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Frequently Asked Questions


NDA Help Center

Filter Cart

The Filter Cart provides a way to query and access data for which you may be interested.  There are multiple places to go query and Add to Filter Cart (Sometimes called Download).  

A few points related to the filter cart are important to understand with the NDA Query/Filter implementation: 

First, the filter cart is populated asyncronously.  So, when you add subjects, sometimes it may take a few minutes to populate.  You can continue to do other things during this time. 

When you are adding your first filter, all data associated with your query will be added to the filter cart (whether it be a collection, a concept, a study, a data structure/elment or subjects). Not all data available for the subjects selected will necessarily be displayed.  For example, if you select the NDA imaging structure image03, and further restrict that query to scan_type fMRI, only fMRI images will appear and only the image03 structure will be available.  However, if you want to see all of the clinical and phenotype, then select, "Find All Subject Data" to see all the data avaialble for those subjects.  

when a secord or third filter is applied, an AND condition is used to determine the subjects that are exist in all filters.  If the subject does not appear in any filter, that subjects data will be excluded from your filter cart. Given the sparcity of data in the NDA, it is possible for no subjects to appear across filters.  If that happens, clear your filter cart, and start over.  

The NDA is looking to enhance query/filtering.  Until additional tools become available, it is best to package more data than you need and then package and download the data and use other tools to further restrict and analyze the data.  If you have any questions on data access, are interested in using avaialble web services or need help accessing data, please contact us for assistance.  

Frequently Asked Questions



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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

Warning Notice

This is a U.S. Government computer system, which may be accessed and used only for authorized Government business by authorized personnel. Unauthorized access or use of this computer system may subject violators to criminal, civil, and/or administrative action. All information on this computer system may be intercepted, recorded, read, copied, and disclosed by and to authorized personnel for official purposes, including criminal investigations. Such information includes sensitive data encrypted to comply with confidentiality and privacy requirements. Access or use of this computer system by any person, whether authorized or unauthorized, constitutes consent to these terms. There is no right of privacy in this system.

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The filters you have selected from various query interfaces will be stored here, in the 'Filter Cart'. The database will be queried using filters added to your 'Filter Cart', when multiple filters are defined, each will be executed using 'AND' logic, so with each filter that is applied the result set gets smaller.

From the 'Filter Cart' you can inspect each of the filters that have been defined, and you also have the option to remove filters. The 'Filter Cart' itself will display the number of filters applied along with the number of subjects that are identified by the combination of those filters. For example a GUID filter with two subjects, followed by a GUID filter for just one of those subjects would return only data for the subject that is in both GUID filters.

If you have a question about the filter cart, or underlying filters please contact the help desk at The NDA Help Desk

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1 Numbers reported are subjects by age
New Trial
New Project

