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1 Numbers reported are subjects by age
New Trial
New Project

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment
To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.
SelectExperiment IdExperiment NameExperiment Type
Created On
24HI-NGS_R1Omics02/16/2011
475MB1-10 (CHOP)Omics06/07/2016
490Illumina Infinium PsychArray BeadChip AssayOmics07/07/2016
501PharmacoBOLD Resting StatefMRI07/27/2016
506PVPREFOmics08/05/2016
509ABC-CT Resting v2EEG08/18/2016
13Comparison of FI expression in Autistic and Neurotypical Homo SapiensOmics12/28/2010
18AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics01/06/2011
22Stitching PCR SequencingOmics02/14/2011
26ASD_MethylationOmics03/01/2011
29Microarray family 03 (father, mother, sibling)Omics03/24/2011
37Standard paired-end sequencing of BCRsOmics04/19/2011
38Illumina Mate-Pair BCR sequencingOmics04/19/2011
39Custom Jumping LibrariesOmics04/19/2011
40Custom CapBPOmics04/19/2011
41ImmunofluorescenceOmics05/11/2011
43Autism brain sample genotyping, IlluminaOmics05/16/2011
47ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 SystemOmics08/01/2011
53AGRE Omni1-quadOmics10/11/2011
59AGP genotypingOmics04/03/2012
60Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controlsOmics06/23/2012
63Microemulsion PCR and Targeted Resequencing for Variant Detection in ASDOmics07/20/2012
76Whole Genome Sequencing in Autism FamiliesOmics01/03/2013
519RestingfMRI11/08/2016
90Genotyped IAN SamplesOmics07/09/2013
91NJLAGS Axiom Genotyping ArrayOmics07/16/2013
93AGP genotyping (CNV)Omics09/06/2013
106Longitudinal Sleep Study. H20 200. Channel set 2EEG11/07/2013
107Longitudinal Sleep Study. H20 200. Channel set 3EEG11/07/2013
108Longitudinal Sleep Study. AURA 200EEG11/07/2013
105Longitudinal Sleep Study. H20 200. Channel set 1EEG11/07/2013
109Longitudinal Sleep Study. AURA 400EEG11/07/2013
116Gene Expression Analysis WG-6Omics01/07/2014
131Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1Eye Tracking02/27/2014
132Jeste Lab UCLA ACEii: Animacy - Project 1Eye Tracking02/27/2014
133Jeste Lab UCLA ACEii: Mom Stranger - Project 2Eye Tracking02/27/2014
134Jeste Lab UCLA ACEii: Face Emotion - Project 3Eye Tracking02/27/2014
145AGRE/FMR1_Illumina.JHUOmics04/14/2014
146AGRE/MECP2_Sanger.JHUOmics04/14/2014
147AGRE/MECP2_Junior.JHUOmics04/14/2014
151Candidate Gene Identification in familial AutismOmics06/09/2014
152NJLAGS Whole Genome SequencingOmics07/01/2014
154Math Autism Study - Vinod MenonfMRI07/15/2014
155RestingfMRI07/25/2014
156SpeechfMRI07/25/2014
159EmotionfMRI07/25/2014
160syllable contrastEEG07/29/2014
167School-age naturalistic stimuliEye Tracking09/19/2014
44AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics06/27/2011
45Exome Sequencing of 20 Sporadic Cases of Autism Spectrum DisorderOmics07/15/2011
Collection - Add Experiment
Add Supporting Documentation
Select File

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

Request Submission Exemption
Characters Remaining:
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The Data Expected list for this Collection shows some raw data as missing. Contact the NDA Help Desk with any questions.

Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

[CMS] Attention
[CMS] Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.
[CMS] Error

[CMS]

Unable to change collection phase where targeted enrollment is less than 90%

Delete Submission Exemption
Are you sure you want to delete this submission exemption?
You have requested to move the sharing dates for the following assessments:
Data Expected Item Original Sharing Date New Sharing Date

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Explanation must be between 20 and 200 characters in length.

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New Email Address
Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Pediatric Imaging, Neurocognition, and Genetics (PING)
Terry Jernigan 
The PING Data Resource is the product of a multi-site project involving developmental researchers across the United States including UC San Diego the University of Hawaii UC Los Angeles Children's Hospital of Los Angeles of the University of Southern California UC Davis Kennedy Krieger Institute of Johns Hopkins University Sackler Institute of Cornell University University of Massachusetts Massachusetts General Hospital at Harvard University and Yale University. The Data Resource includes neurodevelopmental histories, information about developing mental and emotional functions, multimodal brain imaging data, and genotypes for well over 1000 children and adolescents between the ages of 3 and 20.
NIMH Data Archive
03/24/2017
Funding Completed
Close Out
No
$9,107,610.00
1,494
Loading Chart...
NIH - Extramural None

PING_Scanner_Protocols.zip Methods Scanner Protocols Qualified Researchers
PING_ImagingReleaseNotes.xlsx Methods Imaging Files Release Notes Qualified Researchers


RC2DA029475-01 Creating a Pediatric Imaging-Genomics Data Resource 09/30/2009 08/31/2013 210 204 UNIVERSITY OF CALIFORNIA, SAN DIEGO $9,107,610.00

helpcenter.collection.general-tab

NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

  • How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?
    During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
  • How do I know when a NDA Collection has been created?
    When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
  • Is a single grant number ever associated with more than one Collection?
    The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
  • Why is there sometimes more than one grant included in a Collection?
    In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Administrator Privilege
    A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
  • Collection Owner
    Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
  • Collection Phase
    The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
    • Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
    • Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
    • Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed: A grant/project has reached the project end date.
  • Collection Title
    An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
  • Grant
    Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
  • Supporting Documentation
    Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
  • NIH Research Initiative
    NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
  • Permission Group
    Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
  • Planned Enrollment
    Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
  • Actual Enrollment
    Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
  • NDA Collection
    A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
  • Data Use Limitations
    Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
  • Total Subjects Shared
    The total number of unique subjects for whom data have been shared and are available for users with permission to access data.
IDNameCreated DateStatusType
653PING REST04/27/2017ApprovedfMRI
781PING Genetics (gDNA)08/24/2017ApprovedOmics
785PING Genetics (mtDNA)09/14/2017ApprovedOmics
helpcenter.collection.experiments-tab

NDA Help Center

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Can an Experiment be associated with more than one Collection?

    Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

  • Experiment Status
    An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
  • Experiment ID
    The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.
Dimensional Change Card Sort Test (DCCS) Clinical Assessments 1493
Family Developmental History Clinical Assessments 1493
Flanker Task Clinical Assessments 1493
FreeSurfer Volumetrix Imaging 1493
Genomics Subject Genomics 1493
Image Imaging 763
Imitation Based Assessment of Memory Clinical Assessments 1493
NIH Toolbox List Sorting Working Memory Test Clinical Assessments 1493
NIH Toolbox Oral Reading Recognition Test Clinical Assessments 1493
NIH Toolbox Picture Vocabulary Test Clinical Assessments 1493
Pattern Comparison Processing Speed Clinical Assessments 1493
Processed DTI Imaging 1493
Substance Use History Clinical Assessments 1493
helpcenter.collection.shared-data-tab

