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1 Numbers reported are subjects by age
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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SelectExperiment IdExperiment NameExperiment Type
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  • EEG
  • EGG
  • Eye Tracking
  • Omics
  • fMRI
Created On
911Resting StatefMRI04/20/2018
910Modified Monetary Incentive Delay fMRI04/20/2018
908Resting State Pre-Stress Visit 1fMRI04/20/2018
907Montreal Imaging Stress Task Visit 1fMRI04/18/2018
9062-back Post-Stress Visit 1fMRI04/18/2018
9051-back Post-Stress Visit 1fMRI04/18/2018
9040-back Post-Stress Visit 1fMRI04/18/2018
9032-back Pre-Stress Visit 1fMRI04/18/2018
9021-back Pre-Stress Visit 1fMRI04/18/2018
9010-back Pre-Stress Visit 1fMRI04/18/2018
899Investigating a Neurobehavioral Mechanism of Paranoia - Resting State ScansfMRI04/06/2018
894Dot ProbeEye Tracking03/07/2018
893Startle Habituation and Shock Sensitivity EvaluationEEG03/03/2018
892NPU EEG Task EEG03/03/2018
891Duke ACE ETEye Tracking03/02/2018
888Emotion 1.1 Determining context effects during potential threatfMRI02/26/2018
884Plasma metabolic profileOmics02/05/2018
878Social Challenge AssessmentEye Tracking01/26/2018
876Mixed Anti and Pro (vgs) saccade mixed blocked (EyeTracking)Eye Tracking01/22/2018
875Attention modulation taskEye Tracking01/17/2018
874ruthldopa resting 17 and 18fMRI01/16/2018
873ruthldopa resting 15 and 16fMRI01/16/2018
872ruthldopa resting 13 and 14fMRI01/16/2018
871ruthldopa resting 11 and 12fMRI01/16/2018
870Resting State fMRIfMRI01/12/2018
867Velten Mood Induction State-ItemfMRI01/12/2018
866Emotional Hemifield Task (EHT)EEG01/12/2018
865Genome EditingOmics01/12/2018
855Regulating Emotional Responses to Visual Images Across the Affective Instability SpectrumfMRI01/12/2018
853R61 Ezogabine Resting State FMRIfMRI01/11/2018
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Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Yale Autism Center of Excellence: Mechanisms of Social Engagement in the Autism Spectrum Disorders
Fred Volkmar 
The Yale ACE consists of 5 project areas and 3 core resources. Projects I, II, and III focus on the same cohort of 12- to 24-month old infants with ASD followed up longitudinally. Project IV involves structural and functional neuroimaging protocols on a group of 10-year-olds with ASD who were extensively characterized at the age of 2 and 4 years. Project V includes cytogenetic studies of the infants evaluated in Projects I, II, and III, and the ASD children evaluated in Project IV. The Administrative Core is charged with planning, oversight, and management of the Yale ACE. The Assessment Core ensures that all project areas have access to well-characterized patients, family members and control populations, from a behavioral/phenotypic standpoint and from a medical/pediatric and genetics standpoint. The Data Management and Analysis provides data management and data analytic expertise across projects.