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

SelectExperiment IdExperiment NameExperiment Type
  • Select One
  • EEG
  • EGG
  • Eye Tracking
  • Omics
  • fMRI
Created On
953Shallow EpisodicfMRI06/20/2018
952Semantic EncodingfMRI06/20/2018
951Resting StatefMRI06/20/2018
949Resting StatefMRI06/18/2018
943Emotional Face TaskfMRI06/13/2018
941Meridians localizerfMRI06/07/2018
940V1 localizer movingDotsfMRI06/07/2018
938MT localizer dots movingDotsfMRI06/07/2018
937MT localizer gratings movingDotsfMRI06/07/2018
936V1 localizer peripheryfMRI06/07/2018
935Contrast peripheryfMRI06/07/2018
934MT localizer peripheryfMRI06/07/2018
933Pilot01: Posner Cueing with st-tACSEye Tracking06/06/2018
932Social- Theory of Mind Localizer TaskfMRI06/01/2018
931Faces TaskfMRI05/31/2018
929Moral RatingfMRI05/30/2018
928Pain Detection fMRI05/30/2018
927Reward TaskfMRI05/30/2018
926Go no Go TaskfMRI05/30/2018
924EARLI Placenta WGBSOmics05/24/2018
923Anxiety-CBT fMRI (pre-post) - Version 4 BlockfMRI05/15/2018
922Anxiety-CBT fMRI (pre-post) - Version 3 BlockfMRI05/15/2018
921Anxiety-CBT fMRI (pre-post) - Version 2 BlockfMRI05/15/2018
920Anxiety-CBT fMRI (pre-post) - Version 1 BlockfMRI05/15/2018
919Neural overlap in item representations across episodes impairs context memoryfMRI05/11/2018
918ReferenceTissue: U01MH106892_Brain_Amplicon_SeqOmics05/08/2018
914PFC analysis in bloodOmics04/27/2018
913Task and emotional content driven visual competitionfMRI04/27/2018
912Task and emotional content driven visual competitionEEG04/23/2018
911Resting StatefMRI04/20/2018
910Modified Monetary Incentive Delay fMRI04/20/2018
908Resting State Pre-Stress Visit 1fMRI04/20/2018
907Montreal Imaging Stress Task Visit 1fMRI04/18/2018
9062-back Post-Stress Visit 1fMRI04/18/2018
9051-back Post-Stress Visit 1fMRI04/18/2018
9040-back Post-Stress Visit 1fMRI04/18/2018
9032-back Pre-Stress Visit 1fMRI04/18/2018
9021-back Pre-Stress Visit 1fMRI04/18/2018
9010-back Pre-Stress Visit 1fMRI04/18/2018
899Investigating a Neurobehavioral Mechanism of Paranoia - Resting State ScansfMRI04/06/2018
Collection - Add Experiment
Add Supporting Documentation
Select File

Please enter the name of the data structure to search or if your definition does not exist, please upload that definition so that it can be appropriately defined for submission. Multiple data structures may be associated with a single Data Expected entry. Please add only one data structure per assessment.






You have requested to move the sharing dates for the following assessments:
Data Expected Item Original Sharing Date New Sharing Date

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Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

Funding Source

The ability to associate the funding source for the project is provided. For NIH funded grants, linkage to Project Reporter information (e.g. R01MH123456) is supported. Projects funded by others, including the URL of the project, are listed. Non NIH funded projects will become available here to link that data with the appropriate funding agency.

Supporting Documentation

Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Atypical Late Neurodevelopment in Autism
Janet E Lainhart, MD 
Longitudinal neuroimaging and neuropsychological study to understand how brain mechanisms and clinical phenotypes in autism are related.
Funding Completed
Loading Chart...
NIH - Extramural None

R01MH080826-01 Atypical Late Neurodevelopment in Autism: A Longitudinal MRI and DTI Study 08/01/2007 07/31/2013 172 172 UNIVERSITY OF UTAH $2,687,927.00
R01MH084795-01 The Microstructural Basis of Abnormal Connectivity in Autism 04/01/2009 01/31/2015 Not Reported Not Reported UNIVERSITY OF WISCONSIN-MADISON $1,854,399.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Aberrant Behavior Checklist (ABC) - Community Clinical Assessments 113
Autism Diagnostic Interview - Cumulative Clinical Assessments 90
Autism Diagnostic Observation Schedule (ADOS) - Module 4 Clinical Assessments 60
Autism Diagnostic Observation Schedule (ADOS)- Module 1 Clinical Assessments 11
Autism Diagnostic Observation Schedule (ADOS)- Module 2 Clinical Assessments 18
Autism Diagnostic Observation Schedule (ADOS)- Module 3 Clinical Assessments 58
CADS-P Clinical Assessments 120
CELF Preschool Clinical Assessments 21
CELF-3 Clinical Eval of Lang Fundamentals, 3th ed Clinical Assessments 93
CELF-4 Clinical Eval of Lang Fundamentals, 4th ed Clinical Assessments 29
Comprehensive Test of Phonological Processing (CTOPP) Clinical Assessments 113
DAS-II: Differential Ability Scales 2nd Ed. School Age Clinical Assessments 58
DAS-II:Differential Ability Scales 2nd Ed. Early Years Clinical Assessments 18
Developmental Behavior Checklist Clinical Assessments 55
Edinburgh Handedness Inventory Clinical Assessments 121
Expressive Vocabulary Test Clinical Assessments 27
Finger Tapping Test Clinical Assessments 106
Grooved Pegboard Test Clinical Assessments 106
Halstead-Reitan Grip Strength Clinical Assessments 106
Hooper Visual Organization Test (VOT) Clinical Assessments 81
Image Imaging 131
Mullen Scales of Early Learning Clinical Assessments 3
Screen for Child Anxiety Related Disorders (SCARED), Parent/Child Clinical Assessments 84
Social Responsiveness Scale (SRS) Clinical Assessments 96
Social Responsiveness Scale (SRS) - Adult/Self Version Clinical Assessments 46
Test of Memory and Learning (TOMAL) Clinical Assessments 110
Trail Making Test, Child and Adult Clinical Assessments 97
Vineland I Clinical Assessments 116
Wechsler Adult Intelligence Scale III Clinical Assessments 49
Wechsler Intelligence Scale for Children III Clinical Assessments 25
Wide Range Achievement Test 3 (WRAT3) Clinical Assessments 77

