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NDAR provides a single access to de-identified autism research data. For permission to download data, you will need an NDAR account with approved access to NDAR or a connected repository (AGRE, IAN, or the ATP). For NDAR access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

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The filters you have selected from various query interfaces will be stored here, in the 'Filter Cart'. The database will be queried using filters added to your 'Filter Cart', when multiple filters are defined, each will be executed using 'AND' logic, so with each filter that is applied the result set gets smaller.

From the 'Filter Cart' you can inspect each of the filters that have been defined, and you also have the option to remove filters. The 'Filter Cart' itself will display the number of filters applied along with the number of subjects that are identified by the combination of those filters. For example a GUID filter with two subjects, followed by a GUID filter for just one of those subjects would return only data for the subject that is in both GUID filters.

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1 Numbers reported are subjects by age
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

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Please enter the name of the data structure to search or if your definition does not exist, please upload that definition so that it can be appropriately defined for submission. Multiple data structures may be associated with a single Data Expected entry. Please add only one data structure per assessment.

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Shared

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

General

Title, investigators, and Collection Description may be edited along with the Collection Phase. For Collection Phase, the options Pre-enrollment, Enrollment, and Completed can be chosen allowing the Collection Owner to indicate the stage of data collection.

Funding Source

The ability to associate the funding source for the project is provided. For NIH funded grants, linkage to Project Reporter information (e.g. R01MH123456) is supported. Projects funded by others, including the URL of the project, are listed. Non NIH funded projects will become available here to link that data with the appropriate funding agency.

Supporting Documentation

Any documents related to the project may be uploaded clarifying the data or acquisition methods used may be uploaded and made available here. The default is to share these documents to the general public. An option to share only to qualified Researchers is also an option.

Clinical Trials

For clinical trials, the option to link to the clinical trial in clinicaltrials.gov is optionally provided.

Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
The Met Signaling System, Autism and Gastrointestinal Dysfunction.
Pat R. Levitt 
This dataset contains three types of individuals: with ASD and with gastrointestinal dysfunction; with ASD but without gastrointestinal dysfunction; and without ASD but with gastrointestinal dysfunction.
NDAR
Closed
Shared
$570,222.00
299
150
131
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NIH - Extramural None


R21HD065289-01 The MET Signaling System,Autism and Gastrointestinal Dysfunction 09/30/2009 08/31/2011 150 131 UNIVERSITY OF SOUTHERN CALIFORNIA $570,222.00

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Experiments

To create a new Omics, eye tracking, fMRI, or EEG experiment, press the "+ New Experiment" button. Once an experiment is created, then raw files for these types of experiments should be provided, associating the experiment – through Experiment_ID – with the metadata defined in the experiments interface.

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Observation Schedule (ADOS) - Module 4 Clinical Assessments 3
Autism Diagnostic Observation Schedule (ADOS)- Module 1 Clinical Assessments 37
Autism Diagnostic Observation Schedule (ADOS)- Module 2 Clinical Assessments 16
Autism Diagnostic Observation Schedule (ADOS)- Module 3 Clinical Assessments 72
Diet Diary Clinical Assessments 112
Questionnaire on Pediatric GI Symptoms: Rome III Parent Clinical Assessments 169
Social Responsiveness Scale (SRS) Clinical Assessments 166

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDAR data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
27837921Create StudyThe Pleiotropic MET Receptor Network: Circuit Development and the Neural-Medical Interface of Autism.Biological psychiatryEagleson KL, Xie Z, Levitt PSeptember 2016Not Determined
26404703Create StudyBrief Report: Recruitment and Retention of Minority Children for Autism Research.Journal of autism and developmental disordersZamora I, Williams ME, Higareda M, Wheeler BY, Levitt PFebruary 2016Not Determined
26011086Create StudyPatterns of Risk for Multiple Co-Occurring Medical Conditions Replicate Across Distinct Cohorts of Children with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism ResearchAldinger KA, Lane CJ, Veenstra-Vanderweele J, Levitt PDecember 2015Not Determined
24686340Create StudyThe psychologist as an interlocutor in autism spectrum disorder assessment: insights from a study of spontaneous prosody.Journal of speech, language, and hearing research : JSLHRBone D, Lee CC, Black MP, Williams ME, Lee S, Levitt P, Narayanan SAugust 2014Not Determined
23844202Create StudyEnrichment of elevated plasma F2t-isoprostane levels in individuals with autism who are stratified by presence of gastrointestinal dysfunction.PloS oneGorrindo P, Lane CJ, Lee EB, McLaughlin B, Levitt P2013Not Determined
22511450Create StudyGastrointestinal dysfunction in autism: parental report, clinical evaluation, and associated factors.Autism research : official journal of the International Society for Autism ResearchGorrindo P, Williams KC, Lee EB, Walker LS, McGrew SG, Levitt PApril 2012Not Determined
help.tab.dataexpected

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.
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Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Diet/Food Diary/Log info iconApproved
ADOS info iconApproved
Research Subject and Pedigree info iconApproved
Social Responsiveness Scale (SRS) info iconApproved
genomics/omics info iconApproved
Gastrointestinal (GI) History info iconApproved
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study Name Description Number of Subjects
Collection / Total
Data Use State
Gastrointestinal Dysfunction in Autism: Parental Report, Clinical Evaluation, and Associated Factors The objectives of this study were to characterize gastrointestinal dysfunction (GID) in autism spectrum disorder (ASD), to examine parental reports of GID relative to evaluations by pediatric gastroenterologists, and to explore factors associated with GID in ASD. One hundred twenty-one children were recruited into three groups: co-occurring ASD and GID, ASD without GID, and GID without ASD. A pediatric gastroenterologist evaluated both GID groups. Parents in all three groups completed questionnaires about their child`s behavior and GI symptoms, and a dietary journal. Functional constipation was the most common type of GID in children with ASD (85.0%). Parental report of any GID was highly concordant with a clinical diagnosis of any GID (92.1%). Presence of GID in children with ASD was not associated with distinct dietary habits or medication status. Odds of constipation were associated with younger age, increased social impairment, and lack of expressive language (adjusted odds ratio in nonverbal children: 11.98, 95% confidence interval 2.54-56.57). This study validates parental concerns for GID in children with ASD, as parents were sensitive to the existence, although not necessarily the nature, of GID. The strong association between constipation and language impairment highlights the need for vigilance by health-care providers to detect and treat GID in children with ASD. Medications and diet, commonly thought to contribute to GID in ASD, were not associated with GID status. These findings are consistent with a hypothesis that GID in ASD represents pleiotropic expression of genetic risk factors. 91 / 91 Primary Analysis Shared
* Data not on individual level
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