NIMH Data Archive - Data

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¹ Numbers reported are subjects by age

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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

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Neurobehavioral Research on Infants at Risk for SLI and Autism #1900

General
Experiments (0)
Shared Data
Publications (78)
Data Expected (10)
Associated Studies (2)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Neurobehavioral Research on Infants at Risk for SLI and Autism
Collection Investigators:	Helen Tager-flusberg
Collection Description:	The specific aims of the research are (1) to identify markers that distinguish between infants at risk for SLI or ASD and low risk controls; (2) to identify the predictors of later SLI and ASD diagnoses (at 36 months of age) from measures collected between 6 and 12 months of age; and (3) to compare developmental trajectories of key language and related social/cognitive measures between 6 and 36 months in infants with and without clinical outcomes. These aims will be pursued in a longitudinal prospective design following infants from 6 to 36 months of age. Data will be collected on language and social perception using behavioral, eye-tracking and neurophysiological measures as well as general measures of cognitive and brain development (head circumference; EEG).
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	01/27/2012
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$2,419,195.00
Subjects Shared:	32

{"values":[]}

{"values":[["Typical Control",2],["Autism Spectrum Severely Affected",10],["Not Defined",18],["Autism Spectrum Affected",6]]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01DC010290-01	Neurobehavioral Research on Infants at Risk for SLI and Autism	07/01/2009	06/30/2014	250	284	BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)	$2,419,195.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
No records found.

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
Aberrant Behavior Checklist (ABC) - Community	Clinical Assessments	31
Adapted ADOS Module 1	Clinical Assessments	16
Adapted ADOS Module 2	Clinical Assessments	1
Autism Diagnostic Observation Schedule (ADOS) - Module 4	Clinical Assessments	2
Autism Diagnostic Observation Schedule (ADOS)- Module 3	Clinical Assessments	2
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 1	Clinical Assessments	2
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 3	Clinical Assessments	6
BU Demographics	Clinical Assessments	31
BU Medical Form	Clinical Assessments	30
Dean Handedness Inventory	Clinical Assessments	30
Peabody Picture Vocabulary Test, Fourth Edition-Form A	Clinical Assessments	31
Ravens Coloured Progressive Matrices (CPM)	Clinical Assessments	32
Repetitive Behavior Scales - Early Childhood Supplement	Clinical Assessments	31
Research Subject	Clinical Assessments	31
Vineland-II - Parent and Caregiver Rating Form (2005)	Clinical Assessments	29