NDA Help Center

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

  • How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?
    To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
  • Can I get a supplement to share data from a completed research project?
    Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
  • Can I get a supplement to share data from a research project that is still ongoing?
    Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Type
    A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
  • Shared
    The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
38463962Create StudyLifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI.bioRxiv : the preprint server for biologyZhu, Alyssa H; Nir, Talia M; Javid, Shayan; Villalon-Reina, Julio E; Rodrigue, Amanda L; Strike, Lachlan T; de Zubicaray, Greig I; McMahon, Katie L; Wright, Margaret J; Medland, Sarah E; Blangero, John; Glahn, David C; Kochunov, Peter; Håberg, Asta K; Thompson, Paul M; Jahanshad, Neda; Alzheimer’s Disease Neuroimaging InitiativeMarch 1, 2024Not Determined
38395541Create StudyNormative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation.The Lancet. Digital healthGe, Ruiyang; Yu, Yuetong; Qi, Yi Xuan; Fan, Yu-Nan; Chen, Shiyu; Gao, Chuntong; Haas, Shalaila S; New, Faye; Boomsma, Dorret I; Brodaty, Henry; Brouwer, Rachel M; Buckner, Randy; Caseras, Xavier; Crivello, Fabrice; Crone, Eveline A; Erk, Susanne; Fisher, Simon E; Franke, Barbara; Glahn, David C; Dannlowski, Udo; Grotegerd, Dominik; Gruber, Oliver; Hulshoff Pol, Hilleke E; Schumann, Gunter; Tamnes, Christian K; Walter, Henrik; Wierenga, Lara M; Jahanshad, Neda; Thompson, Paul M; Frangou, Sophia; ENIGMA Lifespan Working GroupMarch 1, 2024Not Determined
38076938Create StudyNormative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization.bioRxiv : the preprint server for biologyGe, Ruiyang; Yu, Yuetong; Qi, Yi Xuan; Fan, Yunan Vera; Chen, Shiyu; Gao, Chuntong; Haas, Shalaila S; Modabbernia, Amirhossein; New, Faye; Agartz, Ingrid; Asherson, Philip; Ayesa-Arriola, Rosa; Banaj, Nerisa; Banaschewski, Tobias; Baumeister, Sarah; Bertolino, Alessandro; Boomsma, Dorret I; Borgwardt, Stefan; Bourque, Josiane; Brandeis, Daniel; Breier, Alan; Brodaty, Henry; Brouwer, Rachel M; Buckner, Randy; Buitelaar, Jan K; Cannon, Dara M; Caseras, Xavier; Cervenka, Simon; Conrod, Patricia J; Crespo-Facorro, Benedicto; Crivello, Fabrice; Crone, Eveline A; de Haan, Liewe; de Zubicaray, Greig I; Di Giorgio, Annabella; Erk, Susanne; Fisher, Simon E; Franke, Barbara; Frodl, Thomas; Glahn, David C; Grotegerd, Dominik; Gruber, Oliver; Gruner, Patricia; Gur, Raquel E; Gur, Ruben C; Harrison, Ben J; Hatton, Sean N; Hickie, Ian; Howells, Fleur M; Pol, Hilleke E Hulshoff; Huyser, Chaim; Jernigan, Terry L; Jiang, Jiyang; Joska, John A; Kahn, René S; Kalnin, Andrew J; Kochan, Nicole A; Koops, Sanne; Kuntsi, Jonna; Lagopoulos, Jim; Lazaro, Luisa; Lebedeva, Irina S; Lochner, Christine; Martin, Nicholas G; Mazoyer, Bernard; McDonald, Brenna C; McDonald, Colm; McMahon, Katie L; Nakao, Tomohiro; Nyberg, Lars; Piras, Fabrizio; Portella, Maria J; Qiu, Jiang; Roffman, Joshua L; Sachdev, Perminder S; Sanford, Nicole; Satterthwaite, Theodore D; Saykin, Andrew J; Schumann, Gunter; Sellgren, Carl M; Sim, Kang; Smoller, Jordan W; Soares, Jair; Sommer, Iris E; Spalletta, Gianfranco; Stein, Dan J; Tamnes, Christian K; Thomopolous, Sophia I; Tomyshev, Alexander S; Tordesillas-Gutiérrez, Diana; Trollor, Julian N; van 't Ent, Dennis; van den Heuvel, Odile A; van Erp, Theo Gm; van Haren, Neeltje Em; Vecchio, Daniela; Veltman, Dick J; Walter, Henrik; Wang, Yang; Weber, Bernd; Wei, Dongtao; Wen, Wei; Westlye, Lars T; Wierenga, Lara M; Williams, Steven Cr; Wright, Margaret J; Medland, Sarah; Wu, Mon-Ju; Yu, Kevin; Jahanshad, Neda; Thompson, Paul M; Frangou, SophiaDecember 2, 2023Not Determined
37858734Create StudyPolygenic risk for depression and anterior and posterior hippocampal volume in children and adolescents.Journal of affective disordersHurtado, Hailee; Hansen, Melissa; Strack, Jordan; Vainik, Uku; Decker, Alexandra L; Khundrakpam, Budhachandra; Duncan, Katherine; Finn, Amy S; Mabbott, Donald J; Merz, Emily CJanuary 1, 2024Not Determined
37661008Create StudyBeyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers.Biological psychiatryBoen, Rune; Kaufmann, Tobias; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Ames, David; Andersson, Micael; Armstrong, Nicola J; Artiges, Eric; Atkins, Joshua R; Bauer, Jochen; Benedetti, Francesco; Boomsma, Dorret I; Brodaty, Henry; Brosch, Katharina; Buckner, Randy L; Cairns, Murray J; Calhoun, Vince; Caspers, Svenja; Cichon, Sven; Corvin, Aiden P; Crespo-Facorro, Benedicto; Dannlowski, Udo; David, Friederike S; de Geus, Eco J C; de Zubicaray, Greig I; Desrivières, Sylvane; Doherty, Joanne L; Donohoe, Gary; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fisher, Simon E; Forstner, Andreas J; Fortaner-Uyà, Lidia; Frouin, Vincent; Fukunaga, Masaki; Ge, Tian; Glahn, David C; Goltermann, Janik; Grabe, Hans J; Green, Melissa J; Groenewold, Nynke A; Grotegerd, Dominik; Grøntvedt, Gøril Rolfseng; Hahn, Tim; Hashimoto, Ryota; Hehir-Kwa, Jayne Y; Henskens, Frans A; Holmes, Avram J; Håberg, Asta K; Haavik, Jan; Jacquemont, Sebastien; Jansen, Andreas; Jockwitz, Christiane; Jönsson, Erik G; Kikuchi, Masataka; Kircher, Tilo; Kumar, Kuldeep; Le Hellard, Stephanie; Leu, Costin; Linden, David E; Liu, Jingyu; Loughnan, Robert; Mather, Karen A; McMahon, Katie L; McRae, Allan F; Medland, Sarah E; Meinert, Susanne; Moreau, Clara A; Morris, Derek W; Mowry, Bryan J; Mühleisen, Thomas W; Nenadić, Igor; Nöthen, Markus M; Nyberg, Lars; Ophoff, Roel A; Owen, Michael J; Pantelis, Christos; Paolini, Marco; Paus, Tomas; Pausova, Zdenka; Persson, Karin; Quidé, Yann; Marques, Tiago Reis; Sachdev, Perminder S; Sando, Sigrid B; Schall, Ulrich; Scott, Rodney J; Selbæk, Geir; Shumskaya, Elena; Silva, Ana I; Sisodiya, Sanjay M; Stein, Frederike; Stein, Dan J; Straube, Benjamin; Streit, Fabian; Strike, Lachlan T; Teumer, Alexander; Teutenberg, Lea; Thalamuthu, Anbupalam; Tooney, Paul A; Tordesillas-Gutierrez, Diana; Trollor, Julian N; van 't Ent, Dennis; van den Bree, Marianne B M; van Haren, Neeltje E M; Vázquez-Bourgon, Javier; Völzke, Henry; Wen, Wei; Wittfeld, Katharina; Ching, Christopher R K; Westlye, Lars T; Thompson, Paul M; Bearden, Carrie E; Selmer, Kaja K; Alnæs, Dag; Andreassen, Ole A; Sønderby, Ida E; ENIGMA-CNV Working GroupJanuary 15, 2024Not Determined
