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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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1 Numbers reported are subjects by age
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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SelectExperiment IdExperiment NameExperiment Type
  • Select One
  • EEG
  • EGG
  • Eye Tracking
  • Omics
  • fMRI
Created On
912Task and emotional content driven visual competitionEEG04/23/2018
911Resting StatefMRI04/20/2018
910Modified Monetary Incentive Delay fMRI04/20/2018
908Resting State Pre-Stress Visit 1fMRI04/20/2018
907Montreal Imaging Stress Task Visit 1fMRI04/18/2018
9062-back Post-Stress Visit 1fMRI04/18/2018
9051-back Post-Stress Visit 1fMRI04/18/2018
9040-back Post-Stress Visit 1fMRI04/18/2018
9032-back Pre-Stress Visit 1fMRI04/18/2018
9021-back Pre-Stress Visit 1fMRI04/18/2018
9010-back Pre-Stress Visit 1fMRI04/18/2018
900DTIfMRI04/11/2018
899Investigating a Neurobehavioral Mechanism of Paranoia - Resting State ScansfMRI04/06/2018
898FAST-POMAfMRI04/03/2018
897parvizi_eeg_109EEG03/19/2018
896parvizi_eeg_107EEG03/19/2018
895parvizi_eeg_106EEG03/19/2018
894Dot ProbeEye Tracking03/07/2018
893Startle Habituation and Shock Sensitivity EvaluationEEG03/03/2018
892NPU EEG Task EEG03/03/2018
891Duke ACE ETEye Tracking03/02/2018
888Emotion 1.1 Determining context effects during potential threatfMRI02/26/2018
886RestfMRI02/14/2018
885SARTfMRI02/14/2018
884Plasma metabolic profileOmics02/05/2018
878Social Challenge AssessmentEye Tracking01/26/2018
877PRV-005-EEGEEG01/22/2018
876Mixed Anti and Pro (vgs) saccade mixed blocked (EyeTracking)Eye Tracking01/22/2018
875Attention modulation taskEye Tracking01/17/2018
874ruthldopa resting 17 and 18fMRI01/16/2018
873ruthldopa resting 15 and 16fMRI01/16/2018
872ruthldopa resting 13 and 14fMRI01/16/2018
871ruthldopa resting 11 and 12fMRI01/16/2018
870Resting State fMRIfMRI01/12/2018
869cyberballfMRI01/12/2018
868MDD_PilotfMRI01/12/2018
867Velten Mood Induction State-ItemfMRI01/12/2018
866Emotional Hemifield Task (EHT)EEG01/12/2018
865Genome EditingOmics01/12/2018
864parvizi_eeg_118EEG01/12/2018
863parvizi_eeg_117EEG01/12/2018
862parvizi_eeg_116EEG01/12/2018
861parvizi_eeg_115EEG01/12/2018
860parvizi_eeg_114EEG01/12/2018
859parvizi_eeg_113EEG01/12/2018
858PRV-003-EEGEEG01/12/2018
857PRV-004-EEGEEG01/12/2018
856PRV-007-EEGEEG01/12/2018
855Regulating Emotional Responses to Visual Images Across the Affective Instability SpectrumfMRI01/12/2018
854PRV-002-EEGEEG01/12/2018
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Shared

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

General

Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

Funding Source

The ability to associate the funding source for the project is provided. For NIH funded grants, linkage to Project Reporter information (e.g. R01MH123456) is supported. Projects funded by others, including the URL of the project, are listed. Non NIH funded projects will become available here to link that data with the appropriate funding agency.