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
38313269	Create Study	Evaluating early EEG correlates of restricted and repetitive behaviors for toddlers with or without autism.	Research square	Chung, Haerin; Wilkinson, Carol L; Job Said, Alex; Tager-Flusberg, Helen; Nelson, Charles A	January 18, 2024	Not Determined
37546863	Create Study	Developmental trajectories of EEG aperiodic and periodic components: Implications for understanding thalamocortical development during infancy.	bioRxiv : the preprint server for biology	Wilkinson, Carol L; Yankowitz, Lisa; Chao, Jerry Y; Gutiérrez, Rodrigo; Rhoades, Jeff L; Shinnar, Shlomo; Purdon, Patrick L; Nelson, Charles A	March 9, 2024	Not Determined
37262938	Create Study	Associations between EEG trajectories, family income, and cognitive abilities over the first two years of life.	Developmental cognitive neuroscience	Wilkinson, Carol L; Pierce, Lara J; Sideridis, Georgios; Wade, Mark; Nelson, Charles A	June 1, 2023	Not Determined
36933374	Create Study	Associations between attentional biases to fearful faces and social-emotional development in infants with and without an older sibling with autism.	Infant behavior & development	Wagner, Jennifer B; Keehn, Brandon; Tager-Flusberg, Helen; Nelson, Charles A	May 1, 2023	Not Determined
36336205	Create Study	In Context: A Developmental Model of Reward Processing, With Implications for Autism and Sensitive Periods.	Journal of the American Academy of Child and Adolescent Psychiatry	Clements, Caitlin C; Ascunce, Karina; Nelson, Charles A	November 1, 2023	Not Determined
35652157	Create Study	Early predictors of language skills at 3 years of age vary based on diagnostic outcome: A baby siblings research consortium study.	Autism research : official journal of the International Society for Autism Research	Pecukonis, Meredith; Young, Gregory S; Brian, Jessica; Charman, Tony; Chawarska, Katarzyna; Elsabbagh, Mayada; Iverson, Jana M; Jeste, Shafali; Landa, Rebecca; Messinger, Daniel S; Schwichtenberg, A J; Webb, Sara Jane; Zwaigenbaum, Lonnie; Tager-Flusberg, Helen	July 1, 2022	Not Determined
35624989	Create Study	Neuroimaging Techniques as Descriptive and Diagnostic Tools for Infants at Risk for Autism Spectrum Disorder: A Systematic Review.	Brain sciences	Ayoub, Maria J; Keegan, Laura; Tager-Flusberg, Helen; Gill, Simone V	May 5, 2022	Not Determined
35155817	Create Study	How do minimally verbal children and adolescents with autism spectrum disorder use communicative gestures to complement their spoken language abilities?	Autism & developmental language impairments	La Valle, Chelsea; Chenausky, Karen; Tager-Flusberg, Helen	January 1, 2021	Not Determined
35021990	Create Study	Neural correlates of face processing associated with development of social communication in 12-month infants with familial risk of autism spectrum disorder.	Journal of neurodevelopmental disorders	Glauser, Joshua; Wilkinson, Carol L; Gabard-Durnam, Laurel J; Choi, Boin; Tager-Flusberg, Helen; Nelson, Charles A	January 12, 2022	Not Determined
34847887	Create Study	Prediction of autism spectrum disorder diagnosis using nonlinear measures of language-related EEG at 6 and 12 months.	Journal of neurodevelopmental disorders	Peck, Fleming C; Gabard-Durnam, Laurel J; Wilkinson, Carol L; Bosl, William; Tager-Flusberg, Helen; Nelson, Charles A	November 30, 2021	Not Determined
34185234	Create Study	Parental Language Input Predicts Neuroscillatory Patterns Associated with Language Development in Toddlers at Risk of Autism.	Journal of autism and developmental disorders	Romeo, Rachel R; Choi, Boin; Gabard-Durnam, Laurel J; Wilkinson, Carol L; Levin, April R; Rowe, Meredith L; Tager-Flusberg, Helen; Nelson 3rd, Charles A	June 1, 2022	Not Determined
