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Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Gaze Modification Strategies for Toddlers with ASD
Frederick Shic 
Recent eye tracking studies have shown that 20 month old toddlers with autism spectrum disorders (ASD), as compared to typically developing (TD) and developmentally delayed(DD) toddlers, attend less to the shared activities of others1 as well as to faces trying to engage them using direct eye contact and childdirectedspeech2 (i.e. bids for dyadic engagement). Since attending to others, and especially their actions, is critically linked to both social skill development and observational learning, teaching toddlers and children with ASD normative strategies for viewing others and their activities may provide new opportunities for them to learn about their social world. This proposal initiates a highly novel line of research which uses adaptive eye tracking technology and nonadaptive perceptually augmented cues in order to help 20montholdtoddlers allocate their attention to people and their actions in a more typical fashion. The project will be conducted in two phases. In the first phase, normative gaze patterns will be collected from 1824month old typically developing (TD) toddlers (N=50) watching videos of actresses engaged in everyday activities, with an emphasis on scenarios incorporating bids for dyadic engagement and shared activities. In the second phase, 20montholdtoddlerswith a preliminary diagnosis of ASD will be shown videos in the following 3 conditions: (1) a nonadaptive cue condition (N=16), where perceptual enhancement will be employed at selected scene locations (e.g. increasing contrast or emphasizing motion) in order to maintain the viewers attention towards normative locations of scanning (2) an adaptive cue condition (N=16), where, as viewers deviate from the normative gaze pattern, the scene automatically redirects attention back towards the normative pattern by darkening or deemphasizing atypical locations on the scene and (3) a control condition (N=16), where toddlers will view the scenes without manipulation, as is shown to TD participants in the first phase. Manipulated blocks will be preceded and followed by dyadic bid scenes and activity scenes which will establish both baseline scanning patterns and the effects of gaze manipulation. Behavioral assessments will be employed before and after the eye tracking sessions in order to gauge the generalizability of any changes to visual scanning strategies. If successful, this study may point towards new methods for training attention towards social information in toddlers with ASD, and may also lead to new eye tracking paradigms that may be more sensitive to atypical patterns of attention.
Enrollment Completed
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NIH - Extramural None

R21MH102572-01 Gaze Modification Strategies for Toddlers with ASD 02/13/2014 01/31/2016 98 Not Reported YALE UNIVERSITY $457,875.00

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To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
577Gaze Modification Strategies01/06/2017ApprovedEye Tracking

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Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Observation Schedule (ADOS) - Module 1 (2007) Clinical Assessments 13
Autism Diagnostic Observation Schedule (ADOS) Toddler Clinical Assessments 19
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 1 Clinical Assessments 13
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Toddler Module Clinical Assessments 20
Medical History Clinical Assessments 46
Mullen Scales of Early Learning Clinical Assessments 58
NIMH Medical History Questionnaire Clinical Assessments 36
Research Subject Clinical Assessments 62
Vineland-II - Survey Form (2005) Clinical Assessments 33

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
27015716Create StudyEye Tracking as a Behavioral Biomarker for Psychiatric Conditions: The Road Ahead.Journal of the American Academy of Child and Adolescent PsychiatryShic FApril 2016Not Relevant

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Mullen Scales of Early Learning info iconApproved
Eye Tracking info iconApproved
Research Subject and Pedigree info iconApproved
Vineland (Parent and Caregiver) info iconApproved
Medical History info iconApproved
ADOS info iconApproved
Structure not yet defined

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Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.