36446759Create StudyHypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities.Translational psychiatryPrice, Kaitlyn M; Wigg, Karen G; Eising, Else; Feng, Yu; Blokland, Kirsten; Wilkinson, Margaret; Kerr, Elizabeth N; Guger, Sharon L; Quantitative Trait Working Group of the GenLang Consortium; Fisher, Simon E; Lovett, Maureen W; Strug, Lisa J; Barr, Cathy LNovember 29, 2022Not Determined
35998220Create StudyGenome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.Proceedings of the National Academy of Sciences of the United States of AmericaEising, Else; Mirza-Schreiber, Nazanin; de Zeeuw, Eveline L; Wang, Carol A; Truong, Dongnhu T; Allegrini, Andrea G; Shapland, Chin Yang; Zhu, Gu; Wigg, Karen G; Gerritse, Margot L; Molz, Barbara; Alagöz, Gökberk; Gialluisi, Alessandro; Abbondanza, Filippo; Rimfeld, Kaili; van Donkelaar, Marjolein; Liao, Zhijie; Jansen, Philip R; Andlauer, Till F M; Bates, Timothy C; Bernard, Manon; Blokland, Kirsten; Bonte, Milene; Børglum, Anders D; Bourgeron, Thomas; Brandeis, Daniel; Ceroni, Fabiola; Csépe, Valéria; Dale, Philip S; de Jong, Peter F; DeFries, John C; Démonet, Jean-François; Demontis, Ditte; Feng, Yu; Gordon, Scott D; Guger, Sharon L; Hayiou-Thomas, Marianna E; Hernández-Cabrera, Juan A; Hottenga, Jouke-Jan; Hulme, Charles; Kere, Juha; Kerr, Elizabeth N; Koomar, Tanner; Landerl, Karin; Leonard, Gabriel T; Lovett, Maureen W; Lyytinen, Heikki; Martin, Nicholas G; Martinelli, Angela; Maurer, Urs; Michaelson, Jacob J; Moll, Kristina; Monaco, Anthony P; Morgan, Angela T; Nöthen, Markus M; Pausova, Zdenka; Pennell, Craig E; Pennington, Bruce F; Price, Kaitlyn M; Rajagopal, Veera M; Ramus, Franck; Richer, Louis; Simpson, Nuala H; Smith, Shelley D; Snowling, Margaret J; Stein, John; Strug, Lisa J; Talcott, Joel B; Tiemeier, Henning; van der Schroeff, Marc P; Verhoef, Ellen; Watkins, Kate E; Wilkinson, Margaret; Wright, Margaret J; Barr, Cathy L; Boomsma, Dorret I; Carreiras, Manuel; Franken, Marie-Christine J; Gruen, Jeffrey R; Luciano, Michelle; Müller-Myhsok, Bertram; Newbury, Dianne F; Olson, Richard K; Paracchini, Silvia; Paus, Tomáš; Plomin, Robert; Reilly, Sheena; Schulte-Körne, Gerd; Tomblin, J Bruce; van Bergen, Elsje; Whitehouse, Andrew J O; Willcutt, Erik G; St Pourcain, Beate; Francks, Clyde; Fisher, Simon EAugust 30, 2022Not Determined
35894163Create StudyEducational attainment polygenic scores, socioeconomic factors, and cortical structure in children and adolescents.Human brain mappingMerz, Emily C; Strack, Jordan; Hurtado, Hailee; Vainik, Uku; Thomas, Michael; Evans, Alan; Khundrakpam, BudhachandraNovember 1, 2022Not Determined
35816931Create StudyParental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents.Developmental cognitive neuroscienceNorbom, Linn B; Hanson, Jamie; van der Meer, Dennis; Ferschmann, Lia; Røysamb, Espen; von Soest, Tilmann; Andreassen, Ole A; Agartz, Ingrid; Westlye, Lars T; Tamnes, Christian KAugust 1, 2022Not Determined
35809969Create StudyDiffusion tensor estimation with transformer neural networks.Artificial intelligence in medicineKarimi, Davood; Gholipour, AliAugust 1, 2022Not Determined
35220023Create StudyDo aggregate, multimodal structural neuroimaging measures replicate regional developmental differences observed in highly cited cellular histological studies?Developmental cognitive neuroscienceHagler Jr, Donald J; Thompson, Wesley K; Chen, Chi-Hua; Reuter, Chase; Akshoomoff, Natacha; Brown, Timothy T; Pediatric Imaging, Neurocognition, and Genetics StudyApril 1, 2022Not Determined
35027165Create StudyMapping Complex Brain Torque Components and Their Genetic Architecture and Phenomic Associations in 24,112 Individuals.Biological psychiatryZhao, Lu; Matloff, William; Shi, Yonggang; Cabeen, Ryan P; Toga, Arthur WApril 15, 2022Not Determined
34140357Create StudyCommon genetic variation influencing human white matter microstructure.Science (New York, N.Y.)Zhao, Bingxin; Li, Tengfei; Yang, Yue; Wang, Xifeng; Luo, Tianyou; Shan, Yue; Zhu, Ziliang; Xiong, Di; Hauberg, Mads E; Bendl, Jaroslav; Fullard, John F; Roussos, Panagiotis; Li, Yun; Stein, Jason L; Zhu, HongtuJune 18, 2021Not Determined
34001886Create StudyTranscriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits.Nature communicationsZhao, Bingxin; Shan, Yue; Yang, Yue; Yu, Zhaolong; Li, Tengfei; Wang, Xifeng; Luo, Tianyou; Zhu, Ziliang; Sullivan, Patrick; Zhao, Hongyu; Li, Yun; Zhu, HongtuMay 17, 2021Not Determined
33595143Create StudyCortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years.Human brain mappingFrangou, Sophia; Modabbernia, Amirhossein; Williams, Steven C R; Papachristou, Efstathios; Doucet, Gaelle E; Agartz, Ingrid; Aghajani, Moji; Akudjedu, Theophilus N; Albajes-Eizagirre, Anton; Alnaes, Dag; Alpert, Kathryn I; Andersson, Micael; Andreasen, Nancy C; Andreassen, Ole A; Asherson, Philip; Banaschewski, Tobias; Bargallo, Nuria; Baumeister, Sarah; Baur-Streubel, Ramona; Bertolino, Alessandro; Bonvino, Aurora; Boomsma, Dorret I; Borgwardt, Stefan; Bourque, Josiane; Brandeis, Daniel; Breier, Alan; Brodaty, Henry; Brouwer, Rachel M; Buitelaar, Jan K; Busatto, Geraldo F; Buckner, Randy L; Calhoun, Vincent; Canales-Rodríguez, Erick J; Cannon, Dara M; Caseras, Xavier; Castellanos, Francisco X; Cervenka, Simon; Chaim-Avancini, Tiffany M; Ching, Christopher R K; Chubar, Victoria; Clark, Vincent P; Conrod, Patricia; Conzelmann, Annette; Crespo-Facorro, Benedicto; Crivello, Fabrice; Crone, Eveline A; Dale, Anders M; Dannlowski, Udo; Davey, Christopher; de Geus, Eco J C; de Haan, Lieuwe; de Zubicaray, Greig I; den Braber, Anouk; Dickie, Erin W; Di Giorgio, Annabella; Doan, Nhat Trung; Dørum, Erlend S; Ehrlich, Stefan; Erk, Susanne; Espeseth, Thomas; Fatouros-Bergman, Helena; Fisher, Simon E; Fouche, Jean-Paul; Franke, Barbara; Frodl, Thomas; Fuentes-Claramonte, Paola; Glahn, David C; Gotlib, Ian H; Grabe, Hans-Jörgen; Grimm, Oliver; Groenewold, Nynke A; Grotegerd, Dominik; Gruber, Oliver; Gruner, Patricia; Gur, Rachel E; Gur, Ruben C; Hahn, Tim; Harrison, Ben J; Hartman, Catharine A; Hatton, Sean N; Heinz, Andreas; Heslenfeld, Dirk J; Hibar, Derrek P; Hickie, Ian B; Ho, Beng-Choon; Hoekstra, Pieter J; Hohmann, Sarah; Holmes, Avram J; Hoogman, Martine; Hosten, Norbert; Howells, Fleur M; Hulshoff Pol, Hilleke E; Huyser, Chaim; Jahanshad, Neda; James, Anthony; Jernigan, Terry L; Jiang, Jiyang; Jönsson, Erik G; Joska, John A; Kahn, Rene; Kalnin, Andrew; Kanai, Ryota; Klein, Marieke; Klyushnik, Tatyana P; Koenders, Laura; Koops, Sanne; Krämer, Bernd; Kuntsi, Jonna; Lagopoulos, Jim; Lázaro, Luisa; Lebedeva, Irina; Lee, Won Hee; Lesch, Klaus-Peter; Lochner, Christine; Machielsen, Marise W J; Maingault, Sophie; Martin, Nicholas G; Martínez-Zalacaín, Ignacio; Mataix-Cols, David; Mazoyer, Bernard; McDonald, Colm; McDonald, Brenna C; McIntosh, Andrew M; McMahon, Katie L; McPhilemy, Genevieve; Meinert, Susanne; Menchón, José M; Medland, Sarah