33792804	Create Study	Brief Report: Parents'' Declarative Use of Deictic Gestures Predict Vocabulary Development in Infants at High and Low Risk for Autism Spectrum Disorder.	Journal of autism and developmental disorders	Choi, Boin; Castelbaum, Lauren; McKechnie, Riley; Rowe, Meredith L; Nelson, Charles A; Tager-Flusberg, Helen	February 1, 2022	Not Determined
33632320	Create Study	Increased aperiodic gamma power in young boys with Fragile X Syndrome is associated with better language ability.	Molecular autism	Wilkinson, Carol L; Nelson, Charles A	February 25, 2021	Not Determined
33420647	Create Study	A Longitudinal Study of Parent Gestures, Infant Responsiveness, and Vocabulary Development in Infants at Risk for Autism Spectrum Disorder.	Journal of autism and developmental disorders	Choi, Boin; Shah, Priyanka; Rowe, Meredith L; Nelson, Charles A; Tager-Flusberg, Helen	November 1, 2021	Not Determined
33338817	Create Study	Exploring the relation between brain response to speech at 6-months and language outcomes at 24-months in infants at high and low risk for autism spectrum disorder: A preliminary functional near-infrared spectroscopy study.	Developmental cognitive neuroscience	Pecukonis, Meredith; Perdue, Katherine L; Wong, Jillian; Tager-Flusberg, Helen; Nelson, Charles A	February 1, 2021	Not Determined
32656537	Create Study	Use of longitudinal EEG measures in estimating language development in infants with and without familial risk for autism spectrum disorder.	Neurobiology of language (Cambridge, Mass.)	Wilkinson, Carol L; Gabard-Durnam, Laurel J; Kapur, Kush; Tager-Flusberg, Helen; Levin, April R; Nelson, Charles A	January 2020	Not Determined
32640168	Create Study	Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review.	American journal of speech-language pathology	Butler, Lindsay K; Kiran, Swathi; Tager-Flusberg, Helen	August 4, 2020	Not Determined
32003131	Create Study	Reciprocal Influences Between Parent Input and Child Language Skills in Dyads Involving High- and Low-Risk Infants for Autism Spectrum Disorder.	Autism research : official journal of the International Society for Autism Research	Choi, Boin; Nelson, Charles A; Rowe, Meredith L; Tager-Flusberg, Helen	July 1, 2020	Not Determined
31754946	Create Study	Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder.	Journal of autism and developmental disorders	Kadlaskar, Girija; Seidl, Amanda; Tager-Flusberg, Helen; Nelson, Charles A; Keehn, Brandon	March 2020	Not Determined
31589284	Create Study	Developmental Trajectories of Infants With Multiplex Family Risk for Autism: A Baby Siblings Research Consortium Study.	JAMA neurology	McDonald, Nicole M; Senturk, Damla; Scheffler, Aaron; Brian, Jessica A; Carver, Leslie J; Charman, Tony; Chawarska, Katarzyna; Curtin, Suzanne; Hertz-Piccioto, Irva; Jones, Emily J H; Klin, Ami; Landa, Rebecca; Messinger, Daniel S; Ozonoff, Sally; Stone, Wendy L; Tager-Flusberg, Helen; Webb, Sara Jane; Young, Gregory; Zwaigenbaum, Lonnie; Jeste, Shafali S	January 2020	Not Determined
31519897	Create Study	Longitudinal EEG power in the first postnatal year differentiates autism outcomes.	Nature communications	Gabard-Durnam, Laurel J; Wilkinson, Carol; Kapur, Kush; Tager-Flusberg, Helen; Levin, April R; Nelson, Charles A	September 2019	Not Determined
31355652	Create Study	Attentional bias to fearful faces in infants at high risk for autism spectrum disorder.	Emotion (Washington, D.C.)	Wagner, Jennifer B; Keehn, Brandon; Tager-Flusberg, Helen; Nelson, Charles A	September 2020	Not Determined
31119899	Create Study	Reduced frontal gamma power at 24 months is associated with better expressive language in toddlers at risk for autism.	Autism research : official journal of the International Society for Autism Research	Wilkinson, Carol L; Levin, April R; Gabard-Durnam, Laurel J; Tager-Flusberg, Helen; Nelson, Charles A	August 2019	Not Determined
31016672	Create Study	Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder.	Journal of autism and developmental disorders	Kadlaskar, Girija; Seidl, Amanda; Tager-Flusberg, Helen; Nelson, Charles A; Keehn, Brandon	July 2019	Not Determined