Funding Completed
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NIH - Extramural None

P50MH081756-01 Mechanisms of Social Engagement in Autism Spectrum Disorders 04/01/2008 03/31/2013 1120 716 YALE UNIVERSITY $12,080,414.00

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To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
165Caregiver stimuli09/19/2014ApprovedEye Tracking

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Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Interview, Revised (ADI-R) Clinical Assessments 129
Autism Diagnostic Observation Schedule (ADOS)- Module 1 Clinical Assessments 144
Autism Diagnostic Observation Schedule (ADOS)- Module 2 Clinical Assessments 63
Autism Diagnostic Observation Schedule (ADOS)- Module 3 Clinical Assessments 20
CHARGE Family Characteristics Questionnaire Clinical Assessments 169
CHARGE Medical History Clinical Assessments 175
CHARGE Physical Exam Clinical Assessments 90
CSBS DP Behavior Sample Clinical Assessments 195
DAS-II: Differential Ability Scales 2nd Ed. School Age Clinical Assessments 14
DAS-II:Differential Ability Scales 2nd Ed. Early Years Clinical Assessments 4
Eye Tracking Subject-Experiment Imaging 122
Intervention History Full Version Clinical Assessments 131
Karyotype Clinical Assessments 98
MacArthur-Bates CDI - Words and Gestures Form Clinical Assessments 157
MacArthur-Bates CDI - Words and Sentences Form Clinical Assessments 59
Modified CHARGE Family Medical History (2007) Clinical Assessments 143
Modified CHARGE Family Medical History (rev July 2007) Clinical Assessments 49
Mullen Scales of Early Learning Clinical Assessments 194
NIMH Medical History Questionnaire Clinical Assessments 166
Preschool Language Scale, Fourth Edition (PLS-4) Clinical Assessments 103
Social Communication Questionnaire (SCQ) - Current Form Clinical Assessments 2
Social Communication Questionnaire (SCQ) - Lifetime Clinical Assessments 21
Social Responsiveness Scale (SRS) - Adult/Self Version Clinical Assessments 33
Vineland-II - Parent and Caregiver Rating Form (2005) Clinical Assessments 49
Vineland-II - Survey Form (2005) Clinical Assessments 141

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
28317113Create StudyTemperamental markers in toddlers with autism spectrum disorder.Journal of child psychology and psychiatry, and allied disciplinesMacari SL, Koller J, Campbell DJ, Chawarska KMarch 2017Not Determined
27855484Create StudyMechanisms of Diminished Attention to Eyes in Autism.The American journal of psychiatryMoriuchi JM, Klin A, Jones WJanuary 2017Not Determined
27289132Create StudyThe relationship between autism symptoms and arousal level in toddlers with autism spectrum disorder, as measured by electrodermal activity.Autism : the international journal of research and practicePrince EB, Kim ES, Wall CA, Gisin E, Goodwin MS, Simmons ES, Chawarska K, Shic FMay 2017Not Determined
27015716Create StudyEye Tracking as a Behavioral Biomarker for Psychiatric Conditions: The Road Ahead.Journal of the American Academy of Child and Adolescent PsychiatryShic FApril 2016Not Relevant
26903251Create StudyProspective Longitudinal Studies of Infant Siblings of Children With Autism: Lessons Learned and Future Directions.Journal of the American Academy of Child and Adolescent PsychiatrySzatmari P, Chawarska K, Dawson G, Georgiades S, Landa R, Lord C, Messinger DS, Thurm A, Halladay AMarch 2016Not Relevant
26682668Create StudyMultilevel Differences in Spontaneous Social Attention in Toddlers With Autism Spectrum Disorder.Child developmentChawarska K, Ye S, Shic F, Chen LMarch 2016Not Determined
26506589Create StudyIn Reply.Journal of the American Academy of Child and Adolescent PsychiatryChawarska K, Chang J, Campbell DNovember 2015Not Relevant
26264996Create StudyExamining the phenotypic heterogeneity of early Autism Spectrum Disorder: subtypes and short-term outcomes.Journal of child psychology and psychiatry, and allied disciplinesKim SH, Macari S, Koller J, Chawarska KAugust 12, 2015Not Determined