E; Meyer-Lindenberg, Andreas; Naaijen, Jilly; Najt, Pablo; Nakao, Tomohiro; Nordvik, Jan E; Nyberg, Lars; Oosterlaan, Jaap; de la Foz, Víctor Ortiz-García; Paloyelis, Yannis; Pauli, Paul; Pergola, Giulio; Pomarol-Clotet, Edith; Portella, Maria J; Potkin, Steven G; Radua, Joaquim; Reif, Andreas; Rinker, Daniel A; Roffman, Joshua L; Rosa, Pedro G P; Sacchet, Matthew D; Sachdev, Perminder S; Salvador, Raymond; Sánchez-Juan, Pascual; Sarró, Salvador; Satterthwaite, Theodore D; Saykin, Andrew J; Serpa, Mauricio H; Schmaal, Lianne; Schnell, Knut; Schumann, Gunter; Sim, Kang; Smoller, Jordan W; Sommer, Iris; Soriano-Mas, Carles; Stein, Dan J; Strike, Lachlan T; Swagerman, Suzanne C; Tamnes, Christian K; Temmingh, Henk S; Thomopoulos, Sophia I; Tomyshev, Alexander S; Tordesillas-Gutiérrez, Diana; Trollor, Julian N; Turner, Jessica A; Uhlmann, Anne; van den Heuvel, Odile A; van den Meer, Dennis; van der Wee, Nic J A; van Haren, Neeltje E M; van 't Ent, Dennis; van Erp, Theo G M; Veer, Ilya M; Veltman, Dick J; Voineskos, Aristotle; Völzke, Henry; Walter, Henrik; Walton, Esther; Wang, Lei; Wang, Yang; Wassink, Thomas H; Weber, Bernd; Wen, Wei; West, John D; Westlye, Lars T; Whalley, Heather; Wierenga, Lara M; Wittfeld, Kat (see original citation for additional authors)January 1, 2022Not Determined
33570244Create StudySubcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years.Human brain mappingDima, Danai; Modabbernia, Amirhossein; Papachristou, Efstathios; Doucet, Gaelle E; Agartz, Ingrid; Aghajani, Moji; Akudjedu, Theophilus N; Albajes-Eizagirre, Anton; Alnaes, Dag; Alpert, Kathryn I; Andersson, Micael; Andreasen, Nancy C; Andreassen, Ole A; Asherson, Philip; Banaschewski, Tobias; Bargallo, Nuria; Baumeister, Sarah; Baur-Streubel, Ramona; Bertolino, Alessandro; Bonvino, Aurora; Boomsma, Dorret I; Borgwardt, Stefan; Bourque, Josiane; Brandeis, Daniel; Breier, Alan; Brodaty, Henry; Brouwer, Rachel M; Buitelaar, Jan K; Busatto, Geraldo F; Buckner, Randy L; Calhoun, Vincent; Canales-Rodríguez, Erick J; Cannon, Dara M; Caseras, Xavier; Castellanos, Francisco X; Cervenka, Simon; Chaim-Avancini, Tiffany M; Ching, Christopher R K; Chubar, Victoria; Clark, Vincent P; Conrod, Patricia; Conzelmann, Annette; Crespo-Facorro, Benedicto; Crivello, Fabrice; Crone, Eveline A; Dannlowski, Udo; Dale, Anders M; Davey, Christopher; de Geus, Eco J C; de Haan, Lieuwe; de Zubicaray, Greig I; den Braber, Anouk; Dickie, Erin W; Di Giorgio, Annabella; Doan, Nhat Trung; Dørum, Erlend S; Ehrlich, Stefan; Erk, Susanne; Espeseth, Thomas; Fatouros-Bergman, Helena; Fisher, Simon E; Fouche, Jean-Paul; Franke, Barbara; Frodl, Thomas; Fuentes-Claramonte, Paola; Glahn, David C; Gotlib, Ian H; Grabe, Hans-Jörgen; Grimm, Oliver; Groenewold, Nynke A; Grotegerd, Dominik; Gruber, Oliver; Gruner, Patricia; Gur, Rachel E; Gur, Ruben C; Hahn, Tim; Harrison, Ben J; Hartman, Catharine A; Hatton, Sean N; Heinz, Andreas; Heslenfeld, Dirk J; Hibar, Derrek P; Hickie, Ian B; Ho, Beng-Choon; Hoekstra, Pieter J; Hohmann, Sarah; Holmes, Avram J; Hoogman, Martine; Hosten, Norbert; Howells, Fleur M; Hulshoff Pol, Hilleke E; Huyser, Chaim; Jahanshad, Neda; James, Anthony; Jernigan, Terry L; Jiang, Jiyang; Jönsson, Erik G; Joska, John A; Kahn, Rene; Kalnin, Andrew; Kanai, Ryota; Klein, Marieke; Klyushnik, Tatyana P; Koenders, Laura; Koops, Sanne; Krämer, Bernd; Kuntsi, Jonna; Lagopoulos, Jim; Lázaro, Luisa; Lebedeva, Irina; Lee, Won Hee; Lesch, Klaus-Peter; Lochner, Christine; Machielsen, Marise W J; Maingault, Sophie; Martin, Nicholas G; Martínez-Zalacaín, Ignacio; Mataix-Cols, David; Mazoyer, Bernard; McDonald, Colm; McDonald, Brenna C; McIntosh, Andrew M; McMahon, Katie L; McPhilemy, Genevieve; Meinert, Susanne; Menchón, José M; Medland, Sarah E; Meyer-Lindenberg, Andreas; Naaijen, Jilly; Najt, Pablo; Nakao, Tomohiro; Nordvik, Jan E; Nyberg, Lars; Oosterlaan, Jaap; de la Foz, Víctor Ortiz-García; Paloyelis, Yannis; Pauli, Paul; Pergola, Giulio; Pomarol-Clotet, Edith; Portella, Maria J; Potkin, Steven G; Radua, Joaquim; Reif, Andreas; Rinker, Daniel A; Roffman, Joshua L; Rosa, Pedro G P; Sacchet, Matthew D; Sachdev, Perminder S; Salvador, Raymond; Sánchez-Juan, Pascual; Sarró, Salvador; Satterthwaite, Theodore D; Saykin, Andrew J; Serpa, Mauricio H; Schmaal, Lianne; Schnell, Knut; Schumann, Gunter; Sim, Kang; Smoller, Jordan W; Sommer, Iris; Soriano-Mas, Carles; Stein, Dan J; Strike, Lachlan T; Swagerman, Suzanne C; Tamnes, Christian K; Temmingh, Henk S; Thomopoulos, Sophia I; Tomyshev, Alexander S; Tordesillas-Gutiérrez, Diana; Trollor, Julian N; Turner, Jessica A; Uhlmann, Anne; van den Heuvel, Odile A; van den Meer, Dennis; van der Wee, Nic J A; van Haren, Neeltje E M; Van't Ent, Dennis; van Erp, Theo G M; Veer, Ilya M; Veltman, Dick J; Voineskos, Aristotle; Völzke, Henry; Walter, Henrik; Walton, Esther; Wang, Lei; Wang, Yang; Wassink, Thomas H; Weber, Bernd; Wen, Wei; West, John D; Westlye, Lars T; Whalley, Heather; Wierenga, Lara M; Williams, Steven C R; Wittfeld, Katharin (see original citation for additional authors)January 1, 2022Not Determined
33231097Create StudyNeurocognitive Dysfunction and Smaller Brain Volumes in Adolescents and Adults With a Fontan Circulation.CirculationVerrall, Charlotte E; Yang, Joseph Y M; Chen, Jian; Schembri, Adrian; d'Udekem, Yves; Zannino, Diana; Kasparian, Nadine A; du Plessis, Karin; Grieve, Stuart M; Welton, Thomas; Barton, Belinda; Gentles, Thomas L; Celermajer, David S; Attard, Chantal; Rice, Kathryn; Ayer, Julian; Mandelstam, Simone; Winlaw, David S; Mackay, Mark T; Cordina, RachaelMarch 2, 2021Not Determined
32744409Create StudyMaturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study.Human brain mappingNorbom, Linn B; Rokicki, Jaroslav; Alnaes, Dag; Kaufmann, Tobias; Doan, Nhat Trung; Andreassen, Ole A; Westlye, Lars T; Tamnes, Christian KNovember 1, 2020Not Determined
32501641Create StudyAssociations Between Body Weight, Hippocampal Volume, and Tissue Signal Intensity in 12- to 18-Year-Olds.Obesity (Silver Spring, Md.)Mestre, Zoe; Bischoff-Grethe, Amanda; Wierenga, Christina E; Jernigan, Terry; Eichen, Dawn M; Chang, Linda; Ernst, Thomas; Boutelle, Kerri NJuly 2020Not Determined
32251906Create StudyBrain morphometric differences in youth with and without perinatally-acquired HIV: A cross-sectional study.NeuroImage. ClinicalLewis-de Los Angeles, C Paula; Williams, Paige L; Jenkins, Lisanne M; Huo, Yanling; Malee, Kathleen; Alpert, Kathryn I; Uban, Kristina A; Herting, Megan M; Csernansky, John G; Nichols, Sharon L; Van Dyke, Russell B; Sowell, Elizabeth R; Wang, Lei; Pediatric HIV/AIDS Cohort Study (PHACS) and the Pediatric Imaging, Neurocognition, and Genetics (PING) StudyJanuary 1, 2020Not Determined