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
29728946Study (563)Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder.Journal of autism and developmental disordersPrigge MBD, Bigler ED, Travers BG, Froehlich A, Abildskov T, Anderson JS, Alexander AL, Lange N, Lainhart JE, Zielinski BAMay 2018Relevant
29251836Create StudyLongitudinal development of thalamic and internal capsule microstructure in autism spectrum disorder.Autism research : official journal of the International Society for Autism ResearchMclaughlin K, Travers BG, Dadalko OI, Dean DC, Tromp D, Adluru N, Destiche D, Freeman A, Prigge MD, Froehlich A, Duffield TC, Zielinski BA, Bigler ED, Lange N, Anderson JS, Alexander AL, Lainhart JEDecember 2017Not Determined
28966659Create StudyRelationship between brain stem volume and aggression in children diagnosed with autism spectrum disorder.Research in autism spectrum disordersLundwall RA, Stephenson KG, Neeley-Tass ES, Cox JC, South M, Bigler ED, Anderberg E, Prigge MD, Hansen BD, Lainhart JE, Kellems RO, Petrie JA, Gabrielsen TPFebruary 2017Not Determined
28291247Create StudyEnhancing studies of the connectome in autism using the autism brain imaging data exchange II.Scientific dataDi Martino A, O'Connor D, Chen B, Alaerts K, Anderson JS, Assaf M, Balsters JH, Baxter L, Beggiato A, Bernaerts S, Blanken LM, Bookheimer SY, Braden BB, Byrge L, Castellanos FX, Dapretto M, Delorme R, Fair DA, Fishman I, Fitzgerald J, Gallagher L, Keehn RJ, Kennedy DP, Lainhart JE, Luna B, et al.March 2017Not Relevant
28251191Create StudyApplications of Epsilon Radial Networks in Neuroimage Analyses.Advances in image and video technology : 5th Pacific Rim Symposium, PSIVT 2011, Gwangju, South Korea, November 20-23, 2011 : proceedings. IEEE Pacific Rim Symposium on Image and Video Technology (5th : 2011 : Gwangju, Korea)Adluru N, Chung MK, Lange NT, Lainhart JE, Alexander ALJanuary 2011Not Relevant
28138427Create StudyMultivariate characterization of white matter heterogeneity in autism spectrum disorder.NeuroImage. ClinicalDean DC, Lange N, Travers BG, Prigge MB, Matsunami N, Kellett KA, Freeman A, Kane KL, Adluru N, Tromp DP, Destiche DJ, Samsin D, Zielinski BA, Fletcher PT, Anderson JS, Froehlich AL, Leppert MF, Bigler ED, Lainhart JE, Alexander ALJanuary 2017Not Determined
28031999Create StudySleep duration and resting fMRI functional connectivity: examination of short sleepers with and without perceived daytime dysfunction.Brain and behaviorCurtis BJ, Williams PG, Jones CR, Anderson JSDecember 2016Not Determined
27061223Create StudyLongitudinal development of manual motor ability in autism spectrum disorder from childhood to mid-adulthood relates to adaptive daily living skills.Developmental scienceTravers BG, Bigler ED, Duffield TC, Prigge MD, Froehlich AL, Lange N, Alexander AL, Lainhart JEApril 7, 2016Not Determined
27021440Create StudyInvestigating the Microstructural Correlation of White Matter in Autism Spectrum Disorder.Brain connectivityDean DC, Travers BG, Adluru N, Tromp DO PM, Destiche DJ, Samsin D, Prigge MB, Zielinski BA, Fletcher PT, Anderson JS, Froehlich AL, Bigler ED, Lange N, Lainhart JE, Alexander ALJune 2016Not Determined
26744772Create StudyConfirmation of the Factor Structure and Measurement Invariance of the Children's Scale of Hostility and Aggression: Reactive/Proactive in Clinic-Referred Children With and Without Autism Spectrum Disorder.Journal of child and adolescent psychopharmacologyFarmer CA, Kaat AJ, Mazurek MO, Lainhart JE, Dewitt MB, Cook EH, Butter EM, Aman MGFebruary 2016Not Determined
26376476Create StudyGastroduodenal mucosal defense mechanisms.Current opinion in gastroenterologySaid H, Kaji I, Kaunitz JDNovember 2015Not Relevant