30877417	Create Study	Gesture Development, Caregiver Responsiveness, and Language and Diagnostic Outcomes in Infants at High and Low Risk for Autism.	Journal of autism and developmental disorders	Choi, Boin; Shah, Priyanka; Rowe, Meredith L; Nelson, Charles A; Tager-Flusberg, Helen	July 2020	Not Determined
30628809	Create Study	Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study.	Journal of abnormal psychology	Iverson, Jana M; Shic, Frederick; Wall, Carla A; Chawarska, Katarzyna; Curtin, Suzanne; Estes, Annette; Gardner, Judith M; Hutman, Ted; Landa, Rebecca J; Levin, April R; Libertus, Klaus; Messinger, Daniel S; Nelson, Charles A; Ozonoff, Sally; Sacrey, Lori-Ann R; Sheperd, Kelly; Stone, Wendy L; Tager-Flusberg, Helen B; Wolff, Jason J; Yirmiya, Nurit; Young, Gregory S	January 2019	Not Determined
30131667	Create Study	BEAPP: The Batch Electroencephalography Automated Processing Platform.	Frontiers in neuroscience	Levin, April R; Méndez Leal, Adriana S; Gabard-Durnam, Laurel J; O'Leary, Heather M	January 2018	Not Determined
29717196	Create Study	EEG Analytics for Early Detection of Autism Spectrum Disorder: A data-driven approach.	Scientific reports	Bosl, William J; Tager-Flusberg, Helen; Nelson, Charles A	May 2018	Not Determined
29649977	Create Study	Development of fine motor skills is associated with expressive language outcomes in infants at high and low risk for autism spectrum disorder.	Journal of neurodevelopmental disorders	Choi, Boin; Leech, Kathryn A; Tager-Flusberg, Helen; Nelson, Charles A	April 12, 2018	Not Determined
29456277	Create Study	Differential Attention to Faces in Infant Siblings of Children with Autism Spectrum Disorder and Associations with Later Social and Language Ability.	International journal of behavioral development	Wagner, Jennifer B; Luyster, Rhiannon J; Moustapha, Hana; Tager-Flusberg, Helen; Nelson, Charles A	January 2018	Not Determined
28922545	Create Study	Neural responses to linguistic stimuli in children with and without autism spectrum disorder.	The European journal of neuroscience	Finch, Kayla H; Tager-Flusberg, Helen; Nelson, Charles A	March 2018	Not Determined
28903722	Create Study	EEG power at 3 months in infants at high familial risk for autism.	Journal of neurodevelopmental disorders	Levin AR, Varcin KJ, O'Leary HM, Tager-Flusberg H, Nelson CA	September 2017	Not Determined
28688078	Create Study	Differences in Neural Correlates of Speech Perception in 3 Month Olds at High and Low Risk for Autism Spectrum Disorder.	Journal of autism and developmental disorders	Edwards, Laura A; Wagner, Jennifer B; Tager-Flusberg, Helen; Nelson, Charles A	October 1, 2017	Not Determined
28384664	Create Study	Vocalization Rate and Consonant Production in Toddlers at High and Low Risk for Autism.	Journal of speech, language, and hearing research : JSLHR	Chenausky K, Nelson C, Tager-Flusberg H	April 2017	Not Determined
28339140	Create Study	Acquisition of voice onset time in toddlers at high and low risk for autism spectrum disorder.	Autism research : official journal of the International Society for Autism Research	Chenausky K, Tager-Flusberg H	July 2017	Not Determined
28174606	Create Study	Lateralization of ERPs to speech and handedness in the early development of Autism Spectrum Disorder.	Journal of neurodevelopmental disorders	Finch KH, Seery AM, Talbott MR, Nelson CA, Tager-Flusberg H	January 2017	Not Determined
27829034	Create Study	Auditory-Motor Mapping Training: Comparing the Effects of a Novel Speech Treatment to a Control Treatment for Minimally Verbal Children with Autism.	PloS one	Chenausky K, Norton A, Tager-Flusberg H, Schlaug G	January 2016	Not Determined