32193296Create StudyThe genetic architecture of the human cerebral cortex.Science (New York, N.Y.)Grasby, Katrina L; Jahanshad, Neda; Painter, Jodie N; Colodro-Conde, Lucía; Bralten, Janita; Hibar, Derrek P; Lind, Penelope A; Pizzagalli, Fabrizio; Ching, Christopher R K; McMahon, Mary Agnes B; Shatokhina, Natalia; Zsembik, Leo C P; Thomopoulos, Sophia I; Zhu, Alyssa H; Strike, Lachlan T; Agartz, Ingrid; Alhusaini, Saud; Almeida, Marcio A A; Alnæs, Dag; Amlien, Inge K; Andersson, Micael; Ard, Tyler; Armstrong, Nicola J; Ashley-Koch, Allison; Atkins, Joshua R; Bernard, Manon; Brouwer, Rachel M; Buimer, Elizabeth E L; Bülow, Robin; Bürger, Christian; Cannon, Dara M; Chakravarty, Mallar; Chen, Qiang; Cheung, Joshua W; Couvy-Duchesne, Baptiste; Dale, Anders M; Dalvie, Shareefa; de Araujo, Tânia K; de Zubicaray, Greig I; de Zwarte, Sonja M C; den Braber, Anouk; Doan, Nhat Trung; Dohm, Katharina; Ehrlich, Stefan; Engelbrecht, Hannah-Ruth; Erk, Susanne; Fan, Chun Chieh; Fedko, Iryna O; Foley, Sonya F; Ford, Judith M; Fukunaga, Masaki; Garrett, Melanie E; Ge, Tian; Giddaluru, Sudheer; Goldman, Aaron L; Green, Melissa J; Groenewold, Nynke A; Grotegerd, Dominik; Gurholt, Tiril P; Gutman, Boris A; Hansell, Narelle K; Harris, Mathew A; Harrison, Marc B; Haswell, Courtney C; Hauser, Michael; Herms, Stefan; Heslenfeld, Dirk J; Ho, New Fei; Hoehn, David; Hoffmann, Per; Holleran, Laurena; Hoogman, Martine; Hottenga, Jouke-Jan; Ikeda, Masashi; Janowitz, Deborah; Jansen, Iris E; Jia, Tianye; Jockwitz, Christiane; Kanai, Ryota; Karama, Sherif; Kasperaviciute, Dalia; Kaufmann, Tobias; Kelly, Sinead; Kikuchi, Masataka; Klein, Marieke; Knapp, Michael; Knodt, Annchen R; Krämer, Bernd; Lam, Max; Lancaster, Thomas M; Lee, Phil H; Lett, Tristram A; Lewis, Lindsay B; Lopes-Cendes, Iscia; Luciano, Michelle; Macciardi, Fabio; Marquand, Andre F; Mathias, Samuel R; Melzer, Tracy R; Milaneschi, Yuri; Mirza-Schreiber, Nazanin; Moreira, Jose C V; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Najt, Pablo; Nakahara, Soichiro; Nho, Kwangsik; Olde Loohuis, Loes M; Orfanos, Dimitri Papadopoulos; Pearson, John F; Pitcher, Toni L; Pütz, Benno; Quidé, Yann; Ragothaman, Anjanibhargavi; Rashid, Faisal M; Reay, William R; Redlich, Ronny; Reinbold, Céline S; Repple, Jonathan; Richard, Geneviève; Riedel, Brandalyn C; Risacher, Shannon L; Rocha, Cristiane S; Mota, Nina Roth; Salminen, Lauren; Saremi, Arvin; Saykin, Andrew J; Schlag, Fenja; Schmaal, Lianne; Schofield, Peter R; Secolin, Rodrigo; Shapland, Chin Yang; Shen, Li; Shin, Jean; Shumskaya, Elena; Sønderby, Ida E; Sprooten, Emma; Tansey, Katherine E; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Turner, Jessica A; Uhlmann, Anne; Vallerga, Costanza Ludovica; van der Meer, Dennis; van Donkelaar, Marjolein M J; van Eijk, Liza; van Erp, Theo G M; van Haren, Neeltje E M; van Rooij, Daan; van Tol, Marie-José; Veldink, Jan H; Verhoef, Ellen; Walton, Esther; Wang, Mingyuan; Wang, Yunpeng; Wardlaw, Joanna M; Wen, Wei; Westlye, Lars T; Whelan, Christopher D; Witt, Stephanie H; Wittfeld, Katharina; Wolf, Christiane; Wolfers, Thomas; Wu, Jing Qin; Yasuda, Clarissa L; Zaremba, Dario; Zhang, Zuo; Zwiers, Marcel P; Artiges, Eric; Assareh, Amelia A; Ayesa-Arriola, Rosa; Belger, Aysenil; Brandt, Christine L; Brown, Gregory G; Cichon, Sven; Curran, Joanne E; Davies, Gareth E; Degenhardt, Franziska; Dennis, Michelle F; Dietsche, Bruno; Djurovic, Srdjan; Doherty, Colin P; Espiritu, Ryan; Garijo, Daniel; Gil, Yolanda; Gowland, Penny A; Green, Robert C; Häusler, Alexander N; Heindel, Walter; Ho, Beng-Choon; Hoffmann, Wolfgang U; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Jack Jr, Clifford R; Jang, MiHyun; Jansen (see original citation for additional authors)March 20, 2020Not Determined
31990937Create StudyGenome wide association study of incomplete hippocampal inversion in adolescents.PloS oneCury, Claire; Scelsi, Marzia Antonella; Toro, Roberto; Frouin, Vincent; Artiges, Eric; Grigis, Antoine; Heinz, Andreas; Lemaître, Hervé; Martinot, Jean-Luc; Poline, Jean-Baptiste; Smolka, Michael N; Walter, Henrik; Schumann, Gunter; Altmann, Andre; Colliot, Olivier; IMAGEN ConsortiumJanuary 2020Not Determined
31744324Create StudyBrain Development Includes Linear and Multiple Nonlinear Trajectories: A Cross-Sectional Resting-State Functional Magnetic Resonance Imaging Study.Brain connectivityFaghiri, Ashkan; Stephen, Julia M; Wang, Yu-Ping; Wilson, Tony W; Calhoun, Vince DDecember 2019Not Determined
31676860Create StudyGenome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.Nature geneticsZhao, Bingxin; Luo, Tianyou; Li, Tengfei; Li, Yun; Zhang, Jingwen; Shan, Yue; Wang, Xifeng; Yang, Liuqing; Zhou, Fan; Zhu, Ziliang; Alzheimer’s Disease Neuroimaging Initiative; Pediatric Imaging, Neurocognition and Genetics; Zhu, HongtuNovember 1, 2019Not Determined
31228595Create StudyDevelopmental trajectories of the human embryologic brain regions.Neuroscience lettersOishi K, Chotiyanonta J, Wu D, Miller MI, Mori S, Oishi K, August 2019Not Determined
31054076Create StudyImputation Strategy for Reliable Regional MRI Morphological Measurements.NeuroinformaticsSta Cruz, Shaina; Dinov, Ivo D; Herting, Megan M; González-Zacarías, Clio; Kim, Hosung; Toga, Arthur W; Sepehrband, FarshidJanuary 2020Not Determined
30995994Create StudyMultivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth.Journal of medical geneticsTruong, Dongnhu Thuy; Adams, Andrew Kenneth; Paniagua, Steven; Frijters, Jan C; Boada, Richard; Hill, Dina E; Lovett, Maureen W; Mahone, E Mark; Willcutt, Erik G; Wolf, Maryanne; Defries, John C; Gialluisi, Alessandro; Francks, Clyde; Fisher, Simon E; Olson, Richard K; Pennington, Bruce F; Smith, Shelley D; Bosson-Heenan, Joan; Gruen, Jeffrey R; Pediatric, Imaging, Neurocognition, and Genetics ConsortiumAugust 2019Not Determined
30992540Create StudyRole of BDNF in the development of an OFC-amygdala circuit regulating sociability in mouse and human.Molecular psychiatryLi, Anfei; Jing, Deqiang; Dellarco, Danielle V; Hall, Baila S; Yang, Ruirong; Heilberg, Ross T; Huang, Chienchun; Liston, Conor; Casey, B J; Lee, Francis SMarch 2021Not Determined
30941828Create StudyCommon genetic variants have associations with human cortical brain regions and risk of schizophrenia.Genetic epidemiologyBi X, Feng L, Wang S, Lin Z, Li T, Zhao B, Zhu H, Zhang HJuly 2019Not Determined
30898336Create StudyAge-Normative Pathways of Striatal Connectivity Related to Clinical Symptoms in the General Population.Biological psychiatryBarber AD, Sarpal DK, John M, Fales CL, Mostofsky SH, Malhotra AK, Karlsgodt KH, Lencz T, June 2019Not Determined