26292997Create StudyBeery VMI performance in autism spectrum disorder.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescenceGreen RR, Bigler ED, Froehlich A, Prigge MB, Travers BG, Cariello AN, Anderson JS, Zielinski BA, Alexander A, Lange N, Lainhart JEAugust 21, 2015Not Determined
26001365Create StudyBrainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism.Journal of autism and developmental disordersTravers, Brittany G; Bigler, Erin D; Tromp, Do P M; Adluru, Nagesh; Destiche, Dan; Samsin, Danica; Froehlich, Alyson; Prigge, Molly D B; Duffield, Tyler C; Lange, Nicholas; Alexander, Andrew L; Lainhart, Janet ESeptember 2015Not Determined
25951196Create StudyVariation in functional connectivity along anterior-to-posterior intraparietal sulcus, and relationship with age across late childhood and adolescence.Developmental cognitive neuroscienceVinette, Sarah A; Bray, SigneJune 2015Not Relevant
25871566Create StudyWIDE RANGE ACHIEVEMENT TEST IN AUTISM SPECTRUM DISORDER: TEST-RETEST STABILITY.Psychological reportsJantz, Paul B; Bigler, Erin D; Froehlich, Alyson L; Prigge, Molly B D; Cariello, Annahir N; Travers, Brittany G; Anderson, Jeffrey; Zielinski, Brandon A; Alexander, Andrew L; Lange, Nicholas; Lainhart, Janet EJune 2015Not Determined
25809403Create StudyAge-related changes in intrinsic function of the superior temporal sulcus in autism spectrum disorders.Social cognitive and affective neuroscienceAlaerts K, Nayar K, Kelly C, Raithel J, Milham MP, Di Martino AOctober 2015Not Determined
25774283Create StudyAtypical development of white matter microstructure of the corpus callosum in males with autism: a longitudinal investigation.Molecular autismTravers, Brittany G; Tromp, Do P M; Adluru, Nagesh; Lange, Nicholas; Destiche, Dan; Ennis, Chad; Nielsen, Jared A; Froehlich, Alyson L; Prigge, Molly B D; Fletcher, P Thomas; Anderson, Jeffrey S; Zielinski, Brandon A; Bigler, Erin D; Lainhart, Janet E; Alexander, Andrew L2015Not Determined
25749302Create StudyMesial temporal lobe and memory function in autism spectrum disorder: an exploration of volumetric findings.Journal of clinical and experimental neuropsychologyTrontel, Haley G; Duffield, Tyler C; Bigler, Erin D; Abildskov, Tracy J; Froehlich, Alyson; Prigge, Molly B D; Travers, Brittany G; Anderson, Jeffrey S; Zielinski, Brandon A; Alexander, Andrew L; Lange, Nicholas; Lainhart, Janet E2015Not Determined
25727858Create StudyMulticenter mapping of structural network alterations in autism.Human brain mappingValk, Sofie L; Di Martino, Adriana; Milham, Michael P; Bernhardt, Boris CJune 2015Not Relevant
25602243Create StudyBrain imaging research in autism spectrum disorders: in search of neuropathology and health across the lifespan.Current opinion in psychiatryLainhart, Janet EMarch 2015Not Relevant
25381736Create StudyLongitudinal volumetric brain changes in autism spectrum disorder ages 6-35 years.Autism research : official journal of the International Society for Autism ResearchLange, Nicholas; Travers, Brittany G; Bigler, Erin D; Prigge, Molly B D; Froehlich, Alyson L; Nielsen, Jared A; Cariello, Annahir N; Zielinski, Brandon A; Anderson, Jeffrey S; Fletcher, P Thomas; Alexander, Andrew A; Lainhart, Janet EFebruary 2015Not Determined
24954282Create StudyA functional network estimation method of resting-state fMRI using a hierarchical Markov random field.NeuroImageLiu W, Awate SP, Anderson JS, Fletcher PTOctober 15, 2014Not Determined
24761228Create StudyFusiform correlates of facial memory in autism.Behavioral sciences (Basel, Switzerland)Trontel HG, Duffield TC, Bigler ED, Froehlich A, Prigge MB, Nielsen JA, Cooperrider JR, Cariello AN, Travers BG, Anderson JS, Zielinski BA, Alexander A, Lange N, Lainhart JE2013Not Determined