27616938	Create Study	Greater Pupil Size in Response to Emotional Faces as an Early Marker of Social-Communicative Difficulties in Infants at High Risk for Autism.	Infancy : the official journal of the International Society on Infant Studies	Wagner, Jennifer B; Luyster, Rhiannon J; Tager-Flusberg, Helen; Nelson, Charles A	September 2016	Not Determined
27417857	Create Study	Non-ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study.	Autism research : official journal of the International Society for Autism Research	Charman, Tony; Young, Gregory S; Brian, Jessica; Carter, Alice; Carver, Leslie J; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Elsabbagh, Mayada; Georgiades, Stelios; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Jones, Emily J; Landa, Rebecca; Macari, Suzanne; Messinger, Daniel S; Nelson, Charles A; Ozonoff, Sally; Saulnier, Celine; Stone, Wendy L; Tager-Flusberg, Helen; Webb, Sara Jane; Yirmiya, Nurit; Zwaigenbaum, Lonnie	January 2017	Not Determined
27358719	Create Study	Commentary: sex difference differences? A reply to Constantino.	Molecular autism	Messinger, Daniel S; Young, Gregory S; Webb, Sara Jane; Ozonoff, Sally; Bryson, Susan E; Carter, Alice; Carver, Leslie; Charman, Tony; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Landa, Rebecca; Nelson, Charles A; Stone, Wendy L; Tager-Flusberg, Helen; Zwaigenbaum, Lonnie	2016	Not Relevant
26953849	Create Study	A developmental neuroscience approach to the search for biomarkers in autism spectrum disorder.	Current opinion in neurology	Varcin, Kandice J; Nelson 3rd, Charles A	April 2016	Not Relevant
26502110	Create Study	Risk Factors Associated With Language in Autism Spectrum Disorder: Clues to Underlying Mechanisms.	Journal of speech, language, and hearing research : JSLHR	Tager-Flusberg H	February 2016	Not Relevant
26478642	Create Study	The role of early visual attention in social development.	International journal of behavioral development	Wagner JB, Luyster RJ, Yim JY, Tager-Flusberg H, Nelson CA	March 1, 2013	Not Determined
26476738	Create Study	Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder.	Journal of autism and developmental disorders	Lazenby DC, Sideridis GD, Huntington N, Prante M, Dale PS, Curtin S, Henkel L, Iverson JM, Carver L, Dobkins K, Akshoomoff N, Tagavi D, Nelson CA, Tager-Flusberg H	March 2016	Not Determined
26408635	Create Study	Comparing methods for assessing receptive language skills in minimally verbal children and adolescents with autism spectrum disorders.	Autism : the international journal of research and practice	Plesa Skwerer D, Jordan SE, Brukilacchio BH, Tager-Flusberg H	July 2016	Not Determined
26335733	Create Study	Defining language impairments in a subgroup of children with autism spectrum disorder.	Science China. Life sciences	Tager-Flusberg, Helen	October 2015	Not Determined
26174704	Create Study	Maternal Vocal Feedback to 9-Month-Old Infant Siblings of Children with ASD.	Autism research : official journal of the International Society for Autism Research	Talbott MR, Nelson CA, Tager-Flusberg H	July 14, 2015	Not Determined
26109246	Create Study	Eye-tracking measurements of language processing: developmental differences in children at high risk for ASD.	Journal of autism and developmental disorders	Chita-Tegmark M, Arunachalam S, Nelson CA, Tager-Flusberg H	October 2015	Not Determined
26088664	Create Study	Shortened Telomeres in Families With a Propensity to Autism.	Journal of the American Academy of Child and Adolescent Psychiatry	Nelson CA, Varcin KJ, Coman NK, DeVivo I, Tager-Flusberg H	July 2015	Not Determined
26045943	Create Study	Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study.	Molecular autism	Messinger, Daniel S; Young, Gregory S; Webb, Sara Jane; Ozonoff, Sally; Bryson, Susan E; Carter, Alice; Carver, Leslie; Charman, Tony; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Landa, Rebecca; Nelson, Charles A; Stone, Wendy L; Tager-Flusberg, Helen; Zwaigenbaum, Lonnie	January 2015	Not Determined
