani H, Schultz RT, Roberts TP, Verma RFebruary 15, 2012Not Determined
21837285Create StudyNEURONAL WHITE MATTER PARCELLATION USING SPATIALLY COHERENT NORMALIZED CUTS.Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical ImagingBloy L, Ingalhalikar M, Verma R2011Not Determined
21761667Create StudyWhite matter bundle registration and population analysis based on Gaussian processes.Information processing in medical imaging : proceedings of the ... conferenceWassermann D, Rathi Y, Bouix S, Kubicki M, Kikinis R, Shenton M, Westin CF2011Not Determined
21609768Create StudyDiffusion based abnormality markers of pathology: toward learned diagnostic prediction of ASD.NeuroImageIngalhalikar M, Parker D, Bloy L, Roberts TP, Verma RAugust 1, 2011Not Determined

This tab provides a general status on the data expected to be shared. There are two types of data expected.

  1. By Relevant publications — Those publications that reported for the collection's grant and have a status of "relevant" for sharing are listed first. The grantee is expected to share the data specific to those publications using the NDA Study feature. If a publication is erroneously marked relevant, the PI should simply change the status. When sharing a study, only the outcome measures for the subjects/time-points are shared. Other data that have not met the share date, defined below, will remain embargoed. To initiate study creation, simply login, mark your publication as relevant and click on the link listed to begin.

  2. By Data Structure — The number of subjects expected, received and shared is provided. Investigators are expected to update the data that they are collecting, the initial submission date and initial share dates. The NIMH Data Archive shares data when those dates are met.

  3. Submission Exemption — Those with Administrative or Submission Access to the Collection may request an exemption for submission for a defined period by stating the reason and timeframe. Note that the program officer on the grant may review this request.


Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.

For those with privileges to edit the collection, it is possible to upload your data definitions using this interface. NDA support staff will then follow up with a harmonized data definition for you to use in providing additional data.

Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Research Subject and Pedigree info iconApproved
Imaging (Structural, fMRI, DTI, PET, microscopy) info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.