24755274Create StudyLongitudinal changes in cortical thickness in autism and typical development.Brain : a journal of neurologyZielinski BA, Prigge MB, Nielsen JA, Froehlich AL, Abildskov TJ, Anderson JS, Fletcher PT, Zygmunt KM, Travers BG, Lange N, Alexander AL, Bigler ED, Lainhart JEJune 2014Not Determined
24684006Create StudyModel selection and estimation of multi-compartment models in diffusion MRI with a Rician noise model.Information processing in medical imaging : proceedings of the ... conferenceZhu X, Gur Y, Wang W, Fletcher PT2013Not Determined
24683999Create StudyA hierarchical geodesic model for diffeomorphic longitudinal shape analysis.Information processing in medical imaging : proceedings of the ... conferenceSingh N, Hinkle J, Joshi S, Fletcher PT2013Not Determined
24683981Create StudyJoint fractional segmentation and multi-tensor estimation in diffusion MRI.Information processing in medical imaging : proceedings of the ... conferenceHao X, Fletcher PT2013Not Determined
24683956Create StudyBayesian estimation of regularization and atlas building in diffeomorphic image registration.Information processing in medical imaging : proceedings of the ... conferenceZhang M, Singh N, Fletcher PT2013Not Determined
24497627Create StudyAggression in children with autism spectrum disorders and a clinic-referred comparison group.Autism : the international journal of research and practiceFarmer, Cristan; Butter, Eric; Mazurek, Micah O; Cowan, Charles; Lainhart, Janet; Cook, Edwin H; DeWitt, Mary Beth; Aman, MichaelApril 2015Not Relevant
24269298Create StudyLongitudinal processing speed impairments in males with autism and the effects of white matter microstructure.NeuropsychologiaTravers BG, Bigler ED, Tromp do PM, Adluru N, Froehlich AL, Ennis C, Lange N, Nielsen JA, Prigge MB, Alexander AL, Lainhart JEJanuary 2014Not Determined
24211814Create StudyImproved segmentation of white matter tracts with adaptive Riemannian metrics.Medical image analysisHao X, Zygmunt K, Whitaker RT, Fletcher PTJanuary 2014Not Relevant
24163728Create StudyEffects of DTI spatial normalization on white matter tract reconstructions.Proceedings of SPIE--the International Society for Optical EngineeringAdluru N, Zhang H, Tromp DP, Alexander ALMarch 13, 2013Not Determined
24163723Create StudyADAPTIVE CUTS FOR EXTRACTING SPECIFIC WHITE MATTER TRACTS.Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical ImagingAdluru N, Singh V, Alexander ALMay 5, 2012Not Relevant
24078018Create StudyUnderconnectivity of the superior temporal sulcus predicts emotion recognition deficits in autism.Social cognitive and affective neuroscienceAlaerts K, Woolley DG, Steyaert J, Di Martino A, Swinnen SP, Wenderoth NOctober 2014Not Determined
23985036Create StudyNeuropsychological investigation of motor impairments in autism.Journal of clinical and experimental neuropsychologyDuffield TC, Trontel HG, Bigler ED, Froehlich A, Prigge MB, Travers B, Green RR, Cariello AN, Cooperrider J, Nielsen J, Alexander A, Anderson J, Fletcher PT, Lange N, Zielinski B, Lainhart J2013Not Determined
23967180Create StudyAn evaluation of the left-brain vs. right-brain hypothesis with resting state functional connectivity magnetic resonance imaging.PloS oneNielsen JA, Zielinski BA, Ferguson MA, Lainhart JE, Anderson JS2013Not Determined
23774715Create StudyThe autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism.Molecular psychiatryDi Martino A, Yan CG, Li Q, Denio E, Castellanos FX, Alaerts K, Anderson JS, Assaf M, Bookheimer SY, Dapretto M, Deen B, Delmonte S, Dinstein I, Ertl-Wagner B, Fair DA, Gallagher L, Kennedy DP, Keown CL, Keysers C, Lainhart JE, Lord C, Luna B, Menon V, Minshew NJ, Monk CS, et al.June 2014Not Determined