25813603	Create Study	Inhibition-Based Biomarkers for Autism Spectrum Disorder.	Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics	Levin, April R; Nelson, Charles A	July 2015	Not Determined
25808162	Create Study	Atypical hemispheric specialization for faces in infants at risk for autism spectrum disorder.	Autism research : official journal of the International Society for Autism Research	Keehn B, Vogel-Farley V, Tager-Flusberg H, Nelson CA	April 2015	Not Determined
25703030	Create Study	Diary Reports of Concerns in Mothers of Infant Siblings of Children with Autism Across the First Year of Life.	Journal of autism and developmental disorders	Talbott, Meagan R; Nelson, Charles A; Tager-Flusberg, Helen	July 2015	Not Determined
25457930	Create Study	18-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: a baby siblings research consortium study.	Journal of the American Academy of Child and Adolescent Psychiatry	Chawarska, Katarzyna; Shic, Frederick; Macari, Suzanne; Campbell, Daniel J; Brian, Jessica; Landa, Rebecca; Hutman, Ted; Nelson, Charles A; Ozonoff, Sally; Tager-Flusberg, Helen; Young, Gregory S; Zwaigenbaum, Lonnie; Cohen, Ira L; Charman, Tony; Messinger, Daniel S; Klin, Ami; Johnson, Scott; Bryson, Susan	December 2014	Not Determined
25140874	Create Study	Functional connectivity in the first year of life in infants at risk for autism spectrum disorder: an EEG study.	PloS one	Righi, Giulia; Tierney, Adrienne L; Tager-Flusberg, Helen; Nelson, Charles A	2014	Not Determined
24353165	Create Study	Assessing the minimally verbal school-aged child with autism spectrum disorder.	Autism research : official journal of the International Society for Autism Research	Kasari C, Brady N, Lord C, Tager-Flusberg H	December 2013	Not Relevant
24183618	Create Study	Neural measures of social attention across the first years of life: characterizing typical development and markers of autism risk.	Developmental cognitive neuroscience	Luyster RJ, Powell C, Tager-Flusberg H, Nelson CA	April 2014	Not Determined
24128733	Create Study	The use of near-infrared spectroscopy in the study of typical and atypical development.	NeuroImage	Vanderwert RE, Nelson CA	January 15, 2014	Not Determined
24124067	Create Study	Minimally verbal school-aged children with autism spectrum disorder: the neglected end of the spectrum.	Autism research : official journal of the International Society for Autism Research	Tager-Flusberg H, Kasari C	December 2013	Not Determined
23989937	Create Study	Alpha asymmetry in infants at risk for autism spectrum disorders.	Journal of autism and developmental disorders	Gabard-Durnam, Laurel; Tierney, Adrienne L; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A	February 2015	Not Determined
23975145	Create Study	Guidelines and best practices for electrophysiological data collection, analysis and reporting in autism.	Journal of autism and developmental disorders	Webb, Sara Jane; Bernier, Raphael; Henderson, Heather A; Johnson, Mark H; Jones, Emily J H; Lerner, Matthew D; McPartland, James C; Nelson, Charles A; Rojas, Donald C; Townsend, Jeanne; Westerfield, Marissa	February 2015	Not Relevant
23964223	Create Study	Functional connectivity in the first year of life in infants at-risk for autism: a preliminary near-infrared spectroscopy study.	Frontiers in human neuroscience	Keehn, Brandon; Wagner, Jennifer B; Tager-Flusberg, Helen; Nelson, Charles A	2013	Not Determined
23585026	Create Study	Maternal gesture use and language development in infant siblings of children with autism spectrum disorder.	Journal of autism and developmental disorders	Talbott, Meagan R; Nelson, Charles A; Tager-Flusberg, Helen	January 2015	Not Determined
23576966	Create Study	Neural processing of facial identity and emotion in infants at high-risk for autism spectrum disorders.	Frontiers in human neuroscience	Fox, Sharon E; Wagner, Jennifer B; Shrock, Christine L; Tager-Flusberg, Helen; Nelson, Charles A	2013	Not Determined