25457930Create Study18-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: a baby siblings research consortium study.Journal of the American Academy of Child and Adolescent PsychiatryChawarska K, Shic F, Macari S, Campbell DJ, Brian J, Landa R, Hutman T, Nelson CA, Ozonoff S, Tager-Flusberg H, Young GS, Zwaigenbaum L, Cohen IL, Charman T, Messinger DS, Klin A, Johnson S, Bryson SDecember 2014Not Determined
25398893Create StudyInterest level in 2-year-olds with autism spectrum disorder predicts rate of verbal, nonverbal, and adaptive skill acquisition.Autism : the international journal of research and practiceKlintwall L, Macari S, Eikeseth S, Chawarska KNovember 2015Not Determined
25245350Create StudyEarly generalized overgrowth in autism spectrum disorder: prevalence rates, gender effects, and clinical outcomes.Journal of the American Academy of Child and Adolescent PsychiatryCampbell DJ, Chang J, Chawarska KOctober 2014Not Determined
23954107Create StudySpeech disturbs face scanning in 6-month-old infants who develop autism spectrum disorder.Biological psychiatryShic F, Macari S, Chawarska KFebruary 1, 2014Not Determined
23877749Create StudyGaze response to dyadic bids at 2 years related to outcomes at 3 years in autism spectrum disorders: a subtyping analysis.Journal of autism and developmental disordersCampbell DJ, Shic F, Macari S, Chawarska KFebruary 2014Not Determined
23468071Create StudySystematic review and meta-analysis of pharmacological treatment of the symptoms of attention-deficit/hyperactivity disorder in children with pervasive developmental disorders.Journal of autism and developmental disordersReichow B, Volkmar FR, Bloch MHOctober 2013Not Determined
23160490Create StudySomatic copy number mosaicism in human skin revealed by induced pluripotent stem cells.NatureAbyzov A, Mariani J, Palejev D, Zhang Y, Haney MS, Tomasini L, Ferrandino AF, Rosenberg Belmaker LA, Szekely A, Wilson M, Kocabas A, Calixto NE, Grigorenko EL, Huttner A, Chawarska K, Weissman S, Urban AE, Gerstein M, Vaccarino FMDecember 20, 2012Not Determined
23062302Create StudyLexical decision as an endophenotype for reading comprehension: an exploration of an association.Development and psychopathologyNaples A, Katz L, Grigorenko ELNovember 2012Not Determined
22984058Create StudyNeuroscience. The emerging biology of autism spectrum disorders.Science (New York, N.Y.)State MW, Šestan NSeptember 14, 2012Not Determined
22612543Create StudyReading and a diffusion model analysis of reaction time.Developmental neuropsychologyNaples A, Katz L, Grigorenko EL2012Not Determined
22449643Create StudySensitivity and specificity of proposed DSM-5 diagnostic criteria for autism spectrum disorder.Journal of the American Academy of Child and Adolescent PsychiatryMcPartland JC, Reichow B, Volkmar FRApril 2012Not Determined
22428993Create StudyContext modulates attention to social scenes in toddlers with autism.Journal of child psychology and psychiatry, and allied disciplinesChawarska K, Macari S, Shic FAugust 2012Not Determined
22267520Create StudyAutistic traits are associated with diminished neural response to affective touch.Social cognitive and affective neuroscienceVoos AC, Pelphrey KA, Kaiser MDApril 2013Not Determined
22160686Create StudyInhibition of eye blinking reveals subjective perceptions of stimulus salience.Proceedings of the National Academy of Sciences of the United States of AmericaShultz S, Klin A, Jones WDecember 27, 2011Not Determined
22123582Create StudyDifferential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents.Development and psychopathologyNaumova OY, Lee M, Koposov R, Szyf M, Dozier M, Grigorenko ELFebruary 2012Not Determined
22057879Create StudyPractitioner's guide to assessment of autism spectrum disorders in infants and toddlers.Journal of autism and developmental disordersSteiner AM, Goldsmith TR, Snow AV, Chawarska KJune 2012Not Relevant
21969460Create StudyEarly generalized overgrowth in boys with autism.Archives of general psychiatryChawarska K, Campbell D, Chen L, Shic F, Klin A, Chang JOctober 2011Not Determined
21573835Create StudyAdaptive behavior in toddlers under two with autism spectrum disorders.Journal of autism and developmental disordersPaul R, Loomis R, Chawarska KFebruary 2014Not Determined