23436773Create StudyLongitudinal Heschl's gyrus growth during childhood and adolescence in typical development and autism.Autism research : official journal of the International Society for Autism ResearchPrigge MD, Bigler ED, Fletcher PT, Zielinski BA, Ravichandran C, Anderson J, Froehlich A, Abildskov T, Papadopolous E, Maasberg K, Nielsen JA, Alexander AL, Lange N, Lainhart JApril 2013Not Determined
23397550Create StudyPenalized likelihood phenotyping: unifying voxelwise analyses and multi-voxel pattern analyses in neuroimaging: penalized likelihood phenotyping.NeuroinformaticsAdluru N, Hanlon BM, Lutz A, Lainhart JE, Alexander AL, Davidson RJApril 2013Not Determined
23316267Create StudyCosine series representation of 3D curves and its application to white matter fiber bundles in diffusion tensor imaging.Statistics and its interfaceChung MK, Adluru N, Lee JE, Lazar M, Lainhart JE, Alexander AL2010Not Determined
23185305Create StudyscMRI reveals large-scale brain network abnormalities in autism.PloS oneZielinski BA, Anderson JS, Froehlich AL, Prigge MB, Nielsen JA, Cooperrider JR, Cariello AN, Fletcher PT, Alexander AL, Lange N, Bigler ED, Lainhart JE2012Not Determined
23130086Create StudyCorpus Callosum Area in Children and Adults with Autism.Research in autism spectrum disordersPrigge MB, Lange N, Bigler ED, Merkley TL, Neeley ES, Abildskov TJ, Froehlich AL, Nielsen JA, Cooperrider JR, Cariello AN, Ravichandran C, Alexander AL, Lainhart JE2013Not Determined
22786754Create StudyDiffusion tensor imaging in autism spectrum disorder: a review.Autism research : official journal of the International Society for Autism ResearchTravers BG, Adluru N, Ennis C, Tromp do PM, Destiche D, Doran S, Bigler ED, Lange N, Lainhart JE, Alexander ALOctober 2012Not Determined
22432902Create StudyCharacterization of cerebral white matter properties using quantitative magnetic resonance imaging stains.Brain connectivityAlexander AL, Hurley SA, Samsonov AA, Adluru N, Hosseinbor AP, Mossahebi P, Tromp do PM, Zakszewski E, Field AS2011Not Determined
22291857Create StudyIntact Prototype Formation but Impaired Generalization in Autism.Research in autism spectrum disordersFroehlich AL, Anderson JS, Bigler ED, Miller JS, Lange NT, Dubray MB, Cooperrider JR, Cariello A, Nielsen JA, Lainhart JE2012Not Determined
22068999Create StudyIncreased neuron number and head size in autism.JAMALainhart JE, Lange NNovember 9, 2011Not Relevant
22006979Create StudyFunctional connectivity magnetic resonance imaging classification of autism.Brain : a journal of neurologyAnderson JS, Nielsen JA, Froehlich AL, DuBray MB, Druzgal TJ, Cariello AN, Cooperrider JR, Zielinski BA, Ravichandran C, Fletcher PT, Alexander AL, Bigler ED, Lange N, Lainhart JEDecember 2011Not Determined
21843004Create StudyMemory functioning in children and adolescents with autism.NeuropsychologySouthwick JS, Bigler ED, Froehlich A, Dubray MB, Alexander AL, Lange N, Lainhart JENovember 2011Not Determined
21803162Create StudyA diffusion tensor brain template for rhesus macaques.NeuroImageAdluru N, Zhang H, Fox AS, Shelton SE, Ennis CM, Bartosic AM, Oler JA, Tromp do PM, Zakszewski E, Gee JC, Kalin NH, Alexander ALJanuary 2, 2012Not Determined
21761642Create StudyAdaptive Riemannian metrics for improved geodesic tracking of white matter.Information processing in medical imaging : proceedings of the ... conferenceHao X, Whitaker RT, Fletcher PT2011Not Determined