30534064Create StudyConnectivity of the Human Number Form Area Reveals Development of a Cortical Network for Mathematics.Frontiers in human neuroscienceNemmi, Federico; Schel, Margot A; Klingberg, TorkelJanuary 2018Not Determined
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25257096Create StudyComparison of optical and MR-based tracking.Magnetic resonance in medicineGumus K, Keating B, White N, Andrews-Shigaki B, Armstrong B, Maclaren J, Zaitsev M, Dale A, Ernst TSeptember 2015Not Determined
25183788Create StudyDiffusion-weighted imaging in cancer: physical foundations and applications of restriction spectrum imaging.Cancer researchWhite NS, Mcdonald C, Mcdonald CR, Farid N, Kuperman J, Karow D, Schenker-Ahmed NM, Bartsch H, Rakow-Penner R, Holland D, Shabaik A, Bjørnerud A, Hope T, Hattangadi-Gluth J, Liss M, Parsons JK, Chen CC, Raman S, Margolis D, Reiter RE, Marks L, Kesari S, Mundt AJ, Kane CJ, Kaine CJ, et al.September 2014Not Determined
25135423Create StudyCombining diffusion and perfusion differentiates tumor from bevacizumab-related imaging abnormality (bria).Journal of neuro-oncologyFarid N, Almeida-Freitas DB, White NS, Mcdonald CR, Kuperman JM, Almutairi AA, Muller KA, Vandenberg SR, Kesari S, Dale AMDecember 2014Not Determined
25111045Create StudyStructural growth trajectories and rates of change in the first 3 months of infant brain development.JAMA neurologyHolland D, Chang L, Ernst TM, Curran M, Buchthal SD, Alicata D, Skranes J, Johansen H, Hernandez A, Yamakawa R, Kuperman JM, Dale AMOctober 2014Not Determined
24865593Create StudySchizophrenia-risk variant rs6994992 in the neuregulin-1 gene on brain developmental trajectories in typically developing children.Translational psychiatryDouet V, Chang L, Pritchett A, Lee K, Keating B, Bartsch H, Jernigan TL, Dale A, Akshoomoff N, Murray S, Bloss C, Kennedy DN, Amaral D, Gruen J, Kaufmann WE, Casey BJ, Sowell E, Ernst TMay 2014Not Determined
24786909Create StudyShared common variants in prostate cancer and blood lipids.International journal of epidemiologyAndreassen OA, Zuber V, Thompson WK, Schork AJ, Bettella F, Djurovic S, Desikan RS, Mills IG, Dale AMAugust 2014Not Determined
24650325Create StudyPhenX RISING: real world implementation and sharing of PhenX measures.BMC medical genomicsMcCarty, Catherine A; Huggins, Wayne; Aiello, Allison E; Bilder, Robert M; Hariri, Ahmad; Jernigan, Terry L; Newman, Erik; Sanghera, Dharambir K; Strauman, Timothy J; Zeng, Yi; Ramos, Erin M; Junkins, Heather A; PhenX RISING networkMarch 2014Not Determined
24632141Create StudyBrain volume reductions in adolescent heavy drinkers.Developmental cognitive neuroscienceSqueglia LM, Rinker DA, Bartsch H, Castro N, Chung Y, Dale AM, Jernigan TL, Tapert SFJuly 2014Not Determined
24357182Create StudyDistinct effects of nuclear volume fraction and cell diameter on high b-value diffusion MRI contrast in tumors.Magnetic resonance in medicineWhite NS, Dale AMNovember 2014Not Determined
24319118Create StudyBoosting the power of schizophrenia genetics by leveraging new statistical tools.Schizophrenia bulletinAndreassen OA, Thompson WK, Dale AMJanuary 2014Not Determined
24219608Create StudyThe NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING).NeuropsychologyAkshoomoff, Natacha; Newman, Erik; Thompson, Wesley K; McCabe, Connor; Bloss, Cinnamon S; Chang, Linda; Amaral, David G; Casey, B J; Ernst, Thomas M; Frazier, Jean A; Gruen, Jeffrey R; Kaufmann, Walter E; Kenet, Tal; Kennedy, David N; Libiger, Ondrej; Mostofsky, Stewart; Murray, Sarah S; Sowell, Elizabeth R; Schork, Nicholas; Dale, Anders M; Jernigan, Terry LJanuary 2014Not Determined
24082094Create StudyGenetic topography of brain morphology.Proceedings of the National Academy of Sciences of the United States of AmericaChen CH, Fiecas M, Gutiérrez ED, Panizzon MS, Eyler LT, Vuoksimaa E, Thompson WK, Fennema-Notestine C, Hagler DJ, Jernigan TL, Neale MC, Franz CE, Lyons MJ, Fischl B, Tsuang MT, Dale AM, Kremen WSOctober 2013Not Determined
24077983Create StudyGenetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood.Brain imaging and behaviorDouet, Vanessa; Chang, Linda; Cloak, Christine; Ernst, ThomasJune 2014Not Determined
24024963Create StudyGenome-wide association study of shared components of reading disability and language impairment.Genes, brain, and behaviorEicher, J D; Powers, N R; Miller, L L; Akshoomoff, N; Amaral, D G; Bloss, C S; Libiger, O; Schork, N J; Darst, B F; Casey, B J; Chang, L; Ernst, T; Frazier, J; Kaufmann, W E; Keating, B; Kenet, T; Kennedy, D; Mostofsky, S; Murray, S S; Sowell, E R; Bartsch, H; Kuperman, J M; Brown, T T; Hagler Jr, D J; Dale, A M; Jernigan, T L; St Pourcain, B; Davey Smith, G; Ring, S M; Gruen, J R; Pediatric Imaging, Neurocognition, and Genetics StudyNovember 2013Not Determined
23637625Create StudyImproved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.PLoS geneticsAndreassen, Ole A; Thompson, Wesley K; Schork, Andrew J; Ripke, Stephan; Mattingsdal, Morten; Kelsoe, John R; Kendler, Kenneth S; O'Donovan, Michael C; Rujescu, Dan; Werge, Thomas; Sklar, Pamela; Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups; Roddey, J Cooper; Chen, Chi-Hua; McEvoy, Linda; Desikan, Rahul S; Djurovic, Srdjan; Dale, Anders MApril 2013Not Determined
23637621Create StudyAll SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.PLoS geneticsSchork, Andrew J; Thompson, Wesley K; Pham, Phillip; Torkamani, Ali; Roddey, J Cooper; Sullivan, Patrick F; Kelsoe, John R; O'Donovan, Michael C; Furberg, Helena; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium; Schork, Nicholas J; Andreassen, Ole A; Dale, Anders MApril 2013Not Determined
23578667Create StudyLongitudinal restriction spectrum imaging is resistant to pseudoresponse in patients with high-grade gliomas treated with bevacizumab.AJNR. American journal of neuroradiologyKothari, Pranay; White, Nathan S; Farid, Nikdokht; Chung, Romy; Kuperman, Joshua M; Girard, Holly M; Shankaranarayanan, Ajit; Kesari, Santosh; McDonald, Carrie R; Dale, Anders MSeptember 2013Not Determined
23499725Create StudyCognitive reserve moderates the association between hippocampal volume and episodic memory in middle age.NeuropsychologiaVuoksimaa, Eero; Panizzon, Matthew S; Chen, Chi-Hua; Eyler, Lisa T; Fennema-Notestine, Christine; Fiecas, Mark Joseph A; Fischl, Bruce; Franz, Carol E; Grant, Michael D; Jak, Amy J; Lyons, Michael J; Neale, Michael C; Thompson, Wesley K; Tsuang, Ming T; Xian, Hong; Dale, Anders M; Kremen, William SMay 2013Not Determined
