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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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The filters you have selected from various query interfaces will be stored here, in the 'Filter Cart'. The database will be queried using filters added to your 'Filter Cart', when multiple filters are defined, each will be executed using 'AND' logic, so with each filter that is applied the result set gets smaller.

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1 Numbers reported are subjects by age
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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Please enter the name of the data structure to search or if your definition does not exist, please upload that definition so that it can be appropriately defined for submission. Multiple data structures may be associated with a single Data Expected entry. Please add only one data structure per assessment.

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Data Expected Item Original Sharing Date New Sharing Date

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Shared

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

General

Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

Funding Source

The ability to associate the funding source for the project is provided. For NIH funded grants, linkage to Project Reporter information (e.g. R01MH123456) is supported. Projects funded by others, including the URL of the project, are listed. Non NIH funded projects will become available here to link that data with the appropriate funding agency.

Supporting Documentation

Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
The neurophysiology of sensory processing and multisensory integration in ASD
Natalie Russo 
Sensory atypicalities represent a cardinal feature of Autism Spectrum Disorders (ASD) and have beenestablished as the source of much behavioral aggression, frustration, and functional impairment overthe course of the lifespan within this population[1-3]. Research in this area generally has been clinicallyfocused, and limited to descriptions of the phenomena [4-8], although there are notable exceptions.These include a small number of psychophysics studies that report that, compared with neurotypicalindividuals, persons with ASD demonstrate a specific strength in their ability to detect small changes ordifferences between visual [9-14], auditory [15-21] and tactile stimuli [22-25]. In addition, emergingevidence from the basic neuroscience literature on distinguishing features of ASD highlightsfundamental differences in the reliability of evoked responses to unisensory stimuli using fMRI [26], aswell as differences in the timing [27, 28] and amount of multisensory integration [27, 29] using eventrelatedpotentials (ERP). Although both perspectives have advanced our knowledge of the field, whathas been missing from the current literatures but which is now the focus of this proposal, is anintegrated perspective on sensory processing in ASD. The series of studies proposed seeks to a)characterize the neurophysiological underpinnings of enhanced sensory perception across sensorymodalities in ASD, b) assess the impact of enhanced sensory perception on the ability to integrateinputs from multiple sensory modalities at the level of both behavior and brain, c) to trace how thesephenomenon unfold during development, d) to discern how attention shapes MSI in persons with anASD, e) to ascertain if physiological indices of sensory processing and MSI can predict autisticsymptomatology, and f) to determine if meaningful subgroups of individuals with ASD can beidentified on the basis of the physiological and behavioral data. These goals will be addressed in 14experiments in which the performance of individuals with an ASD (children and adults) will becompared to IQ- and age-matched typically developing children and adults. Children between the agesof 8 and 16 years, and adults age 18-30 will be tested to assess the developmental progression ofsensory processing and MSI both in TD and ASD individuals from the school years into adulthood. Bycombining clinical (diagnostic, cognitive and behavioral) and experimental (psychophysics, reactiontime, electrophysiology) methods to trace the development of sensory and multisensory processing andtheir relevance to clinical features of ASD, the proposed studies will yield evidence that is both clinicallyand functionally relevant. These findings may help identify physiological mechanisms that afford anintegrated perspective on ASD and facilitate early objective diagnosis.
NDAR
Enrolling
Shared
$1,667,827.00
93
270
100
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NIH - Extramural None


R01MH101536-01 The neurophysiology of sensory processing and multisensory integration in ASD 09/01/2013 08/31/2018 270 100 SYRACUSE UNIVERSITY $1,667,827.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Interview, Revised (ADI-R) Clinical Assessments 17
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 2 Clinical Assessments 1
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 3 Clinical Assessments 15
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 4 Clinical Assessments 10
Autism Spectrum Quotient (AQ) Clinical Assessments 67
BASC Parent Rating Scale Adolescent Clinical Assessments 32
BASC Parent Rating Scale Child Clinical Assessments 29
BASC Self Report Adolescent Clinical Assessments 27
BASC Self Report Child Clinical Assessments 18
EEG Form Imaging 44
Peabody Picture Vocabulary Test, Fourth Edition-Form B Clinical Assessments 67
Sensory Profile Adult Clinical Assessments 36
Sensory Profile Caregiver Clinical Assessments 41
Sensory Profile Short 2 Clinical Assessments 21
Social Communication Questionnaire (SCQ) - Current Form Clinical Assessments 27
Social Communication Questionnaire (SCQ) - Lifetime Clinical Assessments 25
Vineland-II - Parent and Caregiver Rating Form (2005) Clinical Assessments 58
WASI-2 Clinical Assessments 69

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
28032434Create StudyAdults blink more deeply: a comparative study of the attentional blink across different age groups.Developmental scienceRusso N, Kates WR, Shea N, Leblanc M, Wyble BDecember 2016Not Determined
27562676Create StudyMultisensory integration of redundant trisensory stimulation.Attention, perception & psychophysicsHagmann CE, Russo NNovember 2016Not Determined
26801777Create StudyChildren with Autism Detect Targets at Very Rapid Presentation Rates with Similar Accuracy as Adults.Journal of autism and developmental disordersHagmann CE, Wyble B, Shea N, LeBlanc M, Kates WR, Russo NJanuary 22, 2016Not Determined
help.tab.dataexpected

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
help.tab.dataexpected.addnew
Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Peabody Picture Vocabulary Test, Fourth Edition info iconApproved
Vineland (Parent and Caregiver) info iconApproved
Sensory Profile info iconApproved
Wechsler Abbreviated Scale of Intelligence (WASI) info iconApproved
Autistic Spectrum Quotient info iconApproved
Social Communication Questionnaire (SCQ) info iconApproved
Behavior Assessment System for Children (BASC) info iconApproved
Research Subject and Pedigree info iconApproved
ADOS info iconApproved
ADI-R info iconApproved
ERP info iconApproved
Psychophysics Experiments Form info iconApproved
EEG info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

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