21383324Create StudyA population-based study on the influence of brain atrophy on 20-year survival after age 85.NeurologyOlesen PJ, Guo X, Gustafson D, Börjesson-Hanson A, Sacuíu S, Eckerström C, Bigler ED, Skoog IMarch 8, 2011Not Determined
21182212Create StudyAtypical diffusion tensor hemispheric asymmetry in autism.Autism research : official journal of the International Society for Autism ResearchLange N, Dubray MB, Lee JE, Froimowitz MP, Froehlich A, Adluru N, Wright B, Ravichandran C, Fletcher PT, Bigler ED, Alexander AL, Lainhart JEDecember 2010Not Determined
20943668Create StudyDecreased interhemispheric functional connectivity in autism.Cerebral cortex (New York, N.Y. : 1991)Anderson JS, Druzgal TJ, Froehlich A, DuBray MB, Lange N, Alexander AL, Abildskov T, Nielsen JA, Cariello AN, Cooperrider JR, Bigler ED, Lainhart JEMay 2011Not Determined
20446134Create StudyAssociations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescents.Developmental neuropsychologyLange N, Froimowitz MP, Bigler ED, Lainhart JE, Brain Development Cooperative Group2010Not Determined
20446133Create StudyVolumetric and voxel-based morphometry findings in autism subjects with and without macrocephaly.Developmental neuropsychologyBigler ED, Abildskov TJ, Petrie JA, Johnson M, Lange N, Chipman J, Lu J, McMahon W, Lainhart JE2010Not Determined
20132894Create StudyMicrostructural connectivity of the arcuate fasciculus in adolescents with high-functioning autism.NeuroImageFletcher PT, Whitaker RT, Tao R, DuBray MB, Froehlich A, Ravichandran C, Alexander AL, Bigler ED, Lange N, Lainhart JEJuly 1, 2010Not Determined
19964408Create StudyAn experimental evaluation of diffusion tensor image segmentation using graph-cuts.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual ConferenceHan D, Singh V, Lee JE, Zakszewski E, Adluru N, Oakes TR, Alexander A2009Not Determined
19964040Create StudyClassification in DTI using shapes of white matter tracts.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual ConferenceAdluru N, Hinrichs C, Chung MK, Lee JE, Singh V, Bigler ED, Lange N, Lainhart JE, Alexander AL2009Not Determined
19963927Create StudyEfficient parametric encoding scheme for white matter fiber bundles.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual ConferenceChung MK, Adluru N, Lee JE, Lazar M, Lainhart JE, Alexander AL2009Not Determined
19749222Create StudyDecreased left posterior insular activity during auditory language in autism.AJNR. American journal of neuroradiologyAnderson JS, Lange N, Froehlich A, DuBray MB, Druzgal TJ, Froimowitz MP, Alexander AL, Bigler ED, Lainhart JEJanuary 2010Not Determined
19694302Create StudyA variational image-based approach to the correction of susceptibility artifacts in the alignment of diffusion weighted and structural MRI.Information processing in medical imaging : proceedings of the ... conferenceTao R, Fletcher PT, Gerber S, Whitaker RTJanuary 2009Not Determined
18976713Create StudyA study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis.NeuroImageLee JE, Chung MK, Lazar M, DuBray MB, Kim J, Bigler ED, Lainhart JE, Alexander ALFebruary 1, 2009Not Determined
18419839Create StudyQuantitative magnetic resonance image analysis of the cerebellum in macrocephalic and normocephalic children and adults with autism.Journal of the International Neuropsychological Society : JINSCleavinger HB, Bigler ED, Johnson JL, Lu J, McMahon W, Lainhart JEMay 2008Not Determined
17204387Create StudyQuantitative temporal lobe differences: autism distinguished from controls using classification and regression tree analysis.Brain & developmentNeeley ES, Bigler ED, Krasny L, Ozonoff S, McMahon W, Lainhart JEAugust 2007Not Determined