23375658Create StudyImproved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.American journal of human geneticsAndreassen, Ole A; Djurovic, Srdjan; Thompson, Wesley K; Schork, Andrew J; Kendler, Kenneth S; O'Donovan, Michael C; Rujescu, Dan; Werge, Thomas; van de Bunt, Martijn; Morris, Andrew P; McCarthy, Mark I; International Consortium for Blood Pressure GWAS; Diabetes Genetics Replication and Meta-analysis Consortium; Psychiatric Genomics Consortium Schizophrenia Working Group; Roddey, J Cooper; McEvoy, Linda K; Desikan, Rahul S; Dale, Anders MFebruary 2013Not Determined
23275591Create StudyRecovery of white matter tracts in regions of peritumoral FLAIR hyperintensity with use of restriction spectrum imaging.AJNR. American journal of neuroradiologyMcDonald, C R; White, N S; Farid, N; Lai, G; Kuperman, J M; Bartsch, H; Hagler, D J; Kesari, S; Carter, B S; Chen, C C; Dale, A MJune 2013Not Determined
23169628Create StudyLong-term influence of normal variation in neonatal characteristics on human brain development.Proceedings of the National Academy of Sciences of the United States of AmericaWalhovd KB, Fjell AM, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Roddey JC, Erhart M, Mccabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst TM, Frazier J, Gruen JR, Kaufmann WE, Murray SS, Van Zijl P, Mostofsky S, Dale AM, et al.December 2012Not Determined
23169482Create StudyProbing tissue microstructure with restriction spectrum imaging: Histological and theoretical validation.Human brain mappingWhite, Nathan S; Leergaard, Trygve B; D'Arceuil, Helen; Bjaalie, Jan G; Dale, Anders MFebruary 2013Not Determined
23150548Create StudyMultimodal imaging of the self-regulating developing brain.Proceedings of the National Academy of Sciences of the United States of AmericaFjell AM, Walhovd KB, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Venkatraman V, Roddey JC, Erhart M, Mccabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Darst BF, Schork NJ, Casey BJ, Chang L, Ernst TM, Gruen JR, Kaufmann WE, Kenet T, Frazier J, Murray SS, Sowell ER, et al.November 2012Not Determined
23139079Create StudyImproved conspicuity and delineation of high-grade primary and metastatic brain tumors using "restriction spectrum imaging": quantitative comparison with high B-value DWI and ADC.AJNR. American journal of neuroradiologyWhite NS, Mcdonald CR, Farid N, Kuperman JM, Kesari S, Dale AMMay 2013Not Determined
23007644Create StudyBrain development during the preschool years.Neuropsychology reviewBrown TT, Jernigan TLDecember 2012Not Determined
22917206Create StudyBlood-based gene expression signatures of infants and toddlers with autism.Journal of the American Academy of Child and Adolescent PsychiatryGlatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne ESeptember 2012Not Determined
22902750Create StudyNeuroanatomical assessment of biological maturity.Current biology : CBBrown TT, Kuperman JM, Chung Y, Erhart M, Mccabe C, Hagler DJ, Venkatraman VK, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kaufmann WE, Kenet T, Kennedy DN, Murray SS, Sowell ER, Jernigan TL, Dale AMSeptember 2012Not Determined
22822038Create StudyDiencephalic-mesencephalic junction dysplasia: a novel recessive brain malformation.Brain : a journal of neurologyZaki MS, Saleem SN, Dobyns WB, Barkovich AJ, Bartsch H, Dale AM, Ashtari M, Akizu N, Gleeson JG, Grijalvo-Perez AMAugust 2012Not Determined
22461613Create StudyHierarchical genetic organization of human cortical surface area.Science (New York, N.Y.)Chen CH, Gutierrez ED, Thompson W, Panizzon MS, Jernigan TL, Eyler LT, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AMMarch 2012Not Determined
22457638Create StudyAge-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages.PLoS geneticsChow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne EJanuary 2012Not Determined
22343285Create StudyAssociation of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.Proceedings of the National Academy of Sciences of the United States of AmericaBakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM,, et al.March 2012Not Determined
22174699Create StudyAn assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design.PLoS geneticsVrieze, Scott I; McGue, Matt; Miller, Michael B; Legrand, Lisa N; Schork, Nicholas J; Iacono, William GDecember 2011Not Determined
22099457Create StudyGenetic influences on cortical regionalization in the human brain.NeuronChen CH, Panizzon MS, Eyler LT, Jernigan TL, Thompson W, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Hamza S, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AMNovember 2011Not Determined
21912896Create StudyLower glial metabolite levels in brains of young children with prenatal nicotine exposure.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyChang, Linda; Cloak, Christine C; Jiang, Caroline S; Hoo, Aaron; Hernandez, Antonette B; Ernst, Thomas MMarch 2012Not Determined
21849792Create StudyA geographic cline of skull and brain morphology among individuals of European Ancestry.Human heredityBakken TE, Dale AM, Schork NJJanuary 2011Not Determined
21839162Create StudyAnnotating individual human genomes.GenomicsTorkamani A, Scott-Van Zeeland AA, Topol EJ, Schork NJOctober 2011Not Determined
21810643Create StudyAssociation of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia.Archives of general psychiatryBakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork NJAugust 2011Not Determined
21779892Create StudyProspective motion correction improves diagnostic utility of pediatric MRI scans.Pediatric radiologyKuperman JM, Brown TT, Ahmadi ME, Erhart MJ, White NS, Roddey JC, Shankaranarayanan A, Han ET, Rettmann D, Dale AMDecember 2011Not Determined
21489384Create StudyPostnatal brain development: structural imaging of dynamic neurodevelopmental processes.Progress in brain researchJernigan TL, Baaré WF, Stiles J, Madsen KSJanuary 2011Not Determined
21135382Create StudyHIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study.NeurologyHeaton RK, Clifford DB, Franklin DR, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, Mcarthur JC, Morgello S, Simpson DM, Mccutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, et al.December 2010Not Determined
21042938Create StudyThe basics of brain development.Neuropsychology reviewStiles, Joan; Jernigan, Terry LDecember 2010Not Determined
20542120Create StudyProspective motion correction of high-resolution magnetic resonance imaging data in children.NeuroImageBrown TT, Kuperman JM, Erhart M, White NS, Roddey JC, Shankaranarayanan A, Han ET, Rettmann D, Dale AMOctober 2010Not Determined
19683725Create StudySegmental brain volumes and cognitive and perceptual correlates in 15-year-old adolescents with low birth weight.The Journal of pediatricsMartinussen M, Flanders DW, Fischl B, Busa E, Løhaugen GC, Skranes J, Vangberg TR, Brubakk AM, Haraldseth O, Dale AMDecember 2009Not Determined
helpcenter.collection.publications-tab