23452686	Create Study	Beyond autism: a baby siblings research consortium study of high-risk children at three years of age.	Journal of the American Academy of Child and Adolescent Psychiatry	Messinger, Daniel; Young, Gregory S; Ozonoff, Sally; Dobkins, Karen; Carter, Alice; Zwaigenbaum, Lonnie; Landa, Rebecca J; Charman, Tony; Stone, Wendy L; Constantino, John N; Hutman, Ted; Carver, Leslie J; Bryson, Susan; Iverson, Jana M; Strauss, Mark S; Rogers, Sally J; Sigman, Marian	March 2013	Not Determined
23445896	Create Study	Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity.	BMC medicine	Peters JM, Taquet M, Vega C, Jeste SS, Fernández IS, Tan J, Nelson CA, Sahin M, Warfield SK	2013	Not Determined
23362034	Create Study	Identifying early-risk markers and developmental trajectories for language impairment in neurodevelopmental disorders.	Developmental disabilities research reviews	Luyster RJ, Seery A, Talbott MR, Tager-Flusberg H	2011	Not Determined
23287023	Create Study	Atypical lateralization of ERP response to native and non-native speech in infants at risk for autism spectrum disorder.	Developmental cognitive neuroscience	Seery AM, Vogel-Farley V, Tager-Flusberg H, Nelson CA	July 2013	Not Determined
22745707	Create Study	Developmental trajectories of resting EEG power: an endophenotype of autism spectrum disorder.	PloS one	Tierney, Adrienne L; Gabard-Durnam, Laurel; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A	2012	Not Determined
22661408	Create Study	Impaired language pathways in tuberous sclerosis complex patients with autism spectrum disorders.	Cerebral cortex (New York, N.Y. : 1991)	Lewis WW, Sahin M, Scherrer B, Peters JM, Suarez RO, Vogel-Farley VK, Jeste SS, Gregas MC, Prabhu SP, Nelson CA, Warfield SK	July 2013	Not Determined
22365458	Create Study	Facing autism: eye tracking paves the way to underlying mechanisms.	Journal of the American Academy of Child and Adolescent Psychiatry	Nelson CA	March 2012	Not Determined
22142677	Create Study	Loss of white matter microstructural integrity is associated with adverse neurological outcome in tuberous sclerosis complex.	Academic radiology	Peters, Jurriaan M; Sahin, Mustafa; Vogel-Farley, Vanessa K; Jeste, Shafali S; Nelson 3rd, Charles A; Gregas, Matthew C; Prabhu, Sanjay P; Scherrer, Benoit; Warfield, Simon K	January 2012	Not Determined
21970828	Create Study	Common neurological co-morbidities in autism spectrum disorders.	Current opinion in pediatrics	Maski, Kiran P; Jeste, Shafali S; Spence, Sarah J	December 2011	Not Determined
21844053	Create Study	Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study.	Pediatrics	Ozonoff, Sally; Young, Gregory S; Carter, Alice; Messinger, Daniel; Yirmiya, Nurit; Zwaigenbaum, Lonnie; Bryson, Susan; Carver, Leslie J; Constantino, John N; Dobkins, Karen; Hutman, Ted; Iverson, Jana M; Landa, Rebecca; Rogers, Sally J; Sigman, Marian; Stone, Wendy L	September 2011	Not Determined
21811483	Create Study	Neural processing of repetition and non-repetition grammars in 7- and 9-month-old infants.	Frontiers in psychology	Wagner, Jennifer B; Fox, Sharon E; Tager-Flusberg, Helen; Nelson, Charles A	2011	Not Determined
21442325	Create Study	Neural correlates of familiar and unfamiliar face processing in infants at risk for autism spectrum disorders.	Brain topography	Luyster RJ, Wagner JB, Vogel-Farley V, Tager-Flusberg H, Nelson CA	October 2011	Not Determined
21342500	Create Study	EEG complexity as a biomarker for autism spectrum disorder risk.	BMC medicine	Bosl W, Tierney A, Tager-Flusberg H, Nelson C	2011	Not Determined
20800990	Create Study	The origins of social impairments in autism spectrum disorder: studies of infants at risk.	Neural networks : the official journal of the International Neural Network Society	Tager-Flusberg, Helen	January 2010	Not Determined