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
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Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Mullen Scales of Early Learning info iconApproved
Trail Making Test (Child and Adult) info iconApproved
Imaging (Structural, fMRI, DTI, PET, microscopy) info iconApproved
ABC Community info iconApproved
Beck Depression Inventory info iconApproved
Hooper Visual Organization Test info iconApproved
Wide Range Achievement Test info iconApproved
Social Responsiveness Scale (SRS) info iconApproved
Wechsler Abbreviated Scale of Intelligence (WASI) info iconApproved
Comprehensive Test of Phonological Processing (CTOPP) info iconApproved
Grooved Pegboard Test info iconApproved
ADOS info iconApproved
DSM IV Criteria info iconApproved
DAS-II: Differential Ability Scales info iconApproved
ADI-R info iconApproved
Finger Tapping Test info iconApproved
Screen for Childhood Anxiety Related Emotional Disorders (SCARED) info iconApproved
Halstead Reitan Grip Strength info iconApproved
Vineland (Parent and Caregiver) info iconApproved
Wechsler Adult Intelligence Scale info iconApproved
Research Subject and Pedigree info iconApproved
Physical Exam info iconApproved
Test of Memory and Learning (TOMAL) info iconApproved
Clinical Evaluation of Language Fundamentals (CELF) info iconApproved
Child Anxiety and Depression Scale - Parent (RCAD-P) info iconApproved
Wechsler Intelligence Scale for Children info iconApproved
Developmental Behavior Checklist info iconApproved
Expressive Vocabulary Test II (EVT II) info iconApproved
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Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
Unravelling the Collective Diagnostic Power Behind the Features in the Autism Diagnostic Observation ScheduleBackground: Autism is a group of heterogeneous disorders defined by deficits in social interaction and communication. Typically, diagnosis depends on the results of a behavioural examination called the Autism Diagnostic Observation Schedule (ADOS). Unfortunately, administration of the ADOS exam is time-consuming and requires a significant amount of expert intervention, leading to delays in diagnosis and access to early intervention programs. The diagnostic power of each feature in the ADOS exam is currently unknown. Our hypothesis is that certain features could be removed from the exam without a significant reduction in diagnostic accuracy, sensitivity or specificity. Objective: Determine the smallest subset of predictive features in ADOS module-1 (an exam variant for patients with minimal verbal skills). Methodology: ADOS module-1 datasets were acquired from the Autism Genetic Resource Exchange and the National Database for Autism Research. The datasets contained 2572 samples with the following labels: autism (1763), autism spectrum (513), and non-autism (296). The datasets were used as input to 4 different cost-sensitive classifiers in Weka (functional trees, LADTree, logistic model trees, and PART). For each classifier, a 10-fold cross validation was preformed and the number of predictive features, accuracy, sensitivity, and specificity was recorded. Results & Conclusion: Each classifier resulted in a reduction of the number of ADOS features required for autism diagnosis. The LADtree classifier was able to obtain the largest reduction, utilizing only 10 of 29 ADOS module-1 features (96.8% accuracy, 96.9% sensitivity, and 95.9% specificity). Overall, these results are a step towards a more efficient behavioural exam for autism diagnosis. 11/2172Secondary AnalysisShared
* Data not on individual level