NDA Help Center

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

  • How can I determine if a publication is relevant?
    Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
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    PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

  • Create Study
    A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
  • Not Determined Publication
    Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
  • Not Relevant Publication
    A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
  • PubMed
    PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
  • PubMed ID
    The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
  • Relevant Publication
    A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
Identifying genetic risk variants associated with brain volumetric phenotypes via K-sample Ball Divergence methodRegional human brain volumes including total area, average thickness, and total volume are heritable and associated with neurological disorders. However, the genetic architecture of brain structure and function is still largely unknown and worthy of exploring. The Pediatric Imaging, Neurocognition, and Genetics (PING) dataset provides an excellent resource with genome-wide genetic data and the related neuroimaging data. In this study, we perform genome-wide association studies (GWAS) of 315 brain volumetric phenotypes from the PING dataset including 1,036 samples with 539,865 single-nucleotide polymorphisms (SNPs). We introduce a nonparametric test based on K-sample Ball Divergence (KBD) to identify genetic risk variants that influence regional brain volumes. We carry out simulations to demonstrate that KBD is a powerful test for identifying significant SNPs associated with multivariate phenotypes while controlling the type I error rate. We successfully identify 9 SNPs below a significance level of 〖5*10〗^(-6) for the PING data. Among the nine identified genetic variants, two SNPs rs486179 and rs562110 are located in the ADRA1A gene that is a well-known risk factor of mental illness, such as schizophrenia and attention deficit hyperactivity disorder (ADHD). Our study suggests that the nonparametric test KBD is an effective method for identifying genetic variants associated with complex diseases in large-scale GWAS of multiple phenotypes.1494/1494Secondary AnalysisShared
PING Genomics Derived DataThe PING Data Resource is the product of a multi-site project involving developmental researchers across the United States including UC San Diego the University of Hawaii UC Los Angeles Childrens Hospital of Los Angeles of the University of Southern California UC Davis Kennedy Krieger Institute of Johns Hopkins University Sackler Institute of Cornell University University of Massachusetts Massachusetts General Hospital at Harvard University and Yale University. The Data Resource includes neurodevelopmental histories, information about developing mental and emotional functions, multimodal brain imaging data, and genotypes for well over 1000 children and adolescents between the ages of 3 and 20.1493/1493Primary AnalysisShared
Diffusion-weighted derivatives of PINGDiffusion-weighted magnetic resonance imaging (dMRI) allows for the in-vivo assessment of anatomical white matter in the brain, thus allowing the depiction of structural connectivity. Using structural processing techniques and related methods, a growing body of literature has illustrated that connectomics is a crucial aspect to assessing the brain in health and disease. The Pediatric Imaging Neurocognition and Genetics (PING) dataset was collected and released openly to contribute to the assessment of typical brain development in a pediatric sample. This current work details the processing of diffusion-weighted images from the PING dataset, including rigorous quality assessment and fine-tuning of parameters at every step, to increase the accessibility of these data for connectomic analysis. This processing provides state-of-the-art diffusion measures, both classical diffusion tensor imaging (DTI) and more advanced HARDI-based metrics, enabling the evaluation not only of structural white matter but also of integrated multimodal analyses, i.e. combining structural information from dMRI with functional or gray matter analyses.809/809Secondary AnalysisShared
Decoding individual variation of brain age estimates in typical developmentDecoding individual variation of brain age estimates in typical development768/768Secondary AnalysisShared
Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disordersCortical development during childhood and adolescence has been characterised in recent years using metrics derived from Magnetic Resonance Imaging (MRI). Changes in cortical thickness are greatest in the first two decades of life and recapitulate the hierarchical, genetic organisation of the cortex, highlighting the potential early impact of gene expression on differences in cortical architecture over the lifespan. It is important to further our understanding of the possible neurobiological mechanisms the underlie cortical morphology as alterations in cortical thickness can act as a potential phenotypic marker of several common neurodevelopmental and psychiatric disorders. In this study, we combine MRI acquired from a typically-developing childhood population with gene expression databases to test the hypothesis that disrupted mechanisms common to neurodevelopmental disorders are encoded by genes expressed early in development and nested within those associated with typical cortical remodelling in childhood. We find that differential rates of thinning across the developing cortex are associated with spatially-varying gradients of gene expression. Genes that are expressed highly in regions of accelerated thinning are expressed predominantly in neurons, involved in synaptic remodeling, and associated with common cognitive and neurodevelopmental disorders. Further, we identify subsets of genes that are highly expressed in the prenatal period and jointly associated with both developmental cortical morphology and neurodevelopmental disorders. 754/754Secondary AnalysisShared
PING study derived dataChildren from lower income backgrounds tend to have poorer memory and language abilities than their wealthier peers. It has been proposed that these cognitive gaps reflect effects of income-related stress on hippocampal structure, but the empirical evidence for this relationship has not been clear. Here, we examine how family income gaps in cognition relate to the anterior hippocampus, given its high sensitivity to stress, versus the posterior hippocampus. We find that anterior (but not posterior) hippocampal volumes positively correlate with family income up to an annual income of ~$75,000. Income-related differences in the anterior (but not posterior) hippocampus also predicted the strength of the gaps in memory and language. These findings add anatomical specificity to current theories by suggesting a stronger relationship between family income and anterior than posterior hippocampal volumes and offer a potential mechanism through which lower income differ cognitively. 703/703Primary AnalysisShared
Charting shared developmental trajectories of cortical thickness and structural connectivity in childhood and adolescenceThe cortex is organised into broadly hierarchical functional systems with distinct neuroanatomical characteristics reflected by macroscopic measures of cortical morphology. Diffusion-weighted MRI allows the delineation of areal connectivity, changes to which reflect the ongoing maturation of white matter tracts. These developmental processes are intrinsically linked with timing coincident with the development of cognitive function. In this study, we use a data-driven multivariate approach, non-negative matrix factorisation, to define cortical regions that co-vary together across a large paediatric cohort (n=456) and are associated with specific subnetworks of cortical connectivity. We find that age between 3 and 21 years is associated with accelerated cortical thinning in fronto-parietal regions, whereas relative thinning of primary motor and sensory regions is slower. Together, the subject-specific weights of the derived set of components can be combined to predict chronological age. Structural connectivity networks reveal a relative increase in strength in connection within, as opposed to between hemispheres that vary in line with cortical changes. We confirm our findings in an independent sample. 456/456Secondary AnalysisShared
A human craniofacial life-course: cross-sectional morphological covariations during postnatal growth, adolescence, and agingCovariations between anatomical structures are fundamental to craniofacial ontogeny, maturation and aging and yet are rarely studied in such a cognate fashion. Here we offer a comprehensive investigation of the human craniofacial complex using freely available software and MRI datasets representing 575 individuals from 0 to 79 years old. We employ both standard craniometrics methods as well as Procrustes based analyses to capture and document cross-sectional trends. Findings suggest that anatomical structures behave primarily as modules, and manifest integrated patterns of shape change as they compete for space, particularly with relative expansions of the brain during early postnatal life and of the face during puberty. Sexual dimorphism was detected in infancy and intensified during adolescence with gender differences in the magnitude and pattern of morphological covariation as well as of aging. These findings partly support the spatial-packing hypothesis and reveal important insights into phenotypic adjustments to deep-rooted, and presumably genetically defined, trajectories of morphological size and shape change that characterise the normal human craniofacial life-course.188/308Secondary AnalysisShared
* Data not on individual level
helpcenter.collection.associated-studies-tab

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

  • How do I associate a study to my collection?
    Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

  • Associated Studies Tab
    A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.
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