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Contact NDA Help Desk

Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	40	01/15/2013	31	05/15/2013	31	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Ravens Coloured Progressive Matrices (CPM)	40	01/15/2013	32	05/15/2013	32	Approved
ABC Community	40	01/15/2013	31	05/15/2013	31	Approved
ADOS	40	01/15/2013	28	05/15/2013	28	Approved
Medical History	40	01/15/2013	30	05/15/2013	30	Approved
Demographics	40	01/15/2013	31	05/15/2013	31	Approved
Peabody Picture Vocabulary Test, Fourth Edition	40	01/15/2013	31	05/15/2013	31	Approved
Repetitive Behavior Scale - Revised (RBS-R)	40	01/15/2013	31	05/15/2013	31	Approved
Handedness Form	40	01/15/2013	30	05/15/2013	30	Approved
Vineland (Parent and Caregiver)	40	01/15/2013	29	05/15/2013	29	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
Prognostic early snapshot stratification of autism based on adaptive functioning	A major goal of precision medicine is to predict prognosis based on individualized information at the earliest possible points in development. Using early snapshots of adaptive functioning and unsupervised data- driven discovery methods, we uncover highly stable early autism subtypes that yield information relevant to later prognosis. Data from the National Institute of Mental Health Data Archive (NDA) (n = 1,098) was used to uncover three early subtypes (<72 months) that generalize with 96% accuracy. Outcome data from NDA (n = 2,561; mean age, 13 years) also reproducibly clusters into three subtypes with 99% generalization accuracy. Early snapshot subtypes predict developmental trajectories in non-verbal cognitive, language and motor domains and are predictive of membership in different adaptive functioning outcome subtypes. Robust and prognosis- relevant subtyping of autism based on early snapshots of adaptive functioning may aid future research work via prediction of these subtypes with our reproducible stratification model.	29/3517	Secondary Analysis	Shared
Investigating autism etiology and heterogeneity by decision tree algorithm	Autism spectrum disorder (ASD) is a neurodevelopmental disorder that causes deficits in cognition, communication and social skills. ASD, however, is a highly heterogeneous disorder. This heterogeneity has made identifying the etiology of ASD a particularly difficult challenge, as patients exhibit a wide spectrum of symptoms without any unifying genetic or environmental factors to account for the disorder. For better understanding of ASD, it is paramount to identify potential genetic and environmental risk factors that are comorbid with it. Identifying such factors is of great importance to determine potential causes for the disorder, and understand its heterogeneity. Existing large-scale datasets offer an opportunity for computer scientists to undertake this task by utilizing machine learning to reliably and efficiently obtain insight about potential ASD risk factors, which would in turn assist in guiding research in the field. In this study, decision tree algorithms were utilized to analyze related factors in datasets obtained from the National Database for Autism Research (NDAR) consisting of nearly 3000 individuals. We were able to identify 15 medical conditions that were highly associated with ASD diagnoses in patients; furthermore, we extended our analysis to the family medical history of patients and we report six potentially hereditary medical conditions associated with ASD. Associations reported had a 90% accuracy. Meanwhile, gender comparisons highlighted conditions that were unique to each gender and others that overlapped. Those findings were validated by the academic literature, thus opening the way for new directions for the use of decision tree algorithms to further understand the etiology of autism.	8/3382	Secondary Analysis	Shared

* Data not on individual level

helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

Contact NDA Help Desk

Edit

Choose File:	Select File
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Reason*	Characters Remaining:

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Frequently Asked Questions

Glossary