Supporting Documentation

Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Early Quantitative Characterization of Reciprocal Social Behavior
John Constantino 
This project is focused on the development, validation, and standardization of quantitative methods to measure core components of variation in the social development of young children.This is critical for understanding autism and will inform the development and evaluation of early interventions for children with autism and related conditions. The proposed application covers the 18 to 48 month age range; i.e. the period when autism is actually first diagnosed. Currently, there exist few options for the tracking of autistic severity over time in this age range, few methods that allow severity trajectories to be reliably associated with candidate genetic and neurobiologic correlates of autistic impairment, and few established methods for making meaningful baseline measurements against which to quantify the impact of early intervention for young children with autism spectrum disorders (ASD). In this application, as we attempt to extend to early childhood a measurement system rooted in the ascertainment of quantitative autistic traits, we couple such measurements with laboratory assessment of visual social engagement (VSE), a fundamental parameter of human social development, whose origins are traceable to earliest infancy and whose implications are wide-ranging with respect to all aspects of early human social development. The specific aims are as follows: 1) To examine the general population distribution and longitudinal course of quantitative variation in reciprocal social behavior (and related indices of social behavioral development) in an ethnically diverse sample of preschool age twins (n=420 pairs), assessed prospectively at key ages within the interval from 18-48 months; 2) To examine stability and change in the same set of quantitative measures when implemented among children with ASD (n=90) first diagnosed at 18-24 months,and to clarify the relationship between these measures and traditional diagnostic assessments for ASD; 3) To examine variation in visual social engagement (VSE) among preschool children (125 general population twin pairs and 75 clinical ASD subjects) representing the entire range of social variation that occurs in nature.
NDAR
Enrolling
Shared
$2,727,277.00
2,063
4498
2636
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NIH - Extramural None


R01HD068479-01 Early Quantitative Characterization of Reciprocal Social Behavior 08/01/2012 04/30/2018 4498 2636 WASHINGTON UNIVERSITY $2,727,277.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

M-CHAT Clinical Assessments 986
MacArthur-Bates CDI - Words and Gestures Form Clinical Assessments 671
Research Subject Clinical Assessments 2063
Video-Referenced Ratings of Reciprocal Social Behavior Clinical Assessments 1037

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
29546561Create StudyEarly Origins of Autism Comorbidity: Neuropsychiatric Traits Correlated in Childhood Are Independent in Infancy.Journal of abnormal child psychologyMarch 16, 2018Not Determined
28700580Create StudyInfant viewing of social scenes is under genetic control and is atypical in autism.NatureConstantino JN, Kennon-Mcgill S, Weichselbaum C, Marrus N, Haider A, Glowinski AL, Gillespie S, Klaiman C, Klin A, Jones WJuly 2017Relevant
26497771Create StudyDiagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression.The Lancet. NeurologyConstantino JN, Charman TMarch 2016Not Relevant
25677414Create StudyRapid video-referenced ratings of reciprocal social behavior in toddlers: a twin study.Journal of child psychology and psychiatry, and allied disciplinesMarrus N, Glowinski AL, Jacob T, Klin A, Jones W, Drain CE, Holzhauer KE, Hariprasad V, Fitzgerald RT, Mortenson EL, Sant SM, Cole L, Siegel SA, Zhang Y, Agrawal A, Heath AC, Constantino JNDecember 2015Relevant
24019124Create StudyConfirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the social responsiveness scale-2.Autism : the international journal of research and practiceFrazier TW, Ratliff KR, Gruber C, Zhang Y, Law PA, Constantino JNJanuary 2014Not Relevant
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Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
28700580Create StudyInfant viewing of social scenes is under genetic control and is atypical in autism.NatureConstantino JN, Kennon-Mcgill S, Weichselbaum C, Marrus N, Haider A, Glowinski AL, Gillespie S, Klaiman C, Klin A, Jones WJuly 2017
25677414Create StudyRapid video-referenced ratings of reciprocal social behavior in toddlers: a twin study.Journal of child psychology and psychiatry, and allied disciplinesMarrus N, Glowinski AL, Jacob T, Klin A, Jones W, Drain CE, Holzhauer KE, Hariprasad V, Fitzgerald RT, Mortenson EL, Sant SM, Cole L, Siegel SA, Zhang Y, Agrawal A, Heath AC, Constantino JNDecember 2015
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Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Video-Referenced Ratings of Reciprocal Social Behavior info iconApproved
MacArthur Bates Communicative Development Inventory info iconApproved
M-CHAT info iconApproved
Research Subject and Pedigree info iconApproved
Social Responsiveness Scale (SRS) info iconApproved
Child Behavior Checklist (CBCL) info iconApproved
Brief Infant Toddle Social and Emotional Assessment info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
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