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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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General

Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

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Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Impairments of Theory of Mind disrupt patterns of brain activity
Rebecca Saxe 
Humans think constantly about one another's thoughts, for example, in order to communicate, to teach, to learn from, to cooperate with, to compete with, and to deceive one another. This ability to fluently infer what others are thinking is impaired in individuals with Autism Spectrum Disorders (ASD), but the neural basis of this impairment is poorly understood. In particular, brain regions involved in thinking about other peoples thoughts are not reliably smaller or less active in individuals with ASD. This proposal will test the possibility that it is not reduced magnitude of activity, but disorganization of the pattern of activity, in these brain regions which leads to social impairments in ASD. We will test these two hypotheses about the function of ToM regions in adults with ASD, in three key areas of ToM: understanding others thoughts that are relevant for moral judgments (e.g. intentional vs accidental harm), for inferring emotions, and for effective communication. Since ASD is a developmental disorder, it is critical to understand the developmental trajectory of these brain regions as well as their end state. Consequently, we will also test these hypotheses in children aged 5-12 years. We will also test whether the selectivity or pattern of activation in ToM brain regions changes over development.
NDAR
Enrolling
Shared
$1,590,879.00
136
130
240
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NIH - Extramural None


R01MH096914-01 Impairments of Theory of Mind disrupt patterns of brain activity 08/10/2012 04/30/2017 130 240 MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,590,879.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
498VICREW07/18/2016ApprovedfMRI
354TASTI07/14/2015ApprovedfMRI
294FGE04/07/2015ApprovedfMRI
295EIB04/08/2015ApprovedfMRI
296DIS04/08/2015ApprovedfMRI

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Observation Schedule (ADOS) - Module 4 Clinical Assessments 3
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 4 Clinical Assessments 11
Autism Spectrum Quotient (AQ) Clinical Assessments 44
Image Imaging 135
Kaufman Brief Intelligence Test, 2nd Edition (KBIT-2) Clinical Assessments 20

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
26628642Create StudyWhen minds matter for moral judgment: intent information is neurally encoded for harmful but not impure acts.Social cognitive and affective neuroscienceChakroff A, Dungan J, Koster-Hale J, Brown A, Saxe R, Young LMarch 2016Not Determined
26589334Create StudyLocalizing Pain Matrix and Theory of Mind networks with both verbal and non-verbal stimuli.NeuroImageJacoby N, Bruneau E, Koster-Hale J, Saxe RFebruary 1, 2016Not Determined
26212878Create StudyNeural representations of emotion are organized around abstract event features.Current biology : CBSkerry AE, Saxe RAugust 3, 2015Not Determined
25429141Create StudyA common neural code for perceived and inferred emotion.The Journal of neuroscience : the official journal of the Society for NeuroscienceSkerry AE, Saxe RNovember 26, 2014Not Determined
24960530Create StudyThinking about seeing: perceptual sources of knowledge are encoded in the theory of mind brain regions of sighted and blind adults.CognitionKoster-Hale J, Bedny M, Saxe ROctober 2014Not Determined
24073267Create StudySimilar brain activation during false belief tasks in a large sample of adults with and without autism.PloS oneDufour N, Redcay E, Young L, Mavros PL, Moran JM, Triantafyllou C, Gabrieli JD, Saxe R2013Not Determined
24012000Create StudyTheory of mind: a neural prediction problem.NeuronKoster-Hale J, Saxe RSeptember 4, 2013Not Determined
23479657Create StudyDecoding moral judgments from neural representations of intentions.Proceedings of the National Academy of Sciences of the United States of AmericaKoster-Hale J, Saxe R, Dungan J, Young LLApril 2, 2013Not Determined
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Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
help.tab.dataexpected.addnew
Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Imaging (Structural, fMRI, DTI, PET, microscopy) info iconApproved
Kaufman Brief Intelligence Test info iconApproved
ADOS info iconApproved
Autistic Spectrum Quotient info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

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