21567256Create StudyEarly-emerging social adaptive skills in toddlers with autism spectrum disorders: an item analysis.Journal of autism and developmental disordersVentola P, Saulnier CA, Steinberg E, Chawarska K, Klin AFebruary 2014Not Determined
21373955Create StudyBrief report: face-specific recognition deficits in young children with autism spectrum disorders.Journal of autism and developmental disordersBradshaw J, Shic F, Chawarska KOctober 2011Not Determined
21308998Create StudyPhonology and vocal behavior in toddlers with autism spectrum disorders.Autism research : official journal of the International Society for Autism ResearchSchoen E, Paul R, Chawarska KJune 2011Not Determined
21133549Create StudyCross-informant symptoms from CBCL, TRF, and YSR: trait and method variance in a normative sample of Russian youths.Psychological assessmentGrigorenko EL, Geiser C, Slobodskaya HR, Francis DJDecember 2010Not Determined
21129365Create StudyLimited activity monitoring in toddlers with autism spectrum disorder.Brain researchShic F, Bradshaw J, Klin A, Scassellati B, Chawarska KMarch 22, 2011Not Determined
21106717Create StudyCharacterizing and predicting outcomes of communication delays in infants and toddlers: implications for clinical practice.Language, speech, and hearing services in schoolsPaul R, Roth FPJuly 2011Not Determined
21039489Create StudyOut of the mouths of babes: vocal production in infant siblings of children with ASD.Journal of child psychology and psychiatry, and allied disciplinesPaul R, Fuerst Y, Ramsay G, Chawarska K, Klin AMay 2011Not Determined
20852731Create StudyDifferentiating ASD from DLD in Toddlers.Perspectives on language learning and educationPaul R, Chawarska K, Volkmar FOctober 1, 2008Not Determined
20124117Create StudyLimited attentional bias for faces in toddlers with autism spectrum disorders.Archives of general psychiatryChawarska K, Volkmar F, Klin AFebruary 2010Not Determined
20101452Create StudyTeaching children with autism to read for meaning: challenges and possibilities.Journal of autism and developmental disordersRandi J, Newman T, Grigorenko ELJuly 2010Not Determined
19953194Create StudyPathogenesis of autism: a patchwork of genetic causes.Future neurologyGrigorenko EL2009Not Determined
19594835Create StudyA prospective study of toddlers with ASD: short-term diagnostic and cognitive outcomes.Journal of child psychology and psychiatry, and allied disciplinesChawarska K, Klin A, Paul R, Macari S, Volkmar FOctober 2009Not Determined
19590943Create StudyLooking but not seeing: atypical visual scanning and recognition of faces in 2 and 4-year-old children with autism spectrum disorder.Journal of autism and developmental disordersChawarska K, Shic FDecember 2009Not Determined
19360656Create StudyLanguage outcomes of toddlers with autism spectrum disorders: a two year follow-up.Autism research : official journal of the International Society for Autism ResearchPaul R, Chawarska K, Cicchetti D, Volkmar FApril 2008Not Determined
19337577Create StudyProduction of Syllable Stress in Speakers with Autism Spectrum Disorders.Research in autism spectrum disordersPaul R, Bianchi N, Augustyn A, Klin A, Volkmar FJanuary 1, 2008Not Determined
18778978Create StudyThree things to remember if you are a functional magnetic resonance imaging researcher of face processing in autism spectrum disorders.Biological psychiatryKlin AOctober 1, 2008Not Determined
18458791Create StudyAutism in infants: an update.World psychiatry : official journal of the World Psychiatric Association (WPA)Volkmar FR, Chawarska KFebruary 2008Not Relevant
17286849Create StudyImpairments in monkey and human face recognition in 2-year-old toddlers with Autism Spectrum Disorder and Developmental Delay.Developmental scienceChawarska K, Volkmar FMarch 2007Not Determined
16806106Create StudyPlacental trophoblast inclusions in autism spectrum disorder.Biological psychiatryAnderson GM, Jacobs-Stannard A, Chawarska K, Volkmar FR, Kliman HJFebruary 15, 2007Not Determined

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Mullen Scales of Early Learning info iconApproved
Vineland (Parent and Caregiver) info iconApproved
ADI-R info iconApproved
Social Responsiveness Scale (SRS) info iconApproved
Research Subject and Pedigree info iconApproved
Physical Exam info iconApproved
Preschool Language Scale (PLS) info iconApproved
DAS-II: Differential Ability Scales info iconApproved
ADOS info iconApproved
Imaging (Structural, fMRI, DTI, PET, microscopy) info iconApproved
genomics/omics info iconApproved
ABC Community info iconApproved
Leiter International Performance Scale-Revised (Leiter-R) info iconApproved
Genetic Test info iconApproved
Social Communication Questionnaire (SCQ) info iconApproved
MacArthur Bates Communicative Development Inventory info iconApproved
Repetitive Behavior Scale - Revised (RBS-R) info iconApproved
Dysmorphology Exam info iconApproved
Intervention History info iconApproved
Medical History info iconApproved
Clinical Evaluation of Language Fundamentals (CELF) info iconApproved
Victoria-Yale Face Processing Battery info iconApproved
Communication and Symbolic Behavior Scales (CSBS) info iconApproved
Reynell Developmental Language Scales info iconApproved
Benton Facial Recognition Test (BFRT) info iconApproved
EEG info iconApproved
Eye Tracking info iconApproved
Wechsler Intelligence Scale for Children info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
Unravelling the Collective Diagnostic Power Behind the Features in the Autism Diagnostic Observation ScheduleBackground: Autism is a group of heterogeneous disorders defined by deficits in social interaction and communication. Typically, diagnosis depends on the results of a behavioural examination called the Autism Diagnostic Observation Schedule (ADOS). Unfortunately, administration of the ADOS exam is time-consuming and requires a significant amount of expert intervention, leading to delays in diagnosis and access to early intervention programs. The diagnostic power of each feature in the ADOS exam is currently unknown. Our hypothesis is that certain features could be removed from the exam without a significant reduction in diagnostic accuracy, sensitivity or specificity. Objective: Determine the smallest subset of predictive features in ADOS module-1 (an exam variant for patients with minimal verbal skills). Methodology: ADOS module-1 datasets were acquired from the Autism Genetic Resource Exchange and the National Database for Autism Research. The datasets contained 2572 samples with the following labels: autism (1763), autism spectrum (513), and non-autism (296). The datasets were used as input to 4 different cost-sensitive classifiers in Weka (functional trees, LADTree, logistic model trees, and PART). For each classifier, a 10-fold cross validation was preformed and the number of predictive features, accuracy, sensitivity, and specificity was recorded. Results & Conclusion: Each classifier resulted in a reduction of the number of ADOS features required for autism diagnosis. The LADtree classifier was able to obtain the largest reduction, utilizing only 10 of 29 ADOS module-1 features (96.8% accuracy, 96.9% sensitivity, and 95.9% specificity). Overall, these results are a step towards a more efficient behavioural exam for autism diagnosis. 143/2172Secondary AnalysisShared
Combining Gaze and Demographic Feature Descriptors for Autism ClassificationPeople with autism suffer from social challenges and communication difficulties, which may prevent them from leading a fruitful and enjoyable life. It is imperative to diagnose and start treatments for autism as early as possible and, in order to do so, accurate methods of identifying the disorder are vital. We propose a novel method for classifying autism through the use of eye gaze and demographic feature descriptors that include a subject’s age and gender. We construct feature descriptors that incorporate the subject’s age and gender, as well as features based on eye gaze data. Using eye gaze information from the National Database for Autism Research, we tested our constructed feature descriptors on three different classifiers; random regression forests, C4.5 decision tree, and PART. Our proposed method for classifying autism resulted in a top classification rate of 96.2%. 122/836Secondary AnalysisShared
